Could Hair Cloning or SMP Work for Someone with DUPA?

Hi Dr. Rassman:

Once again, thank you for contributing to a great blog.

I am a 32 yr old white male with dark hair. Approximately 2 years ago I first noticed thinning hair on the Crown (about the size of a ping pong ball). I went on propecia and have been on it ever since. There has not been any visible progression (at least to the naked eye). In terms of family history, all of my immediate family members have their hair except once uncle in his 50s has a bald spot around his crown. My one deceased grandfather buzzed his hair but according to my Dad, still hair hair (not completely bald).

I went for a consultation with a hair transplant doctor who advised me that I would need around 2000 grafts to cover that space but since I have an unstable permanent zone (i.e. miniaturization) he did not recommend it.

  1. The doctor did not use the acronym “DUPA” but is that what he was essentially saying?
  2. I have had fine hair since I was in my teens. Is DUPA progressive or stable? I have what appears to be a full head of hair – will it stabalize here or continue to progress?
  3. Dr. Bernstein states that those with DUPA can look “fine” if they keep their hair very short. Does he mean short as in the same look achieved through scalp micro pigmentation?
  4. Can scalp micro pigmentation be of use to someone with DUPA?
  5. There has been a lot of discussion about hair cloning/manipulation being available commercially within 10 years (according to Dr. Bernstein). In your professional opinion, do you think such an advancement be of any use to someone with DUPA?

1. Genetic male pattern baldness doesn’t include the permanent zone, so diffuse loss there could be DUPA.

2. DUPA is often progressive, but it can be stable for a number of years. These conditions tend to be unstable if it is associated with genetic balding.

3. No, not that short. I am sure Dr. Bernstein means clipping it to 1/4 or 1/3rd inch.

4. It can be, but I do not like to generalize on this without examining your scalp and hair loss.

5. That 10 year mark has been moving every year. There’s no use speculating on what cloning can or can’t do for treating various issues, as it won’t be commercially available in the near future. If hair cloning becomes closer to reality, I’m sure the answers will come.

Could I Have BHT If I Plan to Keep My Hair Very Short?

I understand that you do not like the results of body hair transplants but do you think it would be an option for patients that were interested in keeping their hair cut very short and did not want the scar from FUT surgery?

Body hair transplantation (BHT) should be considered as a last resort (if you’re out of scalp donor hair, for example). It’s not just an issue of growth cycle, but the texture of body hair is different than that of scalp hair. The idea is to have the most natural looking result on your head, and I’ve yet to see anyone that has had BHT with a perfectly natural look.

If you don’t want the linear scar from traditional strip surgery, you can look into FUE, which uses scalp hair and would provide a better visual result than BHT would.

Could Hair Loss Be Due to External Causes, Rather Than Internal Causes Like DHT?

I read an article a while back that said resaerchers had found that acne was actually caused by a bacteria or fungal infection within the pores not an internal cause as previously thought.

Could it be, with Hair loss that resaerchers are only focusing on internal causes such as the DHT and actually overlooking other external causes like some kind of Fungal Folliculitis of the scalp that eats away at the folicles? Where does the DHT come from and why can’s we stop it?

Anything is possible, but the explanation you offered has not come to the forefront. I would not be surprised if there were other mediators for hair loss that make hair loss show up in one person and not another. We are not well informed enough to go there just yet.

This is what we know (taken from an article by Dr. David Whiting, a widely acknowledged leading researcher/dermatologist): “Testosterone and dihydrotestosterone can circulate systemically to follicles, or be manufactured locally in the follicle from circulating weak androgens (dehydroepiandro-sterone and androstenediol) via complex enzyme-mediated processes involving specific dehydrogenase and reductase enzyme pathways. All of these enzyme reactions are dependent upon specific pyridine cofactors. It is clear that reductase, dehydrogenase, and probably aromatase enzymes are of major importance in hair growth as they mediate the complex interchange of sex hormones implicated in anagen activity.

That is the biochemistry of DHT (dihydrotestosterone).


2007-09-11 14:33:08Could Hair Loss Be Due to External Causes, Rather Than Internal Causes Like DHT?

Could FUE Move Hair and Skin to Eliminate Scarring?

Dear Dr Rassman, please excuse my question if it is stupid. I’m not medically trained!

What is normally discussed is the movement of hair follicles *from* the donor site *to* the recipient site. And this inevitably leaves some form of scarring in the donor area. But is it technically possible (in FUE) to also implant skin *from* the recipient area *to* the donor area, in such a manner to “eliminate” scarring? i.e. for every follicle the surgeon would swap tissues A and B, where A would be the tissue originally at the recipient site, and B the tissue originally at the donor site.

I’m sure this would be more costly for the patient, buy I’m wondering: has this ever been tested? And would it eliminate scarring?

A number of years ago, a well-known doctor preached that small punch extractions of scars would produce “mini-scalp reductions”. It never worked. This sounds like what you are asking about, and if one removes scar from a scarred area, you just get scar to replace it. Not such a good idea.

By the way, there are no stupid questions. Your question reflects an inquiring mind.

Could My Hair Styling Wax Block Minoxidil from Working?

I understand your view on styling wax clogging the hair follicles not to be a cause of hair loss. However, I have been using the Nizoral 2% shampoo and wonder if my heavily waxed hair style (which doesn’t entirely wash out) could potentially block the shampoo from penetrating effectively into the scalp? Could this also be a concern for those of us on minoxidil?

What is on your hair does not impact the hair that is being manufactured below the skin, but with using wax, the barrier to the skin will prevent the minoxidil from working (and I suppose the Nizoral, as well). Minoxidil works below the skin, but it must have access to the skin to get through it. I tell people that they are best washing their hair before the application of the minoxidil.


2008-08-12 08:55:54Could My Hair Styling Wax Block Minoxidil from Working?

Could Iron Deficiency Be Accelerating My MPB?

I’m a male who has been diagnosed with Iron-Deficiency at age 20. I also have been noticing hair miniaturization and hair fallout from the top of my head (nothing from sides and back).

My doctor said the reason for this is the Iron Deficiency and I should correct it by multivitamins and minerals and then see if the hair fallout continues, since hair loss is a symptom of Iron Deficiency.

My question(s) is this:
– Would my deficiency be accelerating my inevitable MPB?
– Wouldn’t my deficiency result in hairloss all over my head instead of classic MPB fashion?
– Would correcting my Iron levels result is less shed, maintenance, or regrowth at all?

Thanks!

I don’t know what tests your doctor conducted to completely eliminate genetic male pattern baldness as a possible cause for your hair loss. If you’re losing hair in a classic pattern, you could have a combination of genes and low iron.

So to answer your questions — Yes, iron deficiency could accelerate your genetic hair loss. It may also cause thinning elsewhere on your head. Correcting your iron levels is important, but it may not impact the genetic patterned hair loss.

Could Minoxidil Change My Eye Color?

Hello Dear Doc

For hair loss i am using minoxidil 5% solution on my scalp and my eyes burn. Eye burning and irritation is known side effect of minoxidil and i wonder if it might change eye color?

There is a medicine named larissa which may change iris color used for eye lashes.

Thanks for your support.

I am not familiar with Larissa, but perhaps you mean Latisse (bimatoprost ophthalmic solution), which has rare reports of permanent eye color changes in people with blue/green eyes. Latisse is used to grow eyelashes and it is presently being tested to grow hair.

There are no reports with minoxidil changing eye color, but if you’re experiencing burning eyes after using it on your scalp (a common side effect), you should consider discontinuing use if it becomes too bothersome.


2011-12-13 13:26:31Could Minoxidil Change My Eye Color?

Could I Take Propecia To Slow Down My Unwanted Body Hair Growth?

Hello Dr Rassman,

I have been a long time reader of your site, and find your advice highly useful.

My question is: I am a 24 year old male. I am not suffering from any noticable hair loss (I think), but my younger brother is. I also have alot of body hair, esp on the shoulders and the back. Would propecia be useful as a proventitive measure, and slow down the growth of unwanted body hair as it is linked to DHT.

Regards

Propecia (finasteride 1mg) is not documented as a way to slow down body hair growth. This is your genetics working in its full glory. With that said, a couple of patients have reported to me a decrease in body hair with the drug.

Could Propecia Affect My Ability to Have Kids in the Future?

Hi Dr. Rassman I appreciate your website and blog very much I visit here everyday. I have been considering propecia for a month now. After searching the internet of course I have been scared like everyone of side effects of ed,low libidio,and I know your answer to this. Now I recently have been seeing everywhere on the internet about propecia affecting fertility! I mean I wanna have kids and start a family one day which out weighs having hair.

I am a 27 year old male and have some thinning and receding up top. So my question is if I take propecia is there any chance of it affecting my ability to have children in the future? Can you please set me at ease I realize you have answered this before

The information available shows that there is little risk to fertility from Propecia. If there is an incidence of drug induced infertility, it is very, very rare. What has been reported seems to reverse on drug withdrawal. Permanent infertility to finasteride does not appear to be a problem. If you are still concerned after reading this, when you take the drug for your hair loss, consider taking a sperm count somewhere after 3 months while you are on the drug.

Could My Recent Female Hair Loss Be From Anesthetic During My Appendectomy?

(female)
Recently i have been losing more and more hair so i decided to look at cause. I saw one was after surgery from the anesthetic. I had my appendix out recently. Is it possible my hair loss is from the anesthetic? Your help in this matter would be greatly appreciated. Thank you

What you are asking may be possible, but I do not know if that’s what is really going on. Trying to find personalized medical answers for a diagnosis on the Internet is common and I don’t blame you, but the best help I can give you is to recommend that you see a doctor (face to face) and ask them for a medical diagnosis after they examine you in person and take a detailed medical history.

Some patients (as you’ve seen online) report some hair loss after a general anesthesia, but there can be many other medical reasons for hair loss in women.