How to make your own topical finasteride, is it real?

Thanks Dr. Rassman. Any basis for why it will not absorb? Minoxidilmax.com one of the longest running topical finasteride sellers said this on DIY:

“If you want to make your own topical finasteride at 0.1 percent to save money, you should be able to do that with the right tools and material. No need to be a scientist to do so. The only tool you need is a scale that is accurate to 1mg level. All you need to do is to weigh 60 mg of pure finasteride power and pour it into a bottle of 60 ml minoxidil solution, close the bottle and shake it for 10 minutes.

The real challenge here is not how to make it but how to obtain good quality of finasteride material. Some people choose to use 5 mg finasteride pills (Proscar). In this case, you will need to pulverize 12 pills and then put the powder into a bottle of 60 ml minoxidil solution. Shake it very hard for 10 minutes. Let the bottle stand still for overnight and pour the clear solution to another bottle for use. The reason why it is recommended to dissolve the powder into a minoxidil solution is that it has right solvent that ensures the good absorption of the topical finasteride. You can’t just use pure alcohol as the solvent, because it evaporates too faster and you will end up with flakes of finasteride on your scalp that will never be absorbed.

With the 0.1% topical solution, you receive 1 mg finasteride if you use the solution once a day. If you use the homemade solution above twice daily, your finasteride dosage is actually 2 mg a day.”

This question is a moving target tied to instrumentation issues. Some doctors have done a) half FUE and b) half strip and measured growth differences and there were none. There are certain patients that FUE will cause damage, that group is a subset of those I called Fox negative patients in my original article. This group of Fox negative patients has contracted to a smaller number because of better and better instrumentation that has developed over the years. In that small sub-set of patients, there is no doubt that FUE is an inferior surgery and that sub-group, unfortunately, can’t be identified in advance, so each individual takes some risk that they may be in this sub-group when they elect to get FUE. Maybe this sub-group is 5% of all FUE patients, maybe less, but for them it is 100% less quality surgery because there is more damage to the grafts during harvesting. This presents the problem as if it is black and white, but there are gray areas in this sub-group that may make the sub-group larger than 5%. The strip doesn’t have that risk.


2020-04-19 15:14:50How to make your own topical finasteride, is it real?

How you can protect yourself from Corona Virus

https://pubmed.ncbi.nlm.nih.gov/32035997-persistence-of-coronaviruses-on-inanimate-surfaces-and-their-inactivation-with-biocidal-agents/

What is very significant is this statement: “human coronaviruses (HCoV) can persist on inanimate surfaces like metal, glass or plastic for up to 9 days” so it is important to be aware of this and when you can clean a surface, follow the directions in this article.

How to Transition from Taking Propecia at Night to Taking it In the Morning?

Hi,

I’ve been taking propecia in the evening for a little over 2 months now. I have read your comments that state it is better to take propecia when you wake up and I was wondering what the best way to make the transition is. Should I skip a dosage at night then take it when I wake up and continue taking it in the morning after that?

Just take one the next morning. A 50% increase in the dose for one day will be insignificant in the management of your hair loss.


2007-01-12 10:11:30How to Transition from Taking Propecia at Night to Taking it In the Morning?

How Will The Doctor Know To Diagnose My Female Hair Loss?

well i have this thinning problem for the past 4 years. it was started when i conceiving my daughter 4 years back. i was prescribed chronostim for my hairloss and i used it for 2 months and my hairloss stop for a year (2005). the problem seems to show again about a few month ago roughtly on January 2006. the hair loss is diffuse and can be seen clearly on the crown. i started using minoxidil a month ago and my hair still falling.

To be honest i would like to have the hair transplant for the crown only so that it can look more dense.

my question is whether i am the right candidate for the hair transplant?. how will the doctor know that my donor area is not affected by AGA since females always have a diffuse thinning?

A doctor should look at your donor area with a hair densitometer to look for miniaturization. The greater the miniaturization, the worse the donor hair will be for hair transplants.

The important thing to understand is that women are generally not good candidates for hair transplantation, because the ‘donor hair’ is not healthy. If there is an area of good donor hair and the balding area is small enough to make a difference with a limited supply of your ‘good’ hair, then hair transplants MAY work, but you run risks that include the failure of the hair to grow enough to make a difference, and even experiencing hair loss with the transplants (this a real risk). You need to be able to trust that the doctor is not just taking your money for a quick sell, leaving you no better or even worse off once you empty your purse.

How to quantify your donor area hair supply?

Here is a picture of the donor area of a man who asked me: How much donor hair do I have? He asks: You have talked about the Donor Bank in your writings, so I would like to know how many grafts are in my Donor Bank and what will be my lifetime supply of grafts for hair transplants in case I should become very bald?

First let’s see where the permanent zone of hair can be found. It is called the permanent zone because even the baldest of men, never lose hair in this zone (see photo below). The zone measured from 2.5-3 inches in height and extends around the entire head from temple prominence on the right side to temple prominence on the left side. We generally assume (safely so) that this hair will always remain (regardless of the balding pattern a man develops). Back in the late 1950, a doctor ‘Orentriech’ discovered that if this hair is moved anywhere on the body, even into a bald area of the scalp, it would grow as it would have grown in its home location in this permanent zone. That is why it is called the permanent zone of hair.

There are two important numbers to determine from the hair in this zone (1) the hair count per follicular unit (these are the groups of hairs that contain one or more hairs each in them) and the thickness of the hair shafts of this permanent hair (never look at the hair you are losing as normal hair as it often gets thinner and thinner). I quantify the thickness of each hair shaft in the permanent zone by feel (experience helps here) or with a micrometer as Fine (~40 microns or less in thickness), Average (~60 microns in thickness) or Coarse (70+ microns in thickness).

I generally take a picture of the donor area with the hairs cut short enough that I can count the number of follicular groups in the field of view and how many hairs are in each group (see below). This field of view of the donor area of one of my patients was taken with a purchased lens as an attachment for my cell phone (https://www.amazon.com/gp/product/B07S5YPPQX?pf_rd_p=ab873d20-a0ca-439b-ac45-cd78f07a84d8&pf_rd_r=CCSSMZGDS79G6AG31TT9) at a cost of $16, something you should consider purchasing.

First let’s do some simple math: There are 34 individual hair groups (in the area shown in the photo) which contain from one to 6 hairs each (each are counted and labeled for you). The total hair count in this field is 85 hairs. If we divide the number of hairs by the number of groups 85/34= 2.5 hairs per Follicular unit (a Follicular Unit is essentially what we call a Graft in a hair transplant surgery). The average Caucasian has 2.2 hairs per Follicular Group so the man shown here has a hair count that is 13% higher than average. I can tell from this number that this man has 125,000 birth hairs on his head regardless of how much hair he has already lost. I felt his hair for thickness and measured it. It measured 60 microns which is essentially an average weight hair.

Now let’s look at more detail at this picture. There is a single hair shown that I labeled ‘m’ for a miniaturized hair. So this man had approximately 1% miniaturized hairs. The number of miniaturized hairs can be as high as 20% and the donor area is still considered healthy. As we get older (into your 50-90s) these hair groups may drop hairs so that the count could be slightly lower and the hairs that we often drop will often be miniaturized before they fall out. Everyone experiences hair changes with age, as donor area hairs may get ‘finer’ so that they contain less hair bulk per hair shaft. If these hairs are used for a hair transplant, whatever happens in this permanent zone, will happen in the hair transplanted hairs as well.

The calculations of his total donor bank supply is a bit more complicated. Each person has a fixed number of Follicular units (about 50,000 for an average sized head). Generously assuming that the size of the donor area is between 20-25% of the total hair baring scalp (let’s use 25% as a number for calculations here), this patient has 31,250 hair in his permanent zone or 12,500 follicular units (grafts) of which he can transplant theoretically no more than 60% of these hairs (follicular units or grafts). The 60% number is based upon an average hair count, but because this man has 13% more hair, he can actually move 13% more grafts bringing his total available lifetime hair to 7,500 * 1.13 = 8,475 grafts available during his lifetime.

Experienced surgeons like me who have been measuring hair densities since I first entered the practice and defined it in the literature, have learned when they can increase even this number safely. This is where surgical judgment comes in. I would like you to try to make this important assessment of your Donor Bank so that you will be able to (1) test the doctor’s knowledge of what he says about your donor supply, (2) be confident that your donor quality and quantity is adequate to meet your short and long term hair transplant needs.


2019-12-17 11:59:26How to quantify your donor area hair supply?

How to Tell if You’ve Found the Right Hair Transplant Doctor

What is the difference between doctors and the various medical groups performing hair transplants. There appears to be a great deal of competition and as I go between groups, I get confused and overwhelmed.

If you were looking for a good family doctor or plastic surgeon, you would most likely use certain criteria for selecting one over the other. Fundamentally, you would look for a well credentialed, caring, competent doctor who you like and feel comfortable with. Be sure that the doctor values you as a patient by spending time with you and discussing your agenda freely. Ask yourself if the doctor listened to what you were saying or lectured you about his/her ideas. That doctor must be trustworthy to take on your welfare or your family’s welfare, and not only must you believe in his/her skills, but you should also like him/her as a person. Although the various family doctors and plastic surgeons use physician’s assistants or nurse practitioners to help them manage patient’s needs, the doctor is always ultimately the person in charge, the one whose skills you will eventually depend upon. As most doctors practice in groups, you should feel comfortable with the doctors who work with your doctor in the group that you selected, as sometimes your doctor may be on vacation or off-call when you need him/her the most.

You should expect that physician extenders should be educated as physician extenders (nurses or certified physician assistants, not salesmen). Hair transplantation differs from standard family practice and cosmetic surgery procedures in that there is a team approach to performing surgery. Doing refined follicular unit transplantation takes a team of 3-6 people working together for hours, so the doctor’s team is as important as the doctor is. An old cliché says that a chain is only as strong as its weakest link, so the skills of the doctor as one link of that chain can easily be offset by inexperienced technicians in the surgical team or sloppy processes that are not put together carefully and not focused on the many detailed nuances that produce quality hair transplants. You should feel confidence in the doctor and the team and you should feel ‘integrity’ and trust in soul of that doctor.

In my hair restoration practice, I add many elements to build confidence and establish trust. I have an open practice, where new, potential patients can meet completed hair transplanted patients one-on-one. This offers the opportunity for new patients to probe the process and see up front what they will be getting if we perform the surgery. I focus heavily on patient education, not only by providing copies of some of the important medical articles I have written, but also in spending time with each potential patient (doctor and patient in a private room without a salesman). Then after the visit, I provide a detailed letter summarizing what I learned about the patient’s objectives, and a written Master Plan for what I think will happen to that patient. Fees are openly discussed by the doctor and quotes for surgical fees are put into writing. By far, most of our patients do not have surgery and can be spared surgery with appropriate medications.

NHI is unique in that we have a fully accredited surgical center where all of our surgeries are performed, ensuring safety for patients to the highest national standard. Our surgical center is audited regularly for following hospital quality processes and procedure. Very few (if any) hair transplant facilities adhere to such rigorous standards. Why is that important? Well, it is the patient’s assurance that our sense of quality is judged against the best healthcare facilities in the nation. When you select a medical group for your hair transplant procedure, you should not only know the facility, the staff competence, and longevity of that staff, but also the history of the doctor. Has the doctor been disciplined before the medical board for infractions in any form of conduct? What does the public and his colleagues think about the doctor (available through internet sources)? What is the doctor’s malpractice record? Have you met or spoken to his/her former patients, and if so, what do they tell you about their research prior to taking on this doctor as their doctor-of-choice?

I always tell my patients (and have written on this blog many times before) that there is good news and bad news for the hair transplant patient — simply put, hair transplants are absolutely permanent. Getting it done right the first time is far easier that trying to fix what might not be fixable if it is done wrong. By following this selection process, finding a good doctor should not be difficult. There are many good doctors out there, just be careful not to end up in the wrong place.

How Visible Are FUE Scars if I Shave My Head?

Does having an FUE procedure to hairline and mid scalp make it artistically unpleasant to shave your entire head? I like to wear my head closely cropped, but I’m unsure if the punctate scars from FUE are extremely visible when you closely shave your head

There are many variables that produce different scars with follicular unit extraction (FUE). These variables include:

  1. The size of the punch used (ranges of punch sizes are from 0.8-1.5mm). The larger the punch used, the bigger the scar.
  2. The density of your donor hair dictate the visibility of these scars. Low density donor sites tend to show the punctate scars more than individuals who have high density.

What I am referring to here is shaving your head bald, not clipping it to a #1 length. Shaving the head will almost always show the punctate scars. There’s an extreme photo example shown at this page to give you an idea of scarring from a large FUE session.

How will the HAIRCHECK instrument tell me whether or not the follicle will stop growing?

The HAIRCHECK instrument measures hair bulk. Follicles that stop growing do not add to the hair bulk on your head. Everyone with genetic balding will show patterns of reduced hair bulk when this is measured. I answered this in past tense. If you are asking me about the future, I don’t have any way to predict it. If you have genetic balding, then it is almost a guarantee that you will see more and more of it as you get older. see photos here on use of HAIRCHECK instrument: https://baldingblog.com/2017/01/10/value-haircheck-bulk-measurements-two-patients-seen-today/

Huge central necrosis from hair transplant

This was a complication arising out of a hair transplant performed by unskilled technicians in Turkey. The patient most likely was a smoker. This complication is called ‘Necrosis’ which means in this situation, all of the skin in the area that is now an open crater has died. Fortunately, he either sloughed off the dead skin or a surgeon removed it. I will eventually heal with a huge scar and transplants into the scar may correct the defect after everything has settled down.