Hair Loss InformationIs Finasteride Really That Much Different than Saw Palmetto? – Hair Loss Information – Balding Blog

Hello. I have been balding for around 4 years (started when i was 17 unfortunately) and I have searched for solutions for my hair loss endlessly to no reward. I have used multiple shampoos, different types of minoxidil (spectra-DNC and more recently rogaine foam- had to stop rogaine foam because it seemed as if i was shedding ridiculous amounts for way to long ~1 month) and still nothing.

I feel like have no where else to go besides into the realm of anti-hormone therapy. By that I mean finasteride (propecia) or Saw Palmetto pills. My question now is, is the herbal route (saw palmetto) that much different than the pharmaceutical route (finasteride)? They both inhibit 5-alpha reductase leading to lower levels of DHT so what makes one drug better than the other?

Another question I had was, after testosterone is inhibited from becoming DHT, what happens with the extra testosterone? Does aromatase convert it to estrogen (-> leading to gynecomastia)? Does it have the same effect as steroids whereby exogenous testosterone leads to smaller testicles and decreased sperm count?

Thank you.

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For starters, peer-reviewed clinical studies about saw palmetto as a DHT blocker do not exist, making it difficult to make any comparison. It’s a catch 22, I know — it’s a natural herb so it won’t be able to have any patent protection, thus no company will put up the funding to get a good study done. Still, Propecia (finasteride) does have such studies, meaning there is real data to look at and make judgments on. If you don’t want to go the pharma route and would rather go with saw palmetto, that is entirely up to you. I don’t think the results will be there with saw palmetto, however.

Much of what you state has bits of truth to it, but it’s not a complete picture nor is it really helping you understand things. Hormonal pathways are very complicated and you cannot narrow things down to explain things to suit your needs. I am not going to explain all the biochemical pathway of testosterone to DHT to aromatase, etc. It’s a bit too abstract for this site, and honestly I don’t want to teach a course in college biochemistry.

So lets start from the beginning… and by that I mean, what are your goals? If your goal is to find a cure for hair loss, then you will not find it. There is no cure for hair loss. If your goal is to slow down male pattern hair loss then the only thing that I know of that really works is finasteride and topical minoxidil. These medications do not stop hair loss per se, but will help slow down the loss before your genetic predisposition eventually wins over (this could be many years). Everyone responds to the medication differently, and ALL medication have side effects.

Propecia’s side effects have be beaten to death on various web forums, much of it being false or blown out of proportion. Take note, Propecia is not the only medication that has side effects. Just look up any common medication on the Internet and I am sure you will find loads of false (as well as true) information and their horror stories. My guess is that Propecia is a sensitive topic to most, because words such as “erectile dysfunction” and “decreased libido” are key issues for any male patient. If you look up medications like Prozac or drugs used to treat high blood pressure, you will also find “erectile dysfunction” as one of the many side effects.

The patients who are considering Propecia should be aware that side effects exist, but in reality (from my personal medical practice with actual patients I see at my office) the incidence of “erectile dysfunction” is as stated in the medical literature — 1 to 2%. Those patients with these issues can stop the medication and the side effects reverse within a week. The incidence of gynecomastia is about 1 in 300 to 1 in 500 (I am not sure of the exact published number), but I only remember one patient reporting sensitive breasts about 3 years ago. He stopped the medication and he was fine afterward.

One last thing I wanted to point out — Propecia does not give you small testicles or decreased sperm count.

Hair Loss InformationIn the News – Bald Chimp Looks Human, Still Throws Feces – Hair Loss Information – Balding Blog

Snippet from the article:

GuruOther males may worry that losing their hair will make them less appealing. But for Guru the chimpanzee, his baldness has turned him into a star attraction. The 20-year-old, who is suffering from alopecia, has lost the hair from all over his body.

But the mischievous chimp still brings hundreds of visitors flocking to Mysore Zoo in southern India – despite greeting them by throwing stones. Dr Suresh Kumar, a zoo vet, said: ‘Everybody wants to see his biceps and triceps.

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Read the full story (with many more photos) at DailyMail UK – Guru the chimp suffering from alopecia looks human

This is the 2nd bald chimp in the news this month. You may recall we mentioned Jambo the chimpanzee from the UK with alopecia… and now here’s Guru from India!

The article points out that Guru still gets down to business by throwing his poo at visitors to the zoo, so at least his alopecia hasn’t left him feeling depressed.

Dr Christiano’s Alopecia Areata Discovery, Revisited – Hair Loss Information – Balding Blog

I´ve found this article on the internet about alopecia areata. Can you please share your opinion about this.

Physorg.com – Professor discovers genetic basis for hair loss

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I think this is the same news that was announced in July. I’m not sure why Physorg.com is just getting to it now, though the article you linked to appears to have a little more info than the previously announced news… and a new video interview with Dr. Christiano.

At any rate, the discovery is great news and hopefully will lead to new treatments for alopecia areata in the future.

Hair Loss InformationWill Propecia Make My Beard Not Develop? – Hair Loss Information – Balding Blog

I have read on various web-sites that beard growth is stimulated by DHT. I am 20 years old and have yet to develop a full beard. I take propecia for male pattern baldness, is this likely to have a noticeable effect on the development of my facial hair or stop it completely?

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Probably not, but the human physiology is not so simple. Beard development (or non-development) is not a typical side effect of Propecia (finasteride). If you don’t grow a beard for some reason, the most likely culprit is your genetic trait and not the drug.

Live from ISHRS 2010 Meeting in Boston – ACell Discussion – Hair Loss Information – Balding Blog

Hi Doctor,

I am assuming you’re attending the ISHRS meeting and was hoping you could attend the ACell discussion to report your opinion on your blog. Here’s the press release that caught my eye: MatriStem in Hair Restoration at Annual Scientific Meeting

Thanks

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ISHRS 2010I’m actually in Boston at the International Society for Hair Restoration (ISHRS) Scientific Meeting, and wrote this on my little netbook to get you a timely response.

The ACell material is reportedly derived from Porcine urinary bladder. Here’s a good, short description of ACell’s product from another conference they attended: “MatriStem® devices are a naturally occurring, completely resorbable, acellular, extracellular matrix. Different collagens, bioactive components and intact basement membrane help surgical sites remodel by supporting the growth of new blood vessels, connective tissue and muscle.

At the ISHRS meeting, two doctors presented its use in plucked hairs. Hairs were plucked out of the beard or side hair and amongst these hairs the best ones were identified. The ACell was applied to the plucked hairs and then placed into recipient sites. Some of these hairs grew (less than 50%), but the good news is that supposedly the site where the hair was plucked also grew out a hair. The data is very sketchy and there is clearly no well identified process — no right way or wrong way to do this. But in theory, new hairs come from the process. If what was presented is accurate, then the dream of something for nothing (hairs that are essentially replicated) produces more hair than what was there prior to the procedure.

This MicroMatrix has experience of use in keloids, other types of wounds, and in the treatment of lacerations, ulcers of the skin (diabetic and vascular in origin), and burns. From what was presented, a great deal of interest was generated, but there is much research that needs to be done before it can or should be offered to the public. I suspect that the research will be on the fast track as many doctors saw the opportunity to make more hairs than they started with.

Coconut Oil Head Massage – Hair Loss Information – Balding Blog

What are the benefits and drawbacks of head massage with oil? Some people get a vigorous head massage using olive/coconut oil. Whats your opinion?

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CoconutMy opinion is that a head/scalp massage feels nice, and I quite enjoy the smell of coconut oil. Aside from relaxation and perhaps stress relief, massages with coconut or olive oil do not have any association with hair loss (if that is what you were asking). I’ve also read that the oils can help if you have a dry scalp, but I’ve never used them for that.

There are lots of claims about scalp massage being a way to treat hair loss due to helping with blood flow throughout the scalp, but blood flow issues aren’t usually the cause of hair loss. Genetics are the reason for the great majority of hair loss cases, not poor circulation.

What Could Cause Eyebrow Thinning? – Hair Loss Information – Balding Blog

Hello,

I’ve been suffering from eyebrow hair loss for a while now. It started last year summer time when I started noticing my eyebrow losing hairs starting from the outer edge. As time progressed, both my eyebrows lost hair to the point where I only have 3/4 of both my eyebrows. Eventually, I started losing eyebrow hair from the inner area. Currently my right eyebrow isn’t as bad but my left eyebrow is noticeably changed a lot. It looks like as if I only have a patch of hair left, near the inner eyebrow area. I understand that it will be difficult to diagnose without meeting you but what do you think is causing my eyebrow hair loss and how to I stop or slow it down?

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Unfortunately, many men and women experience eyebrow thinning as they age. It may just be age related, but it can also be an infectious process or a hormonal issue. Many also pull at their eyebrows, even without realizing it, and that can be a cause of the loss of hair as well.

Eyebrow transplants work very well in the right surgeon’s hands.

In the News – Hormone Replacement Therapy Increases Breast Cancer Death Risk – Hair Loss Information – Balding Blog

Snippet from the article:

A study published in the Journal of the American Medical Association confirms that postmenopausal women who take combined hormone replacement therapy (HRT) are at an increased risk of dying from breast cancer.

“Women on combined hormone therapy with estrogen plus progestin were twice as likely to die from breast cancer compared to women receiving placebo,” says medical oncologist and study author Dr. Rowan Chlebowski.

The researchers looked at more than 16,000 postmenopausal women who were part of a large government study called the Women’s Health Initiative.

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Read the full text at CNN – HRT increases breast cancer death risk, study confirms

This isn’t obviously about hair loss, but important information for the many women that read this site (or if your spouse, mother, sister, whomever is undergoing hormone replacement therapy).

Biopsy to Diagnose Telogen Effluvium or MPB? – Hair Loss Information – Balding Blog

Hi Dr. Rassman,
I really need your help. I am a 23 year old male who in the past several months noticed hair shedding. It’s all I can focus on now. Just recently I noticed the left part of my hair line is now thinner then the right side when seen under bright light. I would like to find out if there is a way to diagnose whether or not this is permanent or temporary hair loss. I’ve been to 3 dermatologists all who have done nothing but suggest Propecia. I would almost consider flying out for you to take a look. My question is, is there a definite way for you to say whether its permanent or temporary hair loss?

The shed hairs all appear to be very healthy with a white dot on the end. Is there a way to confirm if this is from telogen effluvium or MPB? What is the best method to diagnose TE or AGA? My dermatologist is recommending a scalp biopsy but I would prefer a miniaturization test since its less invasive. Is one test better then the other?

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If three doctors have diagnosed with you with MPB (hence the Propecia suggestions they gave you), I highly doubt I would have any thing more to add.

Statistically, a 23 year old male experiencing frontal hair loss would indicate male pattern baldness (MPB). A scalp biopsy will not tell you anything you do not already know… and in fact, it will leave a scar. We do not perform scalp biopsies for diagnosing standard hair loss. Telogen effluvium (TE) does no occur in patterns or localize only to the front, which male pattern baldness does. TE is diffuse and happens all over the scalp.

Also note that if you do have MPB, Propecia may help slow the progression of the loss, but it is not a cure and it does not work as well at the front of the scalp. As you indicated you are in NY, I’d suggest seeing Dr. Bernstein in Manhattan… or you’re welcome to setup a consultation and fly out to my office in Los Angeles. Unless your loss is more than what you described though, it seems like you’ve got early genetic hair loss and should probably follow one of the three doctors that advised you to start Propecia.

Are My Sexual Side Effects from Propecia or Saw Palmetto? – Hair Loss Information – Balding Blog

Hi, I was hoping you could give me some advise/insight re: my experience with propecia and saw palmetto.

I have been taking .5 mg of propecia and 160 mg of saw palmetto daily with excellent results, completely halting my hairloss with some strong regrowth, but I’ve encountered some sexual side effects – somewhat decreased libido, much less intense orgasms (where I’m barely even ejaculating at climax) and while I have no problem getting an erection, it’s not reaching the 100% max and most problematic is that my erection has been very flexible, which makes having sex much more difficult.

I stopped taking both the propecia and saw palmetto for a week and noticed all of the sexual side effects disappeared, but I felt a noticable thinning of my hair, so I’m hoping I can find a balance with the dosing, so I’m not shedding much hair or having the sexual side effects. Right now I’m taking the propecia and saw palmetto every other day, but still noticing the sexual side effects to a lesser degree, along with the thinning. Would you recommend cutting out the saw palmetto? Or any ideas on propecia dosing? Thanks!

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I sympathize that what you are telling me is what you may be experiencing, however, from a medical/scientific perspective it does not all fit.

  1. You do not notice immediate thinning after stopping Propecia in one week!
  2. Propecia or saw palmetto or any other herb or medication will not completely halt hair loss.
  3. Decreased libido may be from Propecia, but I haven’t heard of decreased orgasm intensity from Propecia.
  4. You cannot always blame a medication or herb for decreased libido, especially orgasm intensity. Maybe it is age related, partner related, emotionally related, etc.

I do not recommend anything other than discussing your issues with your doctor and getting a complete physical examination. Propecia is a prescription medication, so talk to your prescribing doctor that can offer you personalized advice.