i was wondering, i notice finasteride and dutasteride are metabolized in the liver by a bit different processes, i know they say dutasteride (type 1/2 in) since inhibits both may have more side effects, but i was wondering (as far as liver-wise) would dutasteride be less of a burden on the liver since only .5mg compared to fin 1mg, and any recent info as to type 1 AR role in hair loss if any?
The term burden is not correctly used. When a person has known liver disease, the rate at which the liver metabolizes drugs (and other metabolites) is slower. That means that the drug level may be higher in people with active liver disease when taking a standard dose. This can be managed with dose reduction so that the proper blood levels are maintained. Knowing that there is liver disease should direct the doctor to check blood levels of the drugs that are metabolized by the liver.