Hair Loss InformationBlindly Following Hair Loss Treatment Companies – Hair Loss Information – Balding Blog

I honestly think you have been somewhat indifferent towards Histogen’s potential. As researchers have recently discovered, the baldness gene affects WTN7 pathway. Histogen stimulates this pathway to produce new folicles and thicken exisiting ones. Obviously, there is a connection. The only affirmative emails you respond to involve propecia. I have been taking propecia for 2 years and I have not had any improvements with my hair. In fact, I have significantly lost more hair. Now you’ll probably say, it’s keeping what you have, but that’s BS. It isn’t effective because it isn’t addressing the real issue of hair miniturization which has been recently connected to WNT7 pathways (Dr. Christiano, Columbia)

Now I can understand why you would want to downplay this company because if it does go to market within 3-5 yrs in Asia, hair transplant surgeons will not benefit financially as much as they have in the past. In fact, nurse practitioners would be able to treat patients. At this point, I will no longer be a reader of your blog because I find your replies to be completely boring and repetative. Maybe you should invest some of the kickbacks you’ve received from Merck into a Histogen if you really wanted to see a viable hair growth treatment come to market

Good Bye and Good Luck

Block Quote

For those who freely read on, my position on hair loss has remained constant. There is no cure for hair loss and Propecia is certainly not a cure (though it helps treat hair loss in most men). I recently wrote about the discovery of the hair loss gene pathway you are referring to, but if you read on, it is not about male pattern baldness. As quoted by Dr. Christiano herself, “It is important to note that while these two conditions share the same physiologic process, the gene we discovered for hereditary hypotrichosis does not explain the complex process of male pattern baldness.

In the end, I am happy that there is research being carried out to find a cure. I care about patients and if I was actively trying to steer people to my surgical practice why would I bother telling them to take a pill? Why would I spend time answering questions on this site every day that have nothing to do with directing patients to surgery? Your logic is full of flaws and you come across as an angry, desperate person. You are misdirecting your anger at me, possibly because of your impatience at these cloning companies and their moving timelines. Should I be sad that I do not receive any kickbacks by Merck or Histogen or Dr Christiano or any other companies or individuals? I’ve already stated my connections (or lack thereof) to Merck. They make a medication that works to treat hair loss. It is proven safe and effective. The rest is all conjecture.

Lastly, I am sorry that you find my comments to be repetitive, but at least they are consistent! So thanks for your insightful comments and we will miss you here!

Hair Loss InformationRogaine, Unda Drops, and Alopecia? – Hair Loss Information – Balding Blog

(female) Hello.
I’ve been diagnosed with AA. Have tried several “remedies”. Most recently began using the Unda drops, 9, 40 and 243. I actually, for the first time in 3 years so a marked decrease in shedding and my hair felt better over all. Recently though, (2-3 weeks ago) I began using Rogain 5% as recommended by my dermatologist. nearly three weeks into it I’m seeing a huge amount of shedding. more than I’ve ever experienced. My fear is that the rogaine will not work and the shedding will continue at this rate.

question. Can Rogaine make matters worse? If my stress factor allows, how long should I remain on the rogaine to see results and how long can I expect this increased shedding to continue? I’m so tempted to just throw in the towel and just continue the unda drops and biotin hair/skin/nail formula.

Thank you

Block Quote

UndaUnda drops are homeopathic remedies and I am not a homeopathic doctor. I do not know the utility of what you are using, but if something worked for you why would you want to do something different? Many men and women report initial loss or shedding of hair after starting Rogaine (minoxidil) in the first month of its use, but the shedding should stop unless there are other underlying issues not related to the medication. Generally you need to use Rogaine for a minimum of 8 to 12 months before seeing the effects.

Rogaine may work for alopecia areata or androgenic alopecia (I’m not sure which you meant by your diagnosis of “AA”). It does grow hair, but I doubt it will grow back the hair you once had and if the problem is underlying alopecia areata, then you should be under the treatment by a good dermatologist who can often help with the process.

Hair Loss InformationMy Brother Got Mom’s Family Hair Loss Genes – Hair Loss Information – Balding Blog

Hi,

My brother is in his early 20’s and has begun losing his hair. He has had inherited hair from my mum’s side of the family, lighter and thinner since he was born. My mum’s side, it is common for the males to bald early. I on the other hand have always had thick and really dark hair from my fathers side of the family. My fathers side does not begin to thin until in their 40’s.

I’m curious as to if I will bald early as well, or is it less likely to happen until later because I have always had my fathers hair.

Block Quote

DiceI do not know for sure when you’ll go bald. It is commonly thought that genetic balding tends to be inherited from the mother’s side, but this is not a definite rule. You cannot predict hair loss on mother/father/family history alone. You can expect nearly a 50/50 chance of inheriting from one side or the other, like a roll of the dice. It might actually be 52/48 in favor of the mother’s side, but it is close enough to not rule the father’s side out completely.

Hair Loss InformationHair Thinning Under Harsh Light? – Hair Loss Information – Balding Blog

Hey,

Your blog is very helpful has recently ive been concerned about my hair. I’m 18, and ive always had a Norwood #2 hairline, its never been a straight hairline. I have thick hair, but its very light, hairdressers etc always say its so thick. I realise this doesnt mean your not going bald. But when I look under light in my bathroom, pretty strong light, or just look at my hair under any reasonably strong light, i can see my scalp in a line that zig zags slightly from my crown to my hairline, but when it reaches my hairline its thin in a patch. You cant see it when its not exposed to strong light really, maybe the odd weak spot. I dont really notice that many hairs, but now that I’m paranoid about going bald i notice just about every hair i lose. My father has black hair unlike mine, and his hairline is pretty similar to mine, my grandfather on my mothers side, and my uncle are the only ones that displayed signs of male pattern baldness, but they didn’t get it till they were well into their 40s/50s.

So my question is, is it common for people with fair hair to see their scalp when under strong light, or sun light. Or can MPB be the reason for this?

Block Quote

LightMale pattern balding could be a cause for what you’re seeing, but what you’re describing is something commonly seen under harsh, direct, or bright lights. Lighting can make any hair appear to be thinner than it is, and if your hair is fine, the problem would even be more prominent.

I wouldn’t be too concerned about this, but if you see a doctor for it be sure to have your scalp mapped for miniaturization so you can actually have a metric to go back and look at in a follow-up visit.

Hair Loss InformationIs It Reasonable to Think Better Hair Drugs Will Be Available This Decade? – Hair Loss Information – Balding Blog

Dear Dr.,

Thanks always for devoting your time to the public with this forum. I notice you’ve been getting swamped with questions about a cloning cure (i.e. a class 7 bald person having a teen-age head of hair again), and people don’t seem to want to accept such a thing is so many years away. I was wondering if it’s more realistic to speculate: for those of us in our early 30’s who’ve preserved most of our hair and reversed some thinning with Propecia, is it reasonable to think a better pharmaceutical for holding on to what we’ve got will come out at some point this decade?

Thank you

Block Quote

There are drugs in the pipeline for hair loss, but the real question is which, if any, will make it through the investigative and FDA process. It must be proven to be safe and effective at doing what the manufacturer will claim. So I suppose it is reasonable to assume (or at least hope) something will come out eventually, but I couldn’t begin to guess at how much better it will be than what is available now. Keep your fingers crossed.

Hair Loss InformationI Had a Negative Result with My HairDX for Finasteride Response – Hair Loss Information – Balding Blog

Hi…Thanks a lot for this perfect blog that answered many questions that concerns hair loss and balding. I had a HairDX test for Finasteride response and my score of CAG was 24. The dermatologist who did the test told me that I have a negative result regarding finasteride response.

1- What do you think of Hairdx test regarding F.R.?
2- Do you think I should take finasteride though I got CAG of 24 ?

Thanks

Block Quote

HairDXI do think the HairDX for Finasteride Response test is a good idea, but it can open people up to the idea of taking medication when it is not necessary. Just because the test tells you that your response to finasteride would be good, it doesn’t mean you should automatically get on the drug if you’re not experiencing hair loss. In your case, I don’t even know if you have any degree of balding. Do you have a full head of hair and afraid of going bald or are you already seeing hair loss? If you are bald or have definite signs of balding, then what do you have to lose by taking finasteride regardless of the CAG score? Were you prepared to not take finasteride (Propecia) if the test was negative?

In any case, it is something that needs to be discussed with your doctor who knows you better than I do, as our communication has been limited to an email. If your dermatologist told you the result was negative, perhaps he/she meant you aren’t likely to have great success from the medication. It is worth noting though that you may still see some beneficial response from finasteride with a CAG score of 24. According to HairDX, “Scientists discovered that among men that had the best response to Finasteride approximately 70% had a CAG score below 22 while among men that had a subtle response to Finasteride approximately 70% had a CAG score above 22.

Hair Loss InformationAzelaic Acid as DHT Inhibitor? – Hair Loss Information – Balding Blog

Dr R

Do you have any opinion on Azelaic acid as a dht inhibitor when used topically by itself or in minoxidil tandem?

Thanks

Block Quote

I do not think there is real evidence that azelaic acid inhibits DHT or works for genetic balding. I am aware that there was a study which was published in 1988 (22 years ago) titled, “Inhibition of 5α-reductase activity in human skin by zinc and azelaic acid“. The testing was not carried out in humans, but in a test tube, and the information is floating around on the Internet (our everyday source of good solid medical information *note sarcasm*).

Aside from this study, I do not know of any other information with regards to azelaic acid and its “theoretical” treatment for balding, yet the legend of one decades-old study will propagate down the immortal path of the internet. For further reading and other physician opinions on this, take a look at this post from a few years back.

Hair Loss InformationCould I Trade My Design Services for a Hair Transplant? – Hair Loss Information – Balding Blog

my situation is – I’m a 28 year old male. I’ve been balding since i was about 21. i’ve been using rogain with pretty good success but in the last year it seems like it just stopped working and i’m developing a pretty noticable bald spot about 3″ in diameter. I’m going to try out propecia and see how that goes. that said if it doesn’t regain enough hair i would really like to get a transplant to sturdy things up in the back. my problem is the cost. i just graduated college and really don’t have much money, but my degree was in motion graphics and i was wondering how receptive transplant doctors would be to do trade for service, doing instructional videos, info graphics or graphic design…is it worth asking?

Block Quote

HandshakeA trade, in these recessionary times, is difficult. The recession has impacted all forms of cosmetic surgery and hair transplantation is no different. I suppose it is worth a shot if you want to try contacting various clinics, but I wouldn’t expect trading design services for cosmetic surgery to be a tantalizing offer amongst surgeons. It wouldn’t hurt to ask, though.

Give the Propecia a try (or to save money, ask your doctor for a prescription for the generic 5mg finasteride and cut the pills into 4 pieces).

Hair Loss InformationSkin Atrophy from Oral Spironolactone? – Hair Loss Information – Balding Blog

I am a 33 year old woman with a diagnosis of AGA. I have found out that skin atrophy is a very rare side effect of oral spironolactone, one which I am experiencing on my facial skin. This is frustrating as spiro is definately working for me. Do you think topical spiro would have the same effect? Also, it seems Cyproterone Acetate can have the same effect so that isn’t an option for me. What do you think of trying Bicalutamide, as it is a non-steroidal antiandrogen? Many thanks.

Block Quote

I wish I could offer some real help, but I don’t know much about the side effect risks of spironolactone beyond what I have read, as I do not prescribe it (or the other medications you mentioned). Spironolactone is a prescription medication, and as such if you’re seeing skin irritation you should immediately notify your prescribing doctor about this.

Cyproterone acetate lists hair loss as a rare side effect (as possible with many medications), but bicalutamide has hair loss listed as a common side effect, so I don’t know why you’d take that as a hair loss treatment.

Hair Loss InformationHave You Become Pessimistic About Propecia for Frontal Hair Loss? – Hair Loss Information – Balding Blog

Dear Dr Rassman,
In your last post you wrote the following in regards propecia.. “It does not work for frontal hair loss in most instances other than possibly slowing the process down, but is it the only real medication to address what you are going through”. However in December 2005 you wrote that “Propecia slows or stops hair loss throughout the head”.

I was just wondering if in the intervening years you have become more pessimistic about the effectiveness of Propecia on frontal hair loss?

Regards

Block Quote

I’ve not become pessimistic about Propecia. I have seen a few cases where the drug has reversed frontal hair loss to some degree (regrew hair), but it is not common. What is common is that this drug can slow or stop frontal hair loss, and stabilization of hair loss is a real benefit for those who are actively losing hair.