April 2009 – Page 9 – Balding Blog

April 13, 2009

I Ordered Propecia via the Internet at the First Sign of Hair Loss – Hair Loss Information by Dr. William Rassman

Dear doctors, keep up the super work. This is my story below.

I worked crazy 12-14 hour days for the past 2 years, and I practically skipped my meals, or had them very irregularly. I lost a lot of weight, and looked good in clothes. Essentially I was malnutritioned. But 1 day I woke up, and noticed easily 20-30 strands of hair on my pillow. I dismissed it as normal, and over the next few weeks, it was the same scenario everyday. It still failed to sink into me.. because I was always healthy. I had a friend who laughed at me, and said that I had a receding hairline. But I ignored him, because I have had a very high forehead / high hairline since birth. One day I looked in the mirror and realised to my horror, that YES I was losing my hair. I immediately ordered Propecia thru the internet.

I have been on Propecia for the past 9-10 months, and I have seen a slowing in the loss of hair. However I’m not really sure if there has been any significant re-growth. There are definitely side effects for me. I no longer get ANY morning wood.. and I need to be significantly aroused before I can have any sex. In the past, it wasn’t the case. (Easier to be aroused). Currently I’m a Norwood 2 – 3. (Can see my widows peaks easily.) By doing the frown test, I can see my hairline has receded half an inch, while my sides have receded 1 inch.

Now for the question:
I can see tiny vellus hairs at the part where my hair has receded. Should I attempt to apply Rogaine just along that 1/2 inch area of tiny vellus hair? Or should I continue my Propecia treatment and hope for the best? It’s really quite sad to see my hair go this way.

I thank you for all the help you have rendered all the brothers here. I feel happy that we can find support in your blog. I wish you and your team all the best always.

You can apply Rogaine at the hairline, but I’m not sure it’ll do much good there. Worth a shot, I suppose. Vellus hair does not turn into normal adult terminal hairs.

I really hope you didn’t just order a prescription drug via the Internet without a doctor’s prescription, because that is what it sounds like you did with Propecia. Regardless, regrowth from Propecia doesn’t occur in everyone, but just halting the hair loss is a positive sign. Arousal issues could be from the medication, but I don’t know what other issues you have in your life — it could be age related, stress related, alcohol or substances, etc. I don’t know enough about you, and this is why a doctor’s appointment should be made to discuss these issues (preferably with the same doctor that prescribed you Propecia).

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April 13, 2009

Does Dr Farjo Perform Miniaturization Mapping? – Hair Loss Information by Dr. William Rassman

dear dr farjo,
i live in the UK and have consulted a few transplant drs up to this point- but neither of them could give me a conclusive answer as to whether the hairloss i have experienced is the development of a mature hairline or early stage MPB. (I have minor recession at the corners of my hairline, and am 24 yr old male)

I would be interested to know how you would assess this and do you perform the miniaturization study like dr rassman? as the drs i have consulted so far did not.

thank you

The following response is by UK-based physician Dr. Bessam Farjo:

Response by:

Dr Bessam Farjo
United Kingdom

Well, I start by asking you about your own hair loss history and its progression. I then obtain a thorough family history to assess the likelihood of progressive hair loss. Unfortunately the younger you are the harder it is to be accurate. An examination of your entire scalp follows to see if you are losing it in a genetic pattern. I may even suggest a genetic test to help predict your future loss but that is not definitive either.

I can certainly assess your miniaturisation like Dr Rassman. One of the other video microscopes I have is also capable of measuring hair calibre and has the software to compile such data.

A genetic test to assess responsiveness to finasteride is in development and I will be able to provide that when ready.

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April 13, 2009

Can Shampoo Harm Hair? – Hair Loss Information by Dr. William Rassman

You’ve said that daily shampooing of hair won’t cause hair loss unless we wash too rigorously. Disregard the physical aspects of washing. Can the chemicals in shampoo be affecting our hair follicles? I know that hair is “dead” when it grows out of the skin, but I’m concerned our hair follicles are shallow enough that the shampoo may be affecting them. Although if this were the case, perhaps a lot more women would have the same type of hair loss as men.

Sorry, but you’re completely off base with this. Shampoo itself has nothing to do with hair loss… absolutely nothing if it is a good commercial shampoo.

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April 13, 2009

Can Propecia Interfere with My 18 Year Old Son’s Genitalia Growth? – Balding Blog

I’d like to know if finasteride is safe for an 18 year old boy. Can it interfere with a possible genitalia growth spurt that I’ve been told can occur even after complete bone growth up to age 20 or 21? My son appears to have male pattern baldness, so his Dermatologist has put him on the drug, but his Endocrinologist advises against it. My son doesn’t want to lose his hair so he’s taking Propecia, but doesn’t know about the other possible problem. It’s not something I want him worrying about unless the drug can really interfere with genitalia growth, in which case he should know so he can decide for himself whether or not to take the drug. Please advise.

Propecia (finasteride 1mg) is safe for 18 year olds and this medication is not known to retard genitalia development in young men. The 5-year effectiveness and safety study submitted to the FDA included men aged 18 to 41 years old. He is correct that to hold on to his hair, this is the best approach.

April 10, 2009

Can You Preserve Hairs for Transplanting Later? – Hair Loss Information – Balding Blog

Why can’t you transplant hair from one person to another? if the hair is exactly the same colour and close enough the same texture is it possible to do this? Also, on the same note can hairs remove during a procedure be preserved or do they have to be put into a head straight away? honestly it would be a great idea, people with generously thick hair “sell” their hair to you and then you could probably charge 3 times that amount to put it into someone elses head, it would make lots of money.

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There is a lot of experimentation occurring, but nothing that exists at this time. Hair grafts start dying at about 8 hours out of the body while kept in ideal conditions like iced Ringer’s solution at about 34 degrees Fahrenheit. The death rate for grafts occurs at a rate of about 1% per hour after the 8 hour period. In 24 hours, there will be 24% death rate of grafts, 48% at 48 hours etc.

Hair follicles are organs, and like with a kidney, liver, or heart transplant, these organs also have limited times to get them into their new and final resting place. You would have to take anti-rejection medication for the rest of your life if you used anybody’s hair organ other than your own and the risks of these drugs are high for death — a risk perhaps worth taking for a heart or liver, but for hair? No way. These medications can lead to other health complications, and since a hair transplant isn’t exactly a lifesaving procedure (like a heart transplant would be), the end doesn’t justify the means.

April 10, 2009

Grapefruit Juice and Finasteride/Dutasteride Absorption – Hair Loss Information – Balding Blog

Dear Doctor:

This is in response to a post that I saw regarding grapefuit juice and Propecia/Avodart absorption. Grapefruit juice inhibits the Cytochrome P-450 intestinal enzyme CYP3A4. It does not affect the hepatic enzyme apparently. Dutasteride is metabolized extensively by this enzyme. The serum level of any CYP3A4 substrate, such as Dutasteride, will be elevated in the presence of GF juice. Additionally, grapefruit juice takes quite some time to leave the body, so it’s effect is cumulative. If someone drinks 1 glass a day for 5 days, CYP3A4 will be significantly reduced. Additionally, one 8-oz glass of grapefruit juice inhibits CYP3A4 as much as 2-3 double strength glasses, so you don’t need much. Ketoconazole is also a very potent CYP3A4 inhibitor. Now, I am sure most readers would not be against elevated serum levels of Dutasteride/Finasteride as the effects of dutasteride (at least) is dose-dependent. However, many other drugs such as antivirals, statin drugs, antihypertensives, antiseizure medications, and many allergy medications are also CYp3A4 substrates. Elevated serum levels of these drugs can prove deadly, so as a general rule, patients should check with their doctors regarding any drug/food interaction.

Just my 2 1/4 cents. Thanks!

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Thanks for the information. There are some medications that do not do well with grapefruit juices, but here some other links to explore about this —

And there’s more links in a previous blog post here.

April 10, 2009

Hair Loss InformationCan Water Cause Hair Loss? – Hair Loss Information – Balding Blog

Hey

I have a question and would be glad to get a response.

Can the kind of water I use cause baldness? I hear that Chlorine water and the , metals inside the water we shower in can cause baldness.

If so, can applying small amounts of water everyday increase baldness?

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The answer is simply: NO. Water is good for you, but you can be poisoned with salt water or chlorine water, not the metals in the shower water in the United States.

April 10, 2009

One Propecia in the Morning, One Propecia at Night? – Hair Loss Information by Dr. William Rassman

Dear Dr. Rassman,

I know there is no standardized evidence to say one way or another, but in your opinion is 2 mg of Propecia (1 mg taken in the morning, 1 mg taken at night) more effective at preventing hairloss than 1 mg Propecia?

The reason I ask is I have been taking 2 mg Propecia daily for almost 3 years now, and have started to experience “clumpy” semen and painful ejaculation. I am thinking this is due to a side effect of Propecia. I am kind of in a dilemma now because I don’t know if my fight against hairloss will be affected by cutting down the Propecia to 1 mg or altogether. I am 26 yrs old and single so hair is very important to me.

Thanks Dr. Rassman!

I would reduce the dose of Propecia to 1mg taken in the mornings. The higher the dose, the more side effects you are likely to see. The 1mg dose has been shown to be just as effective as higher doses in the formal studies of drug dosing done by the manufacturer. I recently saw a patient with a similar complaint, and he halved the dose and the side effects went away. He was taking 1mg and reduced it to half a pill of Propecia, which has been reported to be about 80% as effective (0.5mg vs 1mg). In your case, you’re taking too much of the medication to begin with. 1mg a day is fine.

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April 10, 2009

Images for “Intercytex Announces ICX-TRC Phase 2 Results” – Balding Blog

This is a continuation to last week’s post, Intercytex Announces ICX-TRC Phase 2 Results by Dr. Bessam Farjo. He had included these images with the text of his original article, but I didn’t have captions for them so I held them back until they could be presented in the proper context. The captions and images were provided by Dr. Farjo. Click to enlarge:

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Baseline MacroPhoto of tattooed study area 1 week after injections

MacroPhoto of tattooed study area prior to cell injections

Preparing multiplied cells in solution in GMP facility

Cell solution ready to be drawn up in syringe

Diagrammatic representation of the ICX-TRC trial concept

Cells Injected into volunteer

Top left to bottom right: Cells multiplying in culture day 0 to day 14

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Learn more about the author of this article, Dr. Bessam Farjo, on his BaldingBlog profile or at his website.

April 10, 2009

Hair Pulled Out in a Fight — What Can I Do? – Hair Loss Information by Dr. William Rassman

I was in a fight in high school, and my hair was pulled out in the back of my head. As a result my hair has never grown back correctly. My hair isn’t bald but short in this one spot. My mother told me about hair growth treatments in the salon what do you suggest.

I would need to see it. Hair transplantation works well for missing or short hairs and could be a solution for you. Generally, hair that is pulled out once will return almost 100% of the time, but if you were treated with strong chemicals to try to bring it back, the chemicals may have burned/damaged the hair follicles enough to make them weak.

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