Blocking DHT Type I and Type II – Hair Loss Information by Dr. William Rassman

Dr. Rassman,

DHT type II is found predominantly in hair follicles
DHT type I is found predominantly in the skin

Do you know if the inhibition of DHT type I can negatively impact the rate of skin aging? Pseudohermaphrodites offer a good biological modelf for type II deficiency, and I haven’t heard that they age any differently than men with normal hormonal profiles. But what about type I deficiency? Are you in contact with any dermatologists who might know about this, or at least have a theoretical response?

There are drugs that block both type I and II DHT, but they do not impact skin and aging. Biochemistry and the most logical scientific reasoning and models do not always correlate with what we observe. Blocking 100% of DHT (type I or II) does not stop or reverse hair loss and a 100% block of DHT is unlikely from a practical point of view.

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Facial Edema from Minoxidil – Hair Loss Information by Dr. William Rassman

What can we do about the facial edema we get from minoxidil? Is there any way to minimize or reduce the swelling, especially upon waking up?

Stop using minoxidil if you have developed facial edema from it. It may be a serious sign of an allergic reaction. You need to discuss this with your doctor, as there may be other medical problems you are not aware of.

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Fluticasone Propionate and Hair Loss – Hair Loss Information by Dr. William Rassman

I was reading some of your blogs and in “Sudden Hair Loss Years After Transplant” from November 23 2005 it makes mention of nasenx possibly causing hair loss. I am taking a similiar medication called Fluticasone Propionate, could this cause hair loss? I use it as directed which is 1 spray per nasal per day. I actually started it the same time I started Propecia which has been 4 months ago. I am 28 years old and MBP runs in my family. Propecia has slowed down the hairloss and hopefully I will see some regrowth in the near future.

I doubt fluticasone is causing hair loss. Fluticasone is a medication used for seasonal allergy. If you have been reading this site, you should know that medications (such as fluticasone) are the last on the list of the cause of hair loss. If you are losing hair, it may be due to male pattern balding in which you are taking Propecia for. You should get your scalp hair mapped out for miniaturization and get a diagnosis from a reputable and competent physician.

Partial Hysterectomy Has Left Me With Hot Flashes and Hair Loss – Hair Loss Information by Dr. William Rassman

I had a partial Hysterectomy in January 2007. My ovaries are still intact. For about 3 months now I have had tons of hair just break off at the scalp, I went to my gynecologist that performed my surgery he ran some labs and told me that my hormone levels are fine, but I am having severe hot flashes and daily hair loss(it’s coming out in clumps) It has me in tears and I used to have beautiful thick hair. Can you give me some helpful information, Please. Thank you

You need to be examined by a good doctor who understands hair loss in women. Hair loss is present in almost 50% of post menopausal women.

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My Hairline Has Matured at Age 17 – Does That Say Anything About My Future Hair Loss? – Hair Loss Information – Balding Blog

Hello,
I have read a few posts previous to my post, inwhich you reassured people that gaining a “mature hairline” at a early age (17 in my case), certainly DOESNT mean that you WILL definitely experience further balding past the “mature hairline”. on this subject i have two short questions:

  1. Is there any medical evidence based on maturing hairlines that states that they are definitely separate from the balding process (past the mature hairline)
  2. Since i reached a mature hairline at 17, does this mean i will have a greater chance to actually have the balding gene, or is this just me thinking the worst?

thanks for the great service you provide

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The answer to both questions is no, but a good Master Plan should be made with sound metrics on the mapping of your scalp for miniaturization to cover you in the future if you should develop hair loss.

For more about the maturing hairline, see Maturation of a Hairline — Moving From Juvenile to Mature.

Do DHT Levels Change Over Time? – Hair Loss Information by Dr. William Rassman

Dear Doc,
I was just curious to how the levels of DHT change in the body over time. Do DHT levels rise to some sort of critical level before the onset of baldness? or do the follicles just become less resistant to DHT as one ages? Also is there a difference in DHT levels in bald and not-bald males?

thanks

Yes, DHT levels change as we age, but the level of DHT does not necessarily correlate with balding or androgenic alopecia (AGA). It is your genes that makes you susceptible to the DHT impact on hair that produces balding. In other words, you can have a high level of DHT and if you do not have the gene for AGA, you will not lose hair. Or you can have a very low level of DHT and have the gene for AGA and be bald. As DHT comes from testosterone, it is your testicles that are the supplier of the hormones that cause baldness. If you did not have testicles, then the balding process would stop, but your hair would not come back.

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Enablex and Hair Loss? – Hair Loss Information by Dr. William Rassman

Hi,

I’m writing because my hair has been falling out for four months after I stopped the medication (Enablex) that I believe was causing my hair to fall out. Nowhere on the internet can I find an association with Enablex and hair loss and my doctor has not heard of this either. Do you have any knowledge of an assocation? I am sure this is the problem as the only other times my hair has fallen out is when I’ve been on other medications (Accutane, Zonegran). My hair stopped falling out in about 2-3 months after stopping the other medications but this time my hair continues to fall out at a rapid rate even though I’ve been off Enablex for four months.

Help! Is there anything I can do? Do you think it will stop falling out soon? Will highlighting my hair aggravate the problem?

I’m trying not to worry too much and be patient but I’m running out of patience. I already have straight thin hair and am worried I’m going to get bald spots soon!

Thank you

The Enablex website says, “Enablex is a prescription medicine that’s proven to treat the symptoms of Overactive Bladder (OAB).” Enablex (darifenacin) is an antimuscarinic that relaxes the bladder muscles to prevent urgent, frequent, or uncontrolled urination.

Hair loss is not a known side effect of Enablex; known side effects include dry mouth, constipation, abdominal pain, etc (see list). Even in the worst case scenario if Enablex was the cause, there is not much you can do to reverse the hair loss. Before thinking that this is the cause of your hair loss, you need to see if there are other medical conditions (including genetic balding) that is the source of your hair loss. The medication may just be a coincidence. I hope you consulted your doctor before you stopped taking the drug. You should never start or stop a medication without consulting with your prescribing physician.

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Lupron and Hair Loss – Hair Loss Information by Dr. William Rassman

A had a shot of Lupron in May. Since then I have noticed I am losing my hair. I have several areas where I can see my scalp. I was wondering if the Lupron was responsible and if it is permanent. Is there something I can take to reverse it? Thanks!

Many drugs can cause hair loss, but it is generally the last on the list of other more common causes of hair loss. Also, you should consider the medical reason why you are taking a certain medication. The medical condition itself may be the reason for hair loss. I cannot tell you why you are losing hair or what may be the cause, but Lupron is reported to produce hair loss, although it is an unusual side effect. You need to speak with your doctor and address these issues with him/her. Before starting or stopping any medication you need to talk with your physician.

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Make Your Own Laser Comb for Under $50 – Balding Blog

This is not an endorsement of the laser technology, just a video that some of you may find interesting and useful. No, I did not make this. The video was made by prolific Metacafe.com video blogger KipKay. For info on the HairMax LaserComb (the commercial product that sells for around $350 more), you can read the posts here.

Update: KipKay wrote in to let me know the video has been removed due to some apparently legal issue. Sorry, folks.


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Taking Propecia a Month After a Hair Transplant to Stop Shock Loss? – Hair Loss Information by Dr. William Rassman

Dr. Rassman

One month after HT I started Propecia hoping that it would slow down the shock loss that I am experiencing. Will propecia indeed contribute to helping reduce the shock loss?

Thanks for your help, this blog is a great resource.

It may help, but it isn’t in the ‘nick of time’ at this stage. You should have been taking Propecia before the surgery. It would not be a waste to take it now though.

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