More Effective — Avodart or Proscar? – Hair Loss Information by Dr. William Rassman

Do you think Avodart 0.5mg or Propecia 5mg is more effective for hair loss?

First, Avodart (dutasteride) is not FDA approved for the treatment of male pattern baldness (MPB), although because of its mechanism it should work in the same manner. Perhaps one day it will be approved, but it currently is not. Tests are presently underway in an approved FDA contractor to determine the safety and effectiveness of dutasteride. Early studies show it is more effective at much higher dosages which may cause sterility in young men.

There is no Propecia 5mg — you’re confusing it with Proscar, which is 5mg finasteride (for prostate treatment). Propecia is 1mg of finasteride and is FDA approved for the treatment of MPB. Propecia and Proscar are the same drug in different dosages.

Mixed Causes of Hair Loss for Mother and Son – Hair Loss Information by Dr. William Rassman

Tonight I read a very interesting page on the site of the American Hair Loss Association with a list of prescription drugs that can “cause temporary hair loss, trigger the onset of male and female pattern baldness, and even cause permanent hair loss”. I began this research for my 52 year old mother, who after recently having a heart attack, began taking Lipitor, Coreg, Plavix and Altace. I love her and it breaks my heart that she is having to endure a cosmetic issue in addition to everything else. Imagine my surprise when I found that six drugs I have taken for significant periods over the last 10 years were also listed: Paxil, Zoloft, Tazorac (Vitamin A derivative), Retin-A, Synthroid and Tapazole for hyperthyroidism.

How my heart sank.

For about two years, I have been trying to cope with my rapidly thinning hair and temporal recession at age 23. And I really haven’t. If anything, my attitude has gotten worse as it has progressed. I take my Propecia religiously, and I avoid myself in the mirror. It makes me sick – but now there is something that makes me even sicker.

Previously, my abundant good sense would have told me that if my baldness were medicinally linked, pattern baldness, which is genetic, would not present itself, and all hair loss would be reversed upon cessation of the medication. I believe, given the lovely cocktail of drugs I have been absorbing since age 12, I have “triggered the onset of pattern baldness”. The slim chance of (I’m guessing) 10% that one of these drugs would induce what probably would have happened 30 years later increased to 60%. I am sort of fuming – piping hot..really, really angry about this.

Luckily, I am entering a stage in my life where I’m realizing my genetic predisposition to certain diseases. Cancer, Heart Disease, Grave’s Disease, Diabetes and Depression are all thrown in to make my life more interesting. I am trying to realize this and lead a healthy life, taking as many preventative measures as I can. While it does make me angry, the thought of one of my conditions not being caused by faulty genes, and instead by medications to treat what those faulty genes caused, rather makes me sort of hopeful. I am off the acne, depression and thyroid medications, so is there some treatment I could begin specific to my case, and possibly, many other cases? Surely my only option isn’t Propecia. Is there something else I can do to reverse the damage Vitamin A, SSRI’s, and thryroid medications caused? And what can my poor mother do?

I apologize in advance for dropping such a tangled complexity in your lap. Please help us.

Thank you

You are certainly pouring your heart out and taking too much blame for what is going on. We take medications when we are in need of them; some can cause hair loss. Both you and your mother need to see a good doctor. I wish I could offer more than just a physician recommendation, but without an examination I just don’t see this being quite that simple.

As you are on the east coast of the US, I can recommend Dr. Robert Bernstein in New York, who can develop a Master Plan for both you and your mother. The information you supplied is packed with interesting stuff and many readers may find your experience helpful. Thank you for sending this. Good luck.


Every Time I Cut My Hair Short with Clippers, Areas of Hair Don’t Grow Back! – Balding Blog

For years I have been using hairs clippers with a #1 or #2 guard to cut my hair. Each time after using the clippers I recieve several areas of hair that either don’t grow back or only fine little hairs show. There is never any scalp or blood present after using the clippers…sometimes I will feel a pinch. I have seen several doctors with no success…they simply don’t know. I’m forced at this point to keep it short…if not the hairs grows out very stringy and thin. Also, my most recent haircut resulted in my hair line at my temples being removed…my hairline is now over my ears instead of starting in front of my ears.

Finally, I swim twice a week…use chlorine shampoo and eat a very health diet. I have a full head hair with a limited amount of thinning at the crown…I’m 38 years of age. HELP

From what you are telling me, it almost sounds like you are starting to recede your hairline at the temples, which may be a sign of male pattern baldness (MPB). The miniaturized hairs that are impacted by the genetics grows slowly, if it grows at all — or perhaps the chlorine may even be harmful to your hair. Before I could provide a real answer your question, you’d need to have a miniaturization study to rule out MPB or other medical causes of hair loss. Please consult a doctor who is experienced in this field.




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Cyclosporine A and Regrowing Hair? – Hair Loss Information by Dr. William Rassman

Good day,
First, I’d like to say that I appreciate this site for it’s complete and very honest answers. I regularly come to this sight for information. So, thank you!

Second, I just read an interesting paper concerning hair stem cells, the protein NFATc1, its inhibition by cyclosporine A, etc. This paper is authored by Elaine Fuchs from Rockefeller University. This paper is to be published in the journal, “Cell.”

Here is the link: NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells

My question: Since it is already an approved drug, would topical application of cyclosporine A help in slowing or possibly even regrowing hair?

Since this drug is not approved by the FDA for use in treating hair loss, I would strongly discourage you from using it for that purpose. We know that cyclosporine, as it is used now, has many side effects which would make it not worth taking, as it could negatively impact you. This is a dangerous drug used for treating difficult medical conditions. On the positive side, this study will only help further our understanding of hair stem cells and potential new treatments for hair loss.


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Bald Spot from Dirty Clippers, Part 2 – Hair Loss Information by Dr. William Rassman

I was wondering if you could get anything that would cause hair loss from dirty clippers. I read one blog but still feel that the answer was not there. I am very sorry to bother you but it is very important to me. I know there is a thousand things that cause hair loss but I have never heard that Dirty or Clean Clippers could cause any of it. Except lice of course! Thanks for responding.

Sincerely, Interested reader

I did answer a similar question before, but perhaps I wasn’t clear. I would highly doubt that dirty clippers could be the cause of hair loss, particularly if it did not cut into the skin by accident. Is your hair loss diffuse, or do your have small patches of hair loss? These are all things one needs to know before assessing the real cause of hair loss. I hope this helps.

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Actor Christopher Walken is Not a Hair Loss Expert – Balding Blog

WalkenThis was sent to me months ago and I forgot to post it!

While he may be an exceptional actor, Christopher Walken is not too bright when it comes to treating hair loss. Read his secret to staving off baldness: Christopher Walken Has Unusual Way To Stop Balding

If anything, I think pulling the hair would stress the follicles and lead to traction alopecia.




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Will a Trichophytic Closure Still Leave a Noticeable Scar if My Hair Is Cut Short? – Hair Loss Information by Dr. William Rassman

Would you generally advise transplanting hair to the temple area where no hair is currently there? I’m thinking this can maximize the chances of a fake look? Am I right?

I read about the trichophytic closure technique — if it only covers 1mm of scar area, then would that leave a NOTICEABLE average of 1-2 mm of scar area still visible if hair is cut short (2 with guard, that is)?

Yes, it may. Scarring is highly variable with different individuals. You can have a doctor with poor surgical skills perform a procedure without a trichophytic closure and still have a great 1mm scar. Or you can have the best surgeon using a trichophytic closure and have a wide noticeable scar. 1-2mm is considered a great scar and it may still be noticeable with a very short hair cut. A #2 guard may hide the 1 to 2mm scar, but this also depends on your hair color, scar color, scalp color, hair coarseness, hair waviness, etc. As you can see, there are many variables.

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My Dermatologist and My Hair Doctor Disagreed About Propecia – Hair Loss Information by Dr. William Rassman

I’m 33. About 6 months ago I went to see a ht doc, and my doctor and dermatologist. The ht transplant doc prescribed propecia and told me to come back in a year, but my doc and the derm would not. My doc said you could see a little of my scalp on top but nothing out of the ordinary. The derm said, along with my family history, that “there are no signs of mpb and your hairline is strong.” But I had bad imflammation, he prescribed Luxiq, a topical steroid, but I have been feeling like I was losing more than normal/thinner than normal. About a month ago, I started the propecia, just to see how it went, because I was nervous about losing anymore.

The inflammation has only gotten worse, and now in the last few days, I am shedding like crazy! My head does not itch, it is just a dull pain/feeling on the vertex. The last few days I lose up at least 50 hairs so easily when styling my hair for just a minute – much, much more than ever before. I’m afraid to even touch it.

So – can you shed on propecia if you arent actually actively losing hair? Does the shedding hint that I actually am losing hair? Also, if I decide now to stop the treatments and follow up again with my derm, will the hair that I’ve shed come back, even after stopping the treatments?

Thanks

I would assume that the hair transplant physician did a miniaturization study to come to the conclusion that you have male pattern balding and that you need Propecia. Eyeballing someone’s scalp is not the equivalent of this. I would make make an appointment with your dermatologist and have him/her recheck you since you are having more problems. I can not tell you what is going on without knowing what your dermatologist is treating with the steroids. Having said that, I would doubt that Propecia is causing your hair loss.

I Get White Hairs When Stressed – Hair Loss Information by Dr. William Rassman

Im 27 yrs old female and when I get stressed I get White hairs not gray. But sometimes I get striped black and white hairs I dont think I have a brain tumor like one blog said and I dont have any med. problems so whats up with the striped hair?

Very interesting. Unfortunately, I have no experience with a person whose hair turns white or gray and is stripped. I have seen stripes of white hair mixed with dark hair. Maybe what you are reporting is something that I should have observed in some of my patients. I don’t have all of the answers and am often humbled by my ignorance.

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