Hi Doc,
I have asked you several questions in the past, all of which you have given me very good responses, I am very grateful for that.
This is just a speculative question; If 100% of DHT was to be blocked do you believe the number of patients growing hair would drastically improved.
Blocking 100% of DHT is seen in those individuals who are born with 5 alpha-reductase deficiency and there is no balding in these men. Androgenic alopecia (AGA), otherwise known as male pattern baldness (MPB), is genetic… and genetic predisposition will always win with any DHT production.
Castration is a radical way to block DHT formation by removing the major testosterone influence and we know that there is some androgen hormone production from other than the testicles (we do see women with androgenic influences on their genetic hair loss in some situations). I suspect, however, that a 100% block of DHT would stop the hair loss at whatever stage it is in, but not reverse what had already happened.
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