Month: January 2023

In early 2011 I had a rare adrenal tumor removed called a pheochromocytoma. Doctors also removed the affected adrenal gland the tumor was attached to. This type of tumor spontaneously, without provocation, releases epinephrine, norepinephrine and dopamine. Chemicals collectively referred to as catecholamines. These are your fight or flight chemicals and when the tumor releases them you feel very “wound up”. After the tumor was removed, my catecholamine levels went back to normal and I again felt normal.

In late 2011 I started Propecia. I started on .5 milligrams per day and later reduced that dose to .5 milligrams 3x per week, which I am currently taking. A dose much lower than the standard dose of 1 milligram per day. Almost immediately after starting Propecia, I began to feel like I did when I had the tumor. Spontaneously “wound up” even in the absence of external stimulus.

Recent testing reveals my catecholamine blood levels are back up and my oncologist suspects another tumor. Appropriate scans for tumor detection are occurring “as we speak”.

Are you aware of any evidence that Propecia can cause elevated levels of epinephrine, norepinephrine or dopamine? I have read numerous claims that Propecia can cause anxiety. If this is true, could this anxiety then trigger a “chemical cascade” in which catecholamines are released at high levels.

Thank you for your expertise in this matter.

I know I must sound like a broken record, but you really need to discuss personal medical issues with your doctor.

I wouldn’t expect Propecia to have anything to do with dopamine or other catecholamines. Propecia is a 5 alpha reductase inhibitor, which works to diminish the conversion of testosterone to dihydrotestosterone (DHT).

In my experience, the anxiety caused by Propecia are in those men who read too much about Propecia’s side effects on the Internet without discussing the issues with their doctor. Then again, anxiety could indeed be a rare symptom associated with Propecia, but it’s something that needs further study. The studies that I’ve seen which link Propecia to anxiety or depression were based on interviews with men from a Propecia complaint forum, and the bias is something I’ve discussed before.

Doctor,

Have you ever heard of Propecia causing TE?

No, I have not.

Can propecia cause platelets in the blood to lower. My platelet count was 125 and my doctor said its not anything to worry about. I know the normal range is 150-450.

please help doctor

I would listen to your doctor. I do not believe Propecia has anything to do with low platelet counts, but I did find a case report from 2002 in the medical literature that mentioned it. I haven’t seen more cases mentioned in the 12 years following the report, so I’d expect if finasteride does cause low platelet counts, then it is very rare.

Hi,

I must be at an early norwood 3, in my mid 20’s and have started propecia, (its been a little over a month), has two questions;

1) Have there ever been cases where a complete reversal of baldness has taken place with use of propecia ALONE.

2) Could you explain the post finasteride syndrome (extremely scared of reports on the internet) and was wondering how often it is seen in patients (not just the sexual side effects, but also all the others described by some patients such as brain fog, memory loss, stumbling on words etc etc)

I have done a lot of reading and decided to take the pill anyways, so far no known side effects, except for a slight pressure in my prostate which went away within a week.

I have seen some dramatic results with Propecia, but I would not say a complete reversal.

I do not know the exact issues that are referred to as this post-finasteride syndrome. I realize there are anecdotal stories from people on the Internet who claim Propecia ruined their lives forever, but in the 15 or so years that I’ve been prescribing this medication, I have not seen anyone with permanent and lasting effects after they stop taking it.

I have read about it online, I know a select few readers/commenters on this blog are very vocal about it, and we’ve written about the interviews with patients that have resulted in a study that the media went crazy over… yet I still don’t know what is considered “post-finasteride syndrome”, since there are so many random side effects that people apply to this medication.

I do not know how Propecia may cause pressure on the prostate. I do not think I would even how that may feel. Please speak with your doctor on these issues.

Some reports shown that propecia is not suitable for women as it may cause birth defects.Therefore, I want to know if a man is taking propecia continuosly, then will the contents of the propecia transmitted to women during having sex with his partner(which is transmitted via kissing or sperm) and indirectly will it affect women’s health?

thanks for your reply. I do appreciate it.

From a practical perspective Propecia is NOT carried via sperm/ejaculate, when kissing, or having intercourse or oral sex.