Hair Loss InformationReader Says All Effective Hair Loss Treatments Are Potential Carcinogens – Hair Loss Information – Balding Blog

I hypothesise that ALL effective hair loss treatments are potentially carcinogenic in vulnerable individuals. Literally ALL of the factors which are being upregulated to result in HAIR GROWTH, are also factors which are all upregulated in CANCER.

Think about it, Chemotherapy often results in hair loss. Why is this? It is because it is doing the exact opposite to what Hair growth treatments are doing. For hair growth to occur there has to be complex release of various substances, and cell proliferation. On a simplistic level (and there is sooo much more to it), cell proliferation is going to increase the chance of carcinogenic cells developing. Chemotherapy causes CELL SENESCENCE (cell death) which is why the hair falls out. To cause cell senescence various substances, growth factors, etc have to be DOWN REGULATED. These are the very same substances which are UPREGULATED in hair treatments.

eg. Minoxidil: Minoxidil is a potassium (K+) channel opener. The opening of K+ channels causes cell proliferation. Role of Voltage-gated Potassium Channels in Cancer

Laser Helmet – works by opening K+ channels. Spiro is especially lethal – Oestrogen agonist in breast. Tumours in rats. Upregulation of ALL the factors linked with cancer and what helps it proliferate, eg VEGF, EGF, FGF, MMP, and on and on.

Activation of SRC Tyrosine Kinase — From wiki: Tyrosine kinases add phosphate groups to the amino acid tyrosine in the target protein. They can cause cancer by turning the receptor permanently on (constitutively), even without signals from outside the cell. And specifically SRC Tyrosine Kinase.

What are your thoughts on the cancer – artificially induced hair growth link?

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Life has its risks. Do you know how much radiation you get when you fly across the country in a commercial aircraft (see here)? Regular flights may increase the risks of a variety of cancers, but if your quality of life means that to bond with your family you must fly to the other coast, would you rather stay safe and lock yourself in the basement where the radiation levels are much safer?

We all have decisions in life, and with regard to hair, the various treatments available to prevent or reverse hair loss have not been shown to be carcinogenic. It’s your choice!

Hair Loss InformationIn the News – Female Hair Loss Causes – Hair Loss Information – Balding Blog

Snippet from the article:

In most cases, the cause is a genetic condition called androgenic alopecia, which is when hair follicles shrink because of a loss of estrogen and/or increased sensitivity to testosterone. Unlike men, who tend to experience androgenic alopecia as receding hairlines, women generally get thinning at the temples and the tops of their heads.

Once it starts, it usually gets worse, so it’s best to seek treatment earlier on when there’s more hair to save, Redmond said. Androgenic alopecia strikes some 25 percent of women in their 20s and 30s, and more than half of women over 45, when estrogen levels fall, he said.

Other possible, though rarer, causes of hair loss include alopecia areata, an autoimmune disorder in which the body attacks the hair follicles, causing patchy round bald spots. It affects less than 1 percent of the population and typically appears in the teen or young adult years.

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Read the full text at Chicago Tribune — Why do women sometimes lose their hair?

These types of articles get published by a major newspaper every other month or so, and while they’re good reminders about the causes of female hair loss, they don’t offer any new solutions. There are so many possible causes of hair loss in women that it’s difficult to determine why you’re thinning at first glance (unlike men, which have genetics to thank in the great majority of cases). There’s a partial list of those possible causes here.

Hair Loss InformationIn the News – Claims of Severe Side Effects from Propecia – Hair Loss Information – Balding Blog

Snippet from the article:

Young men could be risking their sexual health by taking a commonly used anti-baldness drug, claim some doctors. They say finasteride, sold in the UK as Propecia, can cause serious side effects and isn’t adequately labelled.

A quarter of men in their 20s show signs of male pattern baldness, with six and a half million males in the UK affected. Propecia manufacturer Merck says it continually monitors the drug’s safety and has updated the label.

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Read the full story at BBC — Baldness drug Propecia ‘risking men’s sexual health’

PropeciaI always worry when a single case is put forth as a typical example of a problem. I do not doubt this young man could’ve seen some side effects, but I would think that this is a very rare example if it is true. I do doubt the long term impotence reported, however. Propecia has a half life of 4-5 hours, which means it is out of the blood stream in a day. Tissue fixation of the drug may last for up to a week, but by then, all of the effects of the drug should be gone. Unfortunately, the report gives us little insights into objective evidence for the ED that doctors would explore, such as nocturnal penile tumescence studies, to substantiate if the problem is real or psychological.

I’ve received a lot of emails about this article already, so I know it’s making the rounds. The problem for all those interested in finasteride is that these stories become viral on the internet, resulting in waves of panic for those considering the decision to take it. We each have choices in our lives, and the risks vs the value of such a drug is a decision each of us should make.

For what it’s worth, the young man in the article did say that the drug reduced his hair loss. I am not suggesting that it is worth losing your sexuality to keep your hair, but there may be more to this story than the article seems to want to point out. As I’ve mentioned before, one of my sons is on Propecia and his hair loss stopped (and even reversed a little) since he started to take it.

Hair Loss InformationLaser Hair Therapy Study from ISHRS Meeting – Hair Loss Information – Balding Blog

ISHRSI was flipping through the current Nov/Dec issue of the Hair Transplant Forum International (a print newsletter for the hair transplant industry) and wanted to share something I read. Dr. Paco Jimenez, the co-editor of the Forum, reviewed three oral presentations from the International Society of Hair Restoration Surgery (ISHRS) meeting in Boston a couple months back. His brief review of Dr. Hugh Rushton’s presentation on the efficacy of the laser hair comb therapy caught my attention.

Dr. Jimenez writes, “In this study Dr. Rushton found no differences between the laser treated side and the control side regarding length, density, and diameter of the hairs. The interesting aspect of this study is that I believe it to be the first well-designed blinded study I have come across in which the methods used for hair analysis and the hair counting could not be called into question.

It is important to call a spade a spade and with good science behind it, that is the best we can do.

Hair Loss InformationHair Quality and Density – Hair Loss Information – Balding Blog

Hi. Enjoy reading your blog here.

29 year old male that is noticing what appears to be thinning in the crown area. I have very long hair, shoulder length. (not cut in a few years) Not really bad thinning yet, or necessarily noticeable to others than me… but certainly seem to have less hair there than on the sides of my head. Not crazy.

What I’m trying to figure out is hair quality. From the thinning area I have plenty of hairs that are every bit as thick as the stuff on the side of my head. In fact, some of them are thicker. A few thinner, but not many.

Would it make sense that hair quality could be similar… yet one area has much more coverage? I should think that I would find more evidence of miniaturized hairs in my thinner area. Maybe I’m just missing them?

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I’m a little confused by your question, but if you are searching for a diagnosis you should see a doctor who can examine you and even conduct a miniaturization study at various locations on your scalp, as well as a hair bulk measurement if your doctor has the tool available.

But you even state that your thinning is “not really bad” and not “necessarily noticeable to others”, so anything is a possibility. Some areas of the scalp may have less hair density and more miniaturization. That in itself may be what you are seeing.

Hair Loss InformationIn the News – Baldness Cure from Stem Cells Within 5 Years? – Hair Loss Information – Balding Blog

Snippet from the article:

For the first time, scientists in Germany have grown hair follicles from stem cells. The feat has brought scientists a step closer to creating a cure for baldness. The study used cells taken from animals, but researchers hope to create human hair follicles from human stem cells within a year.

Stem cells are the body’s master cells. With manipulation in the lab, they can be grown into any tissue in the human body from blood to bone and even whole organs. Although stem cells are seen as the holy grail for medicine, progress has been slow and very few treatments are widely available.

However, Professor Roland Lauster at Berlin’s Technical University believes his work could be a step towards providing treatment for the 80 per cent of people who suffer from hair loss worldwide. Lauster claims the treatment – which would probably require the hair follicles to be implanted on to the head – could be available in five years.

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Read the full text — A cure for baldness ‘could be available in 5 years’

This is quite interesting and I’d love to learn more about their achievements. I’m not sure that we’re ready to say a hair loss “cure” is coming in 5 years, though. I’ll keep my fingers crossed, but as the article mentions, progress with stem cell treatments has been very slow. Anyone can guess about the timeline, but I will believe it when I see it.

(Thanks to all the readers that brought the link to my attention.)

Hair Loss InformationVegetarian, Genetics, Hair Salesmen, and Medication – Hair Loss Information – Balding Blog

  1. can vegetarian diets attribute to hair loss?
  2. and is there some sort of genetic test that will tell you if you have inherited male pattern baldness?
  3. also in Australia there are a few hair loss companies (advanced hair, ashley & martin and so on) that promote hair regrowth ect, I went to have a hair consultation with the former, but it seemed as though they just wanted a “sale” (they refused to tell me what was in there products or talk to there doctor unless I paid upfront for there program)
  4. I’ve since then saw my GP who recommended that I start taking a 1/4 tablet of 5mg finasteride to help slow the hair loss (I feel that I’m receding on the sides of my fringe). but I’m still unsure about the whole thing whether I have genetic hair loss or something that can be treated without having to take tablets all the time.
  5. is there some way I could find a hair specialist with being roped into a sales program that could give me a definite answer on my hair?!

please reply as I’m trying to loss weight to get back into modeling/acting and I feel having hair is very important to the industry

P.S I’ve heard minoxidil products such as regaine can help grow hair back or home laser therapies such a lemio is this true? and would you recommend it?

thank you

-age 24

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Vegetables

  1. A healthy vegetarian diet shouldn’t contribute to hair loss, but if you’re lacking dietary vitamins you might see some thinning.
  2. There’s a genetic test called HairDX that I believe is up to 70% accurate. But just because you have the gene doesn’t mean you’ll express the gene.
  3. There are only 2 treatments that are FDA approved for hair loss — finasteride (Propecia) and minoxidil (Rogaine/Regaine). I have no idea what the AU hair loss companies are promoting or selling, but if they don’t contain finasteride or minoxidil, they aren’t proven to treat hair loss.
  4. Your GP is right about the 1/4 Proscar tablet. That’s about the same as a Propecia tablet, but at a lower cost. I couldn’t tell you if finasteride is right for you, as I’ve not seen you and don’t have enough info. That’s a prescription medication.
  5. You can try to find a doctor in your area by using the physician search at www.ishrs.org — then use the web to research the doctor(s) a bit more.

P.S. Minoxidil can help grow hair, but finasteride actually treats the hair loss better in my experience. I’m not a fan of hair loss treatment lasers, as I’ve yet to see them work as well as claimed. I don’t recommend LLLT (hair lasers).

Good luck!

Hair Loss InformationLatisse MPB Trials? – Hair Loss Information – Balding Blog

Dr.Rassman,

I just came across Allegran starting trials with Latisse on patients with moderate MPB.. [article].

What was interesting to note was, some doctors prescribe Latisse as an off-label treatment for hairloss? What do you think of that regimen? Have you given it a try? Would it be acceptable to try that on patients who are on Finasteride and are not too bald (say NW 5)?

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LatisseI am aware of Latisse (bimatoprost), which is currently FDA approved for growing eyelashes, and I’ve seen one patient who took it upon himself to try it on the scalp with no success. The dose is quite small for eyelashes and it’s quite expensive for treating the scalp, and I’m not sure what dose would even be necessary for the scalp.

I am also aware that there’s a formal trial to find out if it works for scalp hair growth, but at this time the question of how effective it is remains. I guess we’ll have some sort of idea once they release their phase 1 results next year (which is a study of 28 patients).

Hair Loss InformationIs There a Possible Scarless Hair Transplant in Development? – Hair Loss Information – Balding Blog

Hi Doc!
Are there any unavoidable obstacles that prevent developing a hair transplant technique that is completely scarless? I am also curious about how much do you know about CIT and its look when shaved to completely bald. Another hot topic is ACell. Only a part of the donor hair follicle is needed if I’m right. Does this help to prevent scarring? And how good are the existing ACell-friendly extraction procedures?

Sorry if some of the questions are silly, and thanks for your answers!

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There is no surgery in the world that is truly scar-less. There are techniques to minimize scars, but any cut on your body will always produce a scar to some degree. Even for a traditional strip hair transplant surgery the scar is rarely seen (because it is covered by hair).

With respect to ACell, it is not a proven technology and any answer is just speculative at this point.

If ACell Works, Will It Be Standard Care? – Hair Loss Information – Balding Blog

Will ACell be more expensive than traditional hair transplant procedures?

Will it become the standard and only procedure that you offer if it is proven to work?

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ACell is too new to make any speculation at this point. Too many variables, too many questions to answer.

We made the ACell study announcement just weeks ago and I understand that people are excited (we are too), but I’m not going to make any big, speculative statements like what you’re asking of me.