Reader Doesn’t Think ACell Will Work – Hair Loss Information – Balding Blog

I don’t believe that A-Cell will work. Is there actually any proper evidence of this technology working anywhere? It seems to be just that guy with the finger which I am unsure whether has been exagerrated/fabricated. Other than this it feels like all hype.

Also, it seems like when you pluck these hairs, you have to take out so much of the hair that logically thinking I’m not even sure if they will grow back the same thickness (if at all). Now I know people will come back with how they wax their legs, chest, arms or even their head regularly and they always grow back, but I seriously doubt that when a normal person plucks/waxes, they are extracting the amount of tissue required to perform the A-Cell procedure.

In addition, Jerry Cooley states in his presentation on one slide: “you can see the thicker FUE grafts vs the thinner plucked hairs” – so this really isn’t what it is being hyped up to be?

This unfortunately to me feels like just another method of doing a standard hair transplant. Maybe it will infact become the common way as it appears to allow it to be done without any scaring at all, but right now it looks like you would actually be worse off using A-Cell method over current methods, as the hairs at the donor and recipient region will grow back thinner, that is if they grow back at all.

I don’t know of Dr Cooley’s reputation, but from watching his presentation this just doesn’t seem that impressive. The only way it might work is using beard hair that thinned out during the process and ended up like scalp hair, but even then if this worked perfectly is it really a cure? You can’t do whole units and can you control the direction?

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Perhaps you are right, but in the spirit of scientific research we have to try. That is one reason why we are trying to conduct formal IRB approved clinical research. It will either prove or disprove the concept.

The hope is that the plucking approach will yield more hair than moving the hairs around with traditional transplantation. The fact is that not only us (NHI), but the entire hair transplant surgeon community needs to be able to replicate this technique to stand up to the test.

Hair Loss InformationPhytolium 4 – Hair Loss Information – Balding Blog

Hi Dr,

I read your blog everyday. It’s great. My question is simple: have you ever heard of a new treatment called Phytolium 4? [Press release here]

I’ve just seen a billboard ad in a bus stop and I guess it is being launched on a few countries (not sure if they’re already in the USA, I live abroad). They claim some numbers but I can’t find any real reviews online, so I guess we have to wait a couple of months to confirm the hype (if any).

I just wanted to check what is your opinion/expectations about this product. Thank you very much

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Phytolium 4I like to see what are called double blind studies and other controlled research that would prove value beyond a shadow of a doubt. The problem here is that there is no proof that I would define as objective, just claims that the product works.

This Phytolium stuff is a French-made, plant-based shampoo and lotion treatment, but regardless of the ingredients, they are marketing it as an alternative to the only two proven medications that grow hair (minoxidil and finasteride). And just like hundreds of other products, they claim no side effects and great results with this Phytolium 4.

The same maker of this product sells Phytocyane, which we wrote about here. I would love to believe these products work as promised, but I would need to see more proof than a slick website and the seller’s word. Please feel free to try it and report back, though.

Do People Get Hairline Transplants Knowing Hair Loss Could Progress? – Hair Loss Information – Balding Blog

Dr. Rassman,

My frontal hairline has been thinning for sometime now and I was doing a bit of research on the internet on frontal hair restoration. And I see a lot of people go through this procedure. Do most people go with this procedure knowing/assuming their frontal hairloss/receding has stabilized or do they stay fully committed to getting more if their hairline recedes further?

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Many of my patients have hairline transplants. Actually, the great majority of my patients that have hair transplants have hairline changes! I always caution the young men (under 25 years old) that many hairline changes occur with maturation of the hairline, which is often mistaken for early hair loss.

The most important thing we need to determine (a very important discussion between the patient and doctor) is how far the existing (non transplanted) hairline may recede in the future. We must plan for this and the patient must understand its consequence of possibly needing further surgery. This is what we refer to the Master Plan.

Readers Respond to Suicidal 18 Year Old – Hair Loss Information – Balding Blog

We received a lot of emails about last week’s post — I’m Suicidal Over Losing My Hair at 18 Years Old! — and I wanted to share this one with the rest of the community.

Dr. Rassman,

I read this blog regularly and when I read your post yesterday about a young man dealing with suicidal thoughts, I had to write in.

Young people out there need to understand that they have options but doing something drastic (like a transplant at 18) years old or worse (harming yourself) only eliminates options. I came to your office last year young, scared and anxious about hair loss myself. I was convinced that things were only going to get worse, but a year ago there wasn’t a hair bulk analyzer or A Cell. Imagine, just a year later and suddenly I am hearing about all these innovations. Maybe I overreacted?

It is amazing what happens when you take a deep breathe, research your options and gain a little perspective. I was given great advice by the doctors at NHI and they were words I needed to hear. Hair loss still bugs me but I now have every option open to me because I did not jump into a rash decision and young guys (I am 25 and empathize with you) need to understand that, just because you are not happy with what the mirror is showing, it doesn’t mean you can’t be happy ever again.

This is not the end of the world. Balding doesn’t rob you of your vision, your hearing or your overall health. This young man still has eyes to see the world, ears to listen to wonderful music and a capable body that can laugh, love and live. Getting a quality doctor to help you deal with your problem will keep you from being a slave to your hair and will help you get on with living.

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While most of the emails (and comments) had positive messages of support, I felt the above email perfectly expresses what many compassionate people relate to. Thank you for writing.

Could ACell Regrow Hair on Its Own as a Topical? – Hair Loss Information – Balding Blog

Hi there, I apologise if this is a silly question, it’s regarding the acell research that is under way at the moment: if the drug has the potential to regenerate cells including hair follicles – would it not be possible to use this drug in a preventative way by applying it to thinning areas affected by DHT in much the same as minoxidil?

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The concept with the ACell is that it will stimulate the stem cells that are present in the plucked hairs to produce another mature hair from the plucked hairs. As the original hair will regrow, you get 2 hairs from one if there is a 100% growth of the plucked hair. That’s the idea, anyway. It isn’t a DHT blocker.

If ACell Could Possibly Give You Unlimited Donor Hair, How Isn’t It a Cure? – Hair Loss Information – Balding Blog

I have a few questions about ACell…first of I know it’s in early stages and a lot needs to be done but it it works I want to know this…

  1. From my understanding it will involve plucking hairs from the donor hair putting into the top and then wait a few months for new hairs to sprout from the plucked areas to keep transplanting?
  2. If that is the case how is not a cure where you once said somewhere? If plucking out hairs and they keep regrowing won’t you have an unlimited donor supply!?

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Yes, the hair is plucked from a donor area and placed in a bald area. It is not a cure, because you are still genetically bald. You just added hair to look non-bald. If that was the definition of cure, then Propecia and hair transplant surgery could be considered a cure. If you are referring to the “theoretical” unlimited donor hair supply as a cure, then I suppose that would fit. But theory and practicality (of multiple surgeries) does not always work out in the real world.

There are a lot of unanswered questions here. I do not have all the answers, and the proliferation of information on the Internet makes it difficult to keep ahead. In other words, we are BEGINNING our clinical study. We can all speculate what the study will show, but as far as we are concerned, it is all hopes and dreams at this point. We promise we will keep you all up to date.

Donor Area – Hair Loss Information – Balding Blog

I have a question about the donor area scar. It seems like most donor area scars begin over the ear and proceed to the back of the head. Wouldn’t it be better to remove the donor hair from the nape of the neck where the skin is more elastic and the scar would be less noticable? Is this a viable option? Thank you

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Your theory may be valid, but the hair on the nape of the neck is not considered permanent hair. Let’s assume that hypothetically the hair at the nape turns out to be permanent — you’d still run into the problem of scar visibility. A wound scars readily at that location. Many men like to keep their hair short and faded (cut short) at the nape of the neck, so having a scar there would really be a problem for them.

Finally, most donor area scars do not begin over the ear (at least not my patients).

Overplucking Eyebrows – Hair Loss Information – Balding Blog

Hello doctor. I was wondering how long eyebrow hair takes to regrow from overplucking? I know that in some cases it may never grow back, but I have read that the time frame in some cases can be from a few months to a couple of years. So, can a follicle possibly still regrow hair years later? Thanks for your insight.

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I would say it takes a few weeks to months for eyebrows to grow back after plucking. If you haven’t seen growth after a year, I would think your chances for regrowth are very low, though anything is possible. Continuous plucking is the most common cause of hair loss from the eyebrow.

Finasteride, FDA, and Prostate Cancer Prevention – Hair Loss Information – Balding Blog

One of my favorite BaldingBlog contributors (who shall remain nameless) sent in some great insights about FDA advisory committees. We’ve previously posted his thoughts on the LaserComb, clinical trials, and FDA trials. This post will be used in the future as a point of reference:

    Dr Rassman,
    Given the many questions related to consideration of FDA expansion of the finasteride label for prevention of prostate cancer, your readers may wish to access the data themselves and better understand the process (which becomes more transparent and less “conspiratorial”).

     
    The recent finasteride and dutasteride opinions noted in the Dec 3 Balding Blog posting are not from the FDA, but are from an independent group termed the Oncologic Drugs Advisory Committee. The committee is composed of 18 voting members (and several non-voting members) – mainly oncologists, with some statisticians, epidemiologists, and a patient representative, the former mainly from academic institutions.

    The FDA eventually considers the committees opinion in approval or withdrawal of drugs (or “expansion” of a drug label for a new indication). The FDA usually follows the recommendations of advisory committees, as the committees’ recommendations are presumably “data-driven” and the FDA typically comes to similar conclusions. However, as in the case of many decisions that are split or where significant differences in interpretation of risk-benefit exist, the FDA has occasionally approved or rejected a drug against the recommendation of an advisory panel. Examples of split Advisory decisions (where a majority vote did occur) are the opinions this year related to several weight loss drugs.

    The Oncologic Drugs Advisory Committee voted 17-0 against expanding the label for finasteride to include prevention of prostate cancer. A unanimous vote by FDA Advisory Committees is rare. I have no special knowledge of the meeting. This decision was based in part on data from the 19,000 patient Prostate Cancer Prevention Trial and the belief that the data did not support the risk benefit profile (i.e. possibility of increased aggressiveness of tumor did not outweigh reduced risk of low-grade tumors). As with all such committee meetings, which are open to the public (including listening via live webcasts), the transcript will be published and available within a few weeks at the FDA’s web site.

    However, interested readers can go to the FDA web site now and access the Briefing Document and presentations given to Committee members from the drug company seeking approval. This information is public and typically posted several days before the meeting. The meeting was held on Dec 1, but the date of posting was Nov 26 (see under Oncologic Drugs Advisory Committee). The info can be found at the following links [note – all are PDF files]:

  1. Draft Agenda for the December 1, 2010 Meeting of the Oncologic Drugs Advisory Committee
  2. Briefing Information for the December 1, 2010 Meeting of the Oncologic Drugs Advisory Committee
  3. Draft Questions for the November 30, 2010 Meeting of the Pediatric Oncology Subcommittee of the Oncologic Drugs Advisory Committee
  4. Merck Briefing Information for the December 01, 2010 Meeting of the Oncologic Drugs Advisory Committee
  5. FDA Briefing Information for the December 01, 2010 Meeting of the Oncologic Drugs Advisory Committee
  6. GlaxoSmithKline Briefing Information for the December 01, 2010 Meeting of the Oncologic Drugs Advisory Committee
  7. Draft Questions for the December 1, 2010 Meeting of the Oncologic Drugs Advisory Committee
  8. Draft Meeting Roster for the December 1, 2010 Meeting of the Oncologic Drugs Advisory Committee
  9. Webcast Information for the December 1, 2010 Meeting of the Oncologic Drugs Advisory Committee

Reader Tells Others to Calm Down Over ACell Inquiries – Hair Loss Information – Balding Blog

Hey Dr Rassman i hope your day is treating you well.

Being a hairloss sufferer myself i can relate to the extraordinary anticipation and hype surrounding the new buzz word in the field of hair restoration ”Acell”. However i also realize that this is far from establishing itself as a practical solution to genetic alopecia(if it even makes it that far). As a hair restoration physician i imagine you grow tired of those ”cure” type perennial questions. In my opinion readers need to recognize that when the hairloss community is equip with innovators like yourself Dr Rassman it provides us with the best chance possible of making the most out of these types (Acell) situations.

Being a daily reader of this blog i have nothing but good things to say about it. There is not a doubt in my mind that Dr Rassman and the other physicians that contribute to the blog will be efficient at posting occasional updates. So for a lack of a better term just ”chill out” time will tell…..

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ChillThank you for your support! I don’t mind the large amount of emails I’ve received with ACell questions, as I kind of expected that… but I don’t want to give anyone the wrong idea about what it can do (we’re still trying to figure it all out).

We will most definitely update the readers of this site on our progress as we can.