Hair Loss InformationSoy and Propecia – Hair Loss Information – Balding Blog

I came across this web site that says soy and saw palmetto can interact with finasteride. I am wondering if they can potentially exacerbate side effects, as I experienced side effects b/c of Propecia and I was on both of those (and still am on soy).

Also, I’ve heard quercetin, which is found in citrus fruits, broccoli, green tea, red onions, red grapes, etc. utilizes the same enzyme that metabolizes Propecia, thereby increasing serum levels of the drug and leading to potentially more side effects. I also started green tea when I started Propecia. What do you make of this?

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Much of what you are talking about reflects unsubstantiated claims. There have been mentions about soy isoflavones interfering with some medications, but I don’t believe that the connections you referenced are one to one with regard to the side effects. The mechanism of action of saw palmetto is not clearly defined but there is probably an impact on reducing some of the effects of DHT according to at least one reference I read. You can experiment on your own by stopping the soy and seeing if there is any difference (I am assuming that you are experiencing side effects).

Your logic may be flawed with regard to quercetin competing with 5AR. The human body knows how to regulate the byproducts of metabolism and can increase the amount of 5AR if it’s feedback suggested a shortage of it. I am afraid that you are oversimplifying the biochemistry here.

Propecia Contains Lactose – Hair Loss Information by Dr. William Rassman

Hello Doctor, I am lactose intolerant and was about to start taking Propecia when I noticed that it has lactase as an inactive ingredient. And that Merck cant recommend it if you are allergic to “anything” in the drug.

From my understanding, a lot of drugs seem to use lactose monohydrate as a “filler”…but I am trying to evaluate how big a deal it could be. I obviously still eat dairy in every day life (I just take Lactaid with it)…if I dont it gives me stomach aches, but its not like a gluton alergy where you cannot have any period.

In either case, I have not found to many articles about people having serious problems with this, and with the very high numbers of people that are lactose intolerant, it seems like it wouldnt be an issue (especially since it is just an enzyme deficiency). Its easy to say “your alergic to something” so we cant recommend it…but this is basically my only option, and I dont want to just write it off…what do you suggest?

I would (under a doctor’s guidance) give the drug a reasonable course and see if you have GI problems caused by the medication. I’ve got plenty of patients with lactose issues that haven’t reported any problems from the daily Propecia, but I suppose it can depend on how sensitive you are to it.

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Difference Between Telogen Effluvium and Diffuse Alopecia? – Hair Loss Information by Dr. William Rassman

(female) I am very interested to read about a woman on here who had been diagnosed with diffuse alopecia from taking the yasmin birth control pill-I am experiencing the same sort of situation having lost 30/40% of the bulk of my hair during the two yrs I was acutally on yasmin, now, nearly 6 months after quitting the pill I have lost around 65% of the bulk of my hair, the hair loss worsening since stopping.

I would be so grateful if you could clarify-what is the difference between diffuse alopecia and TE? It has been nearly 6 months since the hair on the top of my head has fallen, leaving my scalp very visible under any sort of light-is there frequently this sort of delay in hair regrowth if the problem is TE? I notice in the reply that you comment if all other things have been tested and considered (for me, they have) then you ‘may’ see regrowth within 2-6 months…

Thanks in advance for your response.

Diffuse alopecia means a “uniform hair loss”. The term does not point to a cause. Telogen effluvium refers to a temporary loss of hair that is uniformly lost as it goes into the telogen phase of its hair cycle. Please read the below references, as they discuss the various causes for TE:

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Can Propecia Help My Temples? – Hair Loss Information by Dr. William Rassman

I’m 23 years old now and been on Propecia for 1 year. I been a NW2 since 17 but a year ago I started to have mild thinning around the hairline like an inch in. It took about this whole year but now I’m back on a solid NW2 and it seems to be getting thicker. I know Propecia can work for many years heck there is men on it for 10 years and still fine but my question is…since the temples are very dht sensitive, can Propecica help those too for many years? I wish to remain on a solid NW2 for years to come but I’m afraid that won’t be the case Also I have a weak MPB family history btw so I guess that can help me.

Finasteride will help slow down hair loss throughout the scalp. I do not believe that it works any less in the temples when it is taken before the hair loss is evident. You need to see a doctor and get your problem managed professionally.

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Kaminomoto Hair Tonic – Hair Loss Information – Balding Blog

i have been using kaminomoto hair tonic. i want to know if this is rite product for my hair and i want to use proscar finasteride 5mg. will there be some side affects or not because i hear that there is serious side affects by using proscar finasteride 5mg. pls i want good advice

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I hadn’t heard of this tonic in some time (the name sounds like something I saw for sale decades ago), but I did some quick research and found the ingredients are listed as, “alcohol denat, water, rosemary extract, capsicum frutescens, glycerine, menthol, sophora radix (kujin extract), allantoin, panthenol, pyridoxine HCl, isodonis japonicus (enmeiso extract), glycyrrhetinic acid (kanzo extract), hinokitiol (hinoki extract), neo-takanal, fragrances”.

So in other words, it contains nothing that will help with treating your hair loss. Is it the right product for you? Well, if you’re using it to regrow your hair or halt your hair loss, then no, I think it is not the right product. If you’re using it to line the pockets of the vendors and makers of this tonic, then yes, you’re on the right track.

I’ve written many, many times about potential side effects from finasteride. You shouldn’t be taking 5mg for hair loss anyway — the 1mg will do just fine. You do run a greater risk of side effects with the higher 5mg dosage anyway. My advice is to see a physician rather than treating yourself with hocus pocus tonics that will likely not help.

Hair Loss InformationCan Just One Accutane Pill Cause Hair Loss? – Hair Loss Information – Balding Blog

I was prescribed Accutane for my acne, but I only took one pill before deciding that it wasn’t the course I wanted to take after all. I’m scared that that one pill could have led to my thinning hair. I’ve read stuff that even one dose of finasteride binds to 5AR2 enzymes and the half life to unbind is 30 days! So I’m thinking there’s some similar mechanism in Accutane i.e. just one pill can affect more than just one day…

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Simply put — the answer to your question is “no”. While the mechanism of action for Accutane (isotretinoin) is not known, it is thought to reduce the secretion of sebum. I highly doubt it has any association with the mechanism of action of Propecia (finasteride). Plus, I would doubt that it would cause damage to your hair after taking just one pill (it is not cyanide).

Discuss your concerns with the doctor who prescribed you the medication. Your hair loss is most likely independent of Accutane and you may even benefit from that medication if it was prescribed to you be your physician. It isn’t a guarantee that everyone taking Accutane will see hair loss. Each person reacts to medication differently.

Positive Impacts on Hair Growth? – Hair Loss Information by Dr. William Rassman

Do the following have POSITIVE impacts on hair health?

  1. head massage – No.
  2. other techniques for increased blood flow to head – Nope.
  3. healthy diet, if so what foods are important to eat and which to avoid? – You should have a balanced diet.
  4. use of dandruff shampoos – No, sir.
  5. use of any particular shampoo or conditioner – No impact.
  6. vigorous exercise – No.
  7. any activity that promotes increased cardiovascular health – Nope.
  8. use of dietary supplements (vitamins and minerals) – No impact in moderation.

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Negative Impacts on Hair Growth? – Hair Loss Information by Dr. William Rassman

Do the following NEGATIVELY impact hair growth?

  1. alcohol use – In excess, yes.
  2. marijuana use – Possibly.
  3. tobacco use – Possibly.
  4. high salt diet – I would doubt it.
  5. diet high in preservatives – I don’t know.
  6. high fat diets, red meat – I doubt it, but there are unsubstantiated claims that blame red meat.
  7. use of dietary supplements like multivitamins – No.
  8. over intake of certain vitamins – Yes.

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Merck’s Finasteride Infertility Studies Were Less Than a Year Long – Hair Loss Information by Dr. William Rassman

Hello Doctor .
My wife and I have now been trying to conceive for 12 Month without any luck. I have been taking propecia since almost 4 years now. I did two “spermogram” at 3 month intervals. Results were really different from one period to the other but both time it shows a lack of “motility”. I also read the official Merck reply here on your site regarding this question. Merck did two studies with men age between 19-50 years alors but I have been astonished to see that both time the studies were not longer than 48 weeks, less than a year . Do we have any other “longer” studies done by merck ?

Studies showing the impact on spermatogenis on a 24 month period at least would be to my opinion more relevant.

I look forward for your reply. Thanks and Best regards.

No longer studies that I’m aware of, but I will forward this question to Merck for their reply. In the meantime, you should be discussing this with your doctor who can ask, with more authority, the same question. I did post about Propecia’s link to infertility recently (see here).

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Is Actor Brendan Fraser Balding? – Hair Loss Information by Dr. William Rassman

Hi Doc. Got a quick celebrity question. I’ve heard that brendan fraser is loosing his hair. I’ve seen a lot of photos and to me it does look like his hair line is thinning. Here is a link to some recent photos at the premier for the new mummy.

Photos at Brendan Fraser Film Consortium

There does appear to be considerable thinning behind the frontal hairline from these pictures. The change shown here could be do to the use of concealers, or a treatment period on Propecia or minoxidil (it would be a great result from the medications and I have seen this on occasion, although rare). It could even be a hair weave which has the fullness of body, or it could be a series of hair transplants doing this.

I absolutely think that the after picture with good hair shows his handsome facial characteristics which are blunted by the thinning look of the before photo, making him look almost sickly in appearance. The after picture shows the “sex appeal”, while the before picture probably will not be driving the girls crazy.

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