January 2010 – Page 6

January 15, 2010

Hair Cloning and Organ Regeneration – Hair Loss Information – Balding Blog

Bald heads I have seen some videos taken from CBS 60 minutes and another CBS news release that outlines an approach to growing organ parts (see here and here). The challenge of growing an entire organ like hair (which is a complete organ containing skin, glands, fat, nerves, blood vessels, stem cells and special hair growing cells) is more difficult than these video examples of finger tip and heart valve growth. Much of this research has been funded by the U.S. government and military and one has to be careful about taking such early studies and expanding on its greater meaning.

A number of readers recently pointed me to a press release apparently sent out by Drs. Hitzig and Cooley proclaiming they’ve successfully cloned hair using a special powder called MatriStem MicroMatrix. Here’s a part of the press release:

MatriStem MicroMatrix, a product of regenerative medicine innovator, ACell, Inc., is a wound healing powder that promotes healing and tissue growth and has now proven to help regenerate hair in the donor and recipient regions of hair transplant patients. While intended for diabetic ulcers, venous ulcers, pressure ulcers, traumatic wounds, second degree burns, surgical wounds (donor sites/grafts) and trauma wounds, Hitzig and Cooley have found that its properties offer a broader scope of treatment, including hair cloning.

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There are some very early ideas on how this might work with hair, but there is no solid research available to support the hair claims. The press release is a bit sensationally written on the hair side, and I’d suspect this was sent out by an overzealous PR agency with a flair for the dramatic, rather than this being a case of these doctors claiming to do something that can’t be done with any consistency.

You can read the full text of the PR here.

Photo source: Associated Press

January 15, 2010

My Boyfriend’s Hair Transplant Didn’t Grow Back After Shaving His Head! – Hair Loss Information – Balding Blog

Dear Dr. Rassman,
My boyfriend had a FUE operation using hair both from the back of his head and his chest (all together about 1200 follicular) to cover the toothbrush look of his previous punch graft operations on the frontal part of his head. After less than six months the result was so great that everybody was under the impression that with another operation or two on the crown part of his head he would have a 70 to 80 percent of his previous normal hair days look back.

Approximately eight months after the operation he completely shaved his head with a Gillette Fusion razor with the hope that his new and old hair may look thicker and more ready for the next operation, but to everybody’s surprise (not to mention his horror) only 40 to 50 percent of his newly transplanted hair has grown back (after two and half months now) and the look of his frontal head now can be described as balding with previous plugs being visible again. I would really appreciate your comment and/or advice on the matter.

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Razor FUE is not a perfect technique and it has a higher failure rate than the standard strip surgery, as the follicular units are often stripped of fat at the bottom of the grafts. Also, body hair transplants do not work to my satisfaction, because body hair does not grow the way scalp hair does. Body hairs do not grow continuously like scalp hair, as it is in its resting phase much longer. That is why most doctors do not perform body hair transplants; it’s not because body hair transplant is difficult.

Aside from these generalizations, I would only be guessing as to what caused the hair to not regrow after shaving it. And providing a guess would not be fair to you, your boyfriend, and even the surgeon. He needs to go back to his surgeon and follow up with this issue.

January 15, 2010

When I Get Drunk, I Have Less Hair Loss – Balding Blog

Hello Dr. Rassman,

I am a 35 year old male with a Norwood pattern II hairline. I have tried Propecia and Rogaine with no success.

I recently made an interesting observation about my rate of hair loss that has me perplexed, but hopeful. Ever since my hair loss began serveral years ago, I have noticeed a very consistent 40-60 hairs on the shower floor after towel drying my hair following my morning shower. Interestingly, however, on days when I have consumed a large amount of alcohol the night before (especially multiple nights in a row) I notice an astonishing decrease in the number of hairs lost (sometimes the total drops to as low as 5). Based on my knowledge of the science behind hair loss, it initially seemed highly unlikely that there could be a connection here – but I can no longer argue with the facts. The decrease happens every time.

Clearly getting drunk every night is not a desirable solution to my hair loss problem – so I’m hoping you can help me determine what the mechanism of action might be – and if there are any other ways of achieving the same result.

Beer can
I’m not going to suggest becoming an alcoholic to fight your hair loss, but I guess seeing less hair on the floor is a good thing. What you’re describing really makes no sense to me, though. There’s no basis for a relationship between a night of drinking and seeing less hair loss the next day. I wish I could pinpoint a connection for you, but I think we’re equally confused about this.

Maybe you just can’t count hairs accurately in the drain when you are hungover?

January 15, 2010

Taking Finasteride and Giving Blood – Balding Blog

Hello Doctor,

With all of the terrible things happening in the world, I would like to give blood. However, I have been told that finasteride is not allowed in blood transfusions.

Are there any organizations for whom I can donate blood or plasma or platelets that can be used? It seems an awful shame that I can’t give blood while on proscar.

It seems as though I could stop taking it for a few days, give blood and then start up again, right? Or would it be possible to tag the blood as having finasteride and only transfuse it into male patients?

If you’re taking finasteride, blood donation is bad for recipient women who are pregnant due to the risk of birth defects… and that is why it is banned for blood donors. I don’t know about tagging the blood in the donation process. Finasteride users are supposed to wait at least a month after the last dose and dutasteride users should wait at least 6 months before donating blood.

There are other medications that take even longer, such as severe psoriasis treatment acitretin, which has a 3 year wait before you should give blood… and etretinate, which eliminates you from giving blood entirely.

January 15, 2010

My Hair Started Rapidly Thinning in My Mid-40s – Balding Blog

Hi Doctor

I am male age 47 and my hair has been thinning very very rapidly over the last 5 months. Prior to this I just had normal daily hair loss which was unnoticeable. Is this normal at age 47 and also do you think propecia will grow back my hair given that i’m 47

Thank you

I am unclear as to why you are losing your hair so rapidly. What you’re describing is not usual, but certainly male pattern baldness is a possibility. Medications such as Propecia may help, but that is ONLY if you have androgenic (male pattern) balding. You need a good examination and a diagnosis before thinking of treatment options.

January 14, 2010

Rogaine Half-Life? – Balding Blog

Doc,

I read that Rogaine has a half-life of about 22 hours in skin. Assuming you have no side effects from applying it all at once, could you apply double the recommended amount once per day and have the same effect?

Rogaine Minoxidil was originally a not-that-great oral high blood pressure medication called Loniten. The results varied in the treatment of high blood pressure and eventually the medication was turned into a topical after the hair growth side effect was noticed. The drug stays in the plasma for about a 4 hour half life, but on the skin it stays much longer with slow absorption suggesting that once a day application may be satisfactory.

I can not comment on the official use of twice a day application to the scalp, but clearly more of it will be used and sold with twice a day applications. If you double the dose and apply it once a day, the drop in blood pressure side effect becomes more prevalent.

January 14, 2010

Is Elocon Safe to Use on Transplanted Hair? – Hair Loss Information by Dr. William Rassman

Hello Doctor

this Elocon lotion is supposed to be massaged on the scalp topically in order to fight seb derm (a few drops per application, once a day for a few days)

Is it safe to use it on
a ) transplanted hair
b ) healthy non transplanted hair

Is there a hair loss risk , and if so , permanent or temporary ?

Thank you in advance

Elocon Elocon (mometasone) is a topical steroid and there is plenty of information on the Drugs.com site. It specifically states that Elocon can cause “swollen hair follicles”. Does this mean that you may lose hair? Well, the term swollen hair follicles is not one I am familiar with. Steroids applied to an area of hair loss can accelerate hair loss.

If I can provide some help it is that healthy non-transplanted hair is equal to transplanted hair. It is YOUR hair! I mean, that is one reason people get hair transplants and not wigs! So if a drug can harm your healthy hair, it can also harm your transplanted hair.

In the end, Elocon is a medication that needs to be prescribed by a physician. The use of topical steroids can be dangerous when not controlled by a doctor, so you need to discuss with your physician the risks and benefits of using such medication. Please do not read this as my trying to brush you off or not address your issues. My role here is limited and I give general opinions.

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January 14, 2010

Is 15% Minoxidil Too Much? – Hair Loss Information by Dr. William Rassman

Is it okay to use 15% minoxidil, or is it too much for a good thing?

5% minoxidil is the recommended dose and I’d suspect that 15% would be a bit much, possibly causing more side effects (fainting from drops in blood pressure, more skin reactions, etc).

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January 14, 2010

I Don’t Trust My Doctor After My Hair Transplant Consultation – Hair Loss Information by Dr. William Rassman

I am planning to undergo hair transplant. I have consulted a doctor in Delhi (India). He has suggested that I will require 3500 grafts. He says he will perform the hair transplant from 9:30 AM to 5:00 PM. My concern is: Can he place 3500 grafts in one session in one session or is he just cheating me? Because placing 3500 grafts skillfully might require more time.

Please advise whether 3500 grafts can be placed in one session.

It would be rare for an Indian to have enough density to allow for even 2500 grafts, as the typical Indian has a much lower density than Caucasians (who might yield 3500 grafts). With the time he quoted, it would be unusual for that to occur as well. In the hands of experienced hair transplant surgeons in the US like me, it generally takes 7-8 hours. Plus, you are questioning his honesty and that alone should raise a flag.

To be sure that he can do this procedure, ask to meet other patients who have had this done so you can see the results of that work. There is no substitute for meeting and seeing patients who have experienced this.

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January 14, 2010

Does Hair Miniaturize While It is Growing? – Hair Loss Information by Dr. William Rassman

Question about ministurization. Can hair miniturize throughout growth or does it only miniturize after previous hair has fallen out. The hair that I lose I find some of them are really thick while some of them are thick but are thin near the root – is this miniturization? Thanks

Balding men lose mostly miniaturized (thinner) hairs, but they do lose normal thickness hairs. I believe it happens within the anagen (growth) phase and during the telogen (rest) phase of the hair cycle, but things are not always clear cut. Some hairs are partially miniaturized and can look thick, and the hairs you are looking at in a point in time may not be found again when looking anew. Usually the hair follicle that stops producing hairs will make the root of the hairs shrink and eventually the shaft of the hairs would also shrink (in a continuum).

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