As hairs grow longer, they lose their thickness

The first picture is from Dr. Robert Haber’s magnified study of a hair scan of a single hair on one of Dr. Paul Cotterill’s female patients. It revealed that hair thickness and shape changes as the hair grows longer. The measurement scan below demonstrates the changes in this 21 cm long female single hair. Telogen is on the left (the end of the hair cycle) and the start of anagen on the right (where the new hair started to grow out from the scalp) showing how the shaft thickness and bulk builds as the hair starts growing and is widest at about 14-15 cm (about 15 months into the growth of the hair). It is clear that the hair thickness is greatest at the 14 -15 cm. length of the hair in this female patient. Dr. Haber told me that this was a normal female hair and she had no symptoms of a hair disorder. Clearly we need to understand the various conditions that this technology is capable of showing us as hairs are evaluated with regard to many different treatments.

In the second chart, a hair shaft thickness is shown over its length and the researchers, Dr. Michael Rabin and Dr. Robert Haber show the impact of an event that occurred in this particular patient’s hair (which had grown out for 22 months) but the event occurred 16 months into its growth cycle. The large arrow shows pointing down shows the timing of the event and it this case it was a PRP treatment 6 months ‘in time’ prior to the hair being cut off at its base at 22 months growth. Note this hair’s emergence from the scalp (beginning of anagen on the right) and the point where PRP was administered 16 months into its growth cycle (shown with large red arrow pointing down). It is easy to see the point where the event occurred, but interpreting it is another story. Is this a good result or a bad one? Was the hair ‘healthier’ after the PRP injection. The graph suggests it was less thick, but maybe it was a healthier hair?

This is exciting research to me because now after seeing it, I would want to know the impact of drugs like minoxidil on a normal terminal hair, (we now believe that there is no impact), the impact of finasteride on a miniaturizing hair (we now believe it increases the hair shaft thickness) and the growth of a single long hair with the patient on finasteride over time (does the benefit build slowly or is it a one time hit?). I just loved the creativity of these clinical researchers in producing a tool that can expand our knowledge in what is still, at times, a ‘Black Art’ for, the treatment of hair loss. . (Ref: http://neoangels.net/ishrsboston/hairscan.pdf)


2020-01-03 10:19:37As hairs grow longer, they lose their thickness

Artificial Hair

I understand that there is something out there called artificial hair. Where can I get it and how does it work?

Artificial hair is a product sold in Asia and limited countries in the western world. It has been banned by most countries because it must be surgically implanted with a special sewing needle. This would be a procedure that would need FDA approval and it has not been approved as safe in the United States. Many patients’ bodies will actually reject the artifical hair as it would any foreign body once it is implanted into the scalp. I have seen some patients with wonderful results. It gives ‘instant hair’ and as a result it is a big selling point in countries where it is allowed, BUT I have also seen patients that have developed massive scalp infections from these ‘artificial hairs’. There is a trade off and safety is sacrificed in exchange for short term benefits. Biofibre is one of the sites for artificial hair. Reading it might give you more information, but I would strongly caution your pursuit of this as a solution for your hair loss.

Artificial hair does not need to be included in any hair cut and you can not grow your hair out with them as you could with hair transplants. Hair transplants allow you to grow your own, natural hair for as long as you live.

Artificial Hair Implanted with Lasers?

Dear Doctor.

I lost 50% of my hair and I found in Lebanon a place called Advanced Hair Studio Center. They make fiber hair and stick it by using Laser. As I know before this is banned in Europe, did you have any advice for me to do it? If yes please advise me if 3000 pcs is enough to cover 40 square centimeter?

If the fibers are being put into the skin, you will almost certainly run into rejection and infection issues. Artificial hair is dangerous and banned in most countries.


2006-07-31 08:51:51Artificial Hair Implanted with Lasers?

Article showing finasteride in scalp

This is an interesting article showing the effects of varying doses on DHT when finasteride is taken at varying doses.

https://pubmed.ncbi.nlm.nih.gov/10495374/


2020-04-25 13:36:28Article showing finasteride in scalp

Article on Topical Finasteride worth reading (2015 date)

Effects of a novel finasteride 0.25% topical solution on scalp and serum dihydrotestosterone in healthy men with androgenetic alopecia

December 2015, International journal of clinical pharmacology and therapeutics 54(1), DOI: , 10.5414/CP202467, Maurizio Caserini, Milko Radicioni, Chiara Leuratti, Renata Palmieri

Objective: The effects on scalp and serum dihydrotestosterone (DHT) of different doses of a novel topical solution of 0.25% finasteride (P-3074), a type 2 5?-reductase, were investigated in men with androgenetic alopecia. Methods: Two randomized, parallel-group studies were conducted. Study I: 18 men received 1 mL (2.275 mg) P-3074, applied to the scalp once a day (o.d.) or twice a day (b.i.d), or 1 mg oral tablet o.d. for 1 week. Study II: 32 men received P-3074 at the dose of 100 (0.2275 mg), 200 (0.455 mg), 300 (0.6285 mg), or 400 (0.91 mg) ?L or the vehicle o.d. for 1 week. Scalp and serum DHT and serum testosterone were evaluated at baseline and treatment end. Results: Change from baseline in scalp DHT was -70% for P-3074 o.d. and approx. -50% for P-3074 b.i.d. and the tablet. Serum DHT decreased by 60 – 70%. The doses of 100 and 200 ?L P-3074 resulted in a -47/-52% scalp DHT reduction, similar to the 300 and 400 ?L doses (i.e., -37/-54%). A -5.6% inhibition was observed for the vehicle. Serum DHT was reduced by only -24/-26% with 100 and 200 ?L P-3074 and by -44/-48% with 300 and 400 ?L P-3074. No relevant changes occurred for serum testosterone. Conclusions: The novel finasteride 0.25% solution applied o.d. at the doses of 100 and 200 ?L results in an appropriate inhibition of scalp DHT potentially minimizing the untoward sexual side-effects linked to a systemic DHT reduction.


2020-03-23 16:32:28Article on Topical Finasteride worth reading (2015 date)