St John’s Wort and Propecia – Hair Loss Information by Dr. William Rassman

I see in a previous post that you believe that St. John’s Wort will not directly contribute to hair loss. My question is, will St. John’s Wort inhibit or decrease the effectiveness of Propecia? Since Propecia is absorbed in the liver, and St. John’s Wort has been shown to decrease absorbtion of certain drugs, could it also be affecting the level of DHT bockers in the blood stream, thereby reducing propecia’s potency? I currently only take 2 300 mg tablets of St. John’s Wort at bedtime (I take my Propecia at bed time as well). Thanks in advance for your reply.

St. John’s wort is an herbal product used for its flavor or potential therapeutic in treating mild to moderate depression. In my opinion, a healthy liver should not have a problem with both St. John’s wort and Propecia. Discuss this with your prescribing physician. Like many other herbal products, there is not enough research on long term treatment, safety, and effectiveness of this product.

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