Study – Microneedling with Minoxidil for Treatment of Genetic Balding – Hair Loss Information – Balding Blog

Snippet from the study:

Hundred cases of mild to moderate (III vertex or IV) androgenetic alopecia (AGA) were recruited into 2 groups. After randomization one group was offered weekly microneedling treatment with twice daily 5% minoxidil lotion (Microneedling group); other group was given only 5% minoxidil lotion. After baseline global photographs, the scalp were shaved off to ensure equal length of hair shaft in all. Hair count was done in 1 cm 2 targeted fixed area (marked with tattoo) at baseline and at end of therapy (week 12). The 3 primary efficacy parameters assessed were: Change from baseline hair count at 12 weeks, patient assessment of hair growth at 12 weeks, and investigator assessment of hair growth at 12 weeks. A blinded investigators evaluated global photographic response. The response was assessed by 7- point scale.

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Read the rest — A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia

DermarollerThere is an interesting pilot study that looked at the use of minoxidil and wounding in 100 balding men. Using a microneedling instrument (a dermal roller) and 5% minoxidil the following results were reported:

In the Microneedling group, 41 (82%) patients reported more than 50% improvement versus only 2 (4.5%) patients in the Minoxidil group. Unsatisfied patients to conventional therapy for AGA got good response with Microneedling treatment.

I was not surprised that some value for this combined treatment showed some effectiveness. I personally wonder if this is the type of service I should offer. I would appreciate your feedback.

My Identical Twin Brother’s Hair Has Thinned Less Than Mine, But I Have More Stress – Balding Blog

Hello Doctor,

I’m a 25 year old male- who has an identical twin brother. We’ve both had shoulder length hair for about 10 years.

In the past year I’ve noticed my hair around my temples and sides thinning out a lot, and noticing my scalp more after a shower. The hair on my crown has also thinned out a bit but not as bad, and the hair on the top feels much less dense and thick than the hair at my sides and back of my head, even though I have fine hair. My brother’s hair has thinned out less, but I do stress more than he does.

I finally plucked up the courage to see my doctor who gave me topical rogaine 5% and proscar 5mg to be divided into 4 (rather than propecia due to cost).
Is it safe to take the two together? And is it ok to take proscar instead of propecia?

I’d very much appreciate your advice as I’m a bit embarrassed to ask my doctor this.

We have known for years that stress accelerates the impact on balding for genetic hair loss. Your brother may eventually catch up with you, as you both age further.

It is perfectly safe to use Rogaine and finasteride at the same time, and splitting a Proscar pill into 4 pieces is equivalent to taking Propecia.




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Balding Forum - Hair Loss Discussion

I Have a Juvenile Center Hairline and Mature Corners – Hair Loss Information – Balding Blog

Dear Dr Rassman,

Probably like most males in their 20s, I’m concerned about my hairline recession. As you say, it seems as though most men will experience some form of recession in these years whether it be balding or not.

At the moment I think it is maturing only, but very unevenly. Now, I have read posts on your blog saying that one corner moving up quicker than the other is common. Well, that is indeed happening, but the middle doesn’t seem to be moving much at all.

I first noticed some recession when I was about 19/20. Up until that point, and for a fair while longer afterwards, my hairline was extremely low and straight and so fortunately caused me no concern at all. When I first observed some change at that age, it wasn’t so much recession as that the corners were a little less dense. The left side was also less dense than the right.

I remember at that time I had experienced some diffuse shedding (telogen effluvium) and was worried I was balding. I consulted a hair specialist who didn’t seem to be aware of the ‘mature hairline’ concept and said that any recession is balding, but said I didn’t appear to be balding.

Since then I’ve been keeping a close eye on my hairline. I’d say only in the past 6 months (and I’m 23 now) has there been more marked change. The left side seems to be thinning out more completely to establish what I think (or hope) is its NW2 mature shape. I’d say the recession will be about 1.3inch from the corners. However, the middle part is still basically juvenile. The right is perhaps a NW1.5 and still more dense than the left. Is this normal?

The problem is, the angle created by a ‘juvenile’ center and a mature corner makes it look weird, more like balding, even though I think the corners are still within mature parameters. Can I reasonably expect the middle to move up by a couple of centimeters to form a less sharp, more straight and rounded angle? The problem is, it seems as though a lot of men bald by receding up through the corners, while maintaining the middle. It’s possible this may be caused by styling, i.e. the left is maturing more rapidly as I tend to comb/style from that side (using products/dryers) so perhaps the miniaturizing hairs are falling out quicker.

There is balding in my family, as both my older brothers started balding early (but at different rates), and my father also started balding in his late 30s/early 40s. However I seem to have escaped the late teens balding pattern (which struck my brothers, and they never had a really strong teenage hairline like me), and my father actually seemed to maintain a juvenile/NW1.5 hairline and his balding pattern came mainly at the crown, not the corners. My progression thus far does not seem to fit any of these patterns.

Is this encouraging? Or is it simply a matter of not being able to tell if you’re balding until you actually ARE? My grandfather on my father’s side never lost his hair and had a full head of hair when he passed away in his 80s, and my uncle on that side also never experienced MPB (though appears to possibly be experiencing some thinning at 60, but at that age I’d say he doesn’t have standard MPB).

I think my father on my mother’s side experienced balding in the 40s, but I don’t know much about my family on that side.

To summarize, it’d be a lot easier if hairlines stayed put! For sure, a solid juvenile hairline can look odd on a grown man, but NW1.5 seems the perfect compromise. Any comments on this would be greatly appreciated !

Thank you

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The central part of the hairline has a different genetic code in many people. When it is small, I call it a persistent forelock, but when it is large, it takes on a different appearance, though it still has the genetic code of a persistent forelock. What you are describing is such a phenomenon. The corners mature, while the central portion of the hairline remains at the juvenile level. I just wrote an article on this topic for publication in the Journal of Facial Plastic Surgery, which is due out sometime this month.

What I think you should do is determine if you have balding on the top and/or crown of your head by getting a hair bulk analysis with the HairCheck instrument I have discussed previously on this site (see here). I suspect that your corners will continue to rise, at least, until the mature hairline areas are reached — assuming you do not have genetic balding.

Should I Take Finasteride Early in the Morning When Testosterone Is Highest? – Hair Loss Information – Balding Blog

Hi Doctor Rassman,

Thanks for all your great work you do answering people on here. Just wondering about what time I should take finasteride, and if my current regime could make it less effective? I have been taking finasteride for about a month and a half, so it’s obviously too early to tell if it’s working, but I have had no discernable side effects. I work evenings, so because of my routine I wake up around midday, and take the quartered 5mg then. I have heard that it’s best to take it very early in the am. Is testosterone highest in men generally in the early morning, or is that just because it’s when the average man wakes up? Should I wake up at 7 to take the pill then go back asleep?

Hope to hear your answer,

Thanks again

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There’s no need to wake up early just to take finasteride.

I used to tell patients to take it when they woke up, but that was really just because it would help them to remember to take it as part of their morning routine. Really though, there is no evidence that finasteride in the morning or the evening is better one way or the other, as long as you remember to take it regularly each day.

I Saw Immediate Rash and Shedding After Starting Rogaine – Hair Loss Information – Balding Blog

Hi,
I am a 45 yr old female and have been diagnosed with hereditary loss. I started rogaine 5% about 10 days ago, I immediately developed a rash and started to shed more than 200 hairs a day and worse when I washed it? My hair was already diffused on top and now it is ten times worse.

I want to stop use because i cannot afford to continue to shed like this. Will the hair I lost grow back without use of rogaine, or is it gone forever?

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There is no way to predict if the hair will grow back, but I suspect it will once the allergic reaction passes. It will take months to see the positive impact on regrowth.

I Currently Have No Signs of Hair Loss, But Will I Go Bald at Some Point? – Hair Loss Information – Balding Blog

Hi,

I am a man in my mid 30s and currently have no signs of hair loss. Recently however, I have developed a fear of going bald. My Dad has a full head of hair at 60 and his Dad had a full head of hair til his death at 61. However, my Mother’s Dad went bald from his early 40s and my Dad’s brother started going bald in his early 30s. I need to know – will I go bald?

Look for any advice you can give. Thank you!

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I have no way to know if you will go bald. I also have no way to know if you will develop heart disease, or if you will get audited by the IRS. Determining who will go bald is not as simple as just looking at the age of when your father, grandfather, or uncle went bald. Hair loss can skip generations.

You can find out if you have any signs of balding by having your hair bulk analyzed. Since you’re in your mid-30s, if the test does not show balding, then you are probably in the ~90% probability of not developing balding. For most men that have genetic hair loss, the balding process starts in their 20s.

At this point though, there is really no way for me to tell you for sure if you will go bald, if you will start thinning, or if you will have no loss at all.

Hair Loss InformationAfter I Read About Propecia Side Effects, I Had Them the Next Day! – Hair Loss Information – Balding Blog

I am a 26 year old man with male pattern baldness. I have had had three 1 mg doses of Propecia over three days – normal course. After the second day, I was able to get a normal erection pretty easily. On the third day, I came home terrified I wouldn’t have an erection, as I had been reading so much about potential side effects, and on the fourth day I seem unable to get one.

I have never had this kind of issue before. It might be psychosomatic or real. Should I see it through for a few more weeks or days, cut dosage, stop, etc.?

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Some men are highly suggestible, so I would not be surprised if you talked yourself into the problem. The power of suggestion is a very real thing. Reading and worrying about the side effects could’ve given you anxiety, which in turn could cause the same problem you’re describing.

I am not your doctor, but you should make it a point get his/her advice. Propecia is a prescription medication, so before you cut the dosage or stop the medication, talk to the person that prescribed it to you.