Oral Minoxidil and its potential side effects (article)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678755/

Please note the following statement in the article:

Since the original introduction of low-dose oral minoxidil for this indication, reported adverse effects have been purported to be infrequent and of minor impact, with 15.1% hypertrichosis, 1.7% lightheadedness, 1.3% fluid retention, 0.9% tachycardia, 0.4% headache, 0.3% periorbital edema, and 0.2% insomnia reported in the largest retrospective multicenter study so far of 1404 patients, leading to drug discontinuation in 1.2% of patients.”

The focus on the Pericardial Effusion is significant as it appeared in a woman with a low dose of 1.25mgs/day. So the kew here is to watch for the following symptoms as they appear:

Shortness of breath, discomfort while breathing in the supine position, chest pain, lightheadedness, and swelling in the legs

Any medication can have serious side effects. Aspirin for example, has killed people from allergic reactions, bleeding from long term use, etc.. For those of you who take oral minoxidil, just be alert to the warnings in this article.

Oral minoxidil

How often do you see such dramatic improvements using oral min among your patients? Thanks

It occurs often. I only started prescribing it a four-five years ago, and I have been more than surprised with the results

Oral minoxidil 2.5mg for one year (photo)

This is a wonderful response to Oral Minoxidil 2.5mg daily that I prescribed for one year use. Most of his frontal hairline had disappeared but returned with the oral minoxidil.


2021-09-17 11:25:37Oral minoxidil 2.5mg for one year (photo)

Optimal Age for a Single Hair Transplant?

Dear Dr. Rassman,

Thank you very much for your helpful book and web site. I am a 29 year old male planning to get a hair transplant. You have recommended waiting until the thirties before getting a transplant due to the risk of shock loss before hair loss has slowed.

One question I have is does using Propecia push back the age in which shock loss is still a risk? Since Propecia generally slows the hair loss process I would think that the age in which hair loss stabilizes would be later. Can a hair transplant surgeon figure out whether shock loss is a possibility just by examing your hair?

A second question, if I were interested in getting just one transplant in my life, what would be the optimal age? Or, if I were willing to get two, what would be the best times? Again, is this something that a surgeon needs to address on an individual basis?

Thanks so much for your help!

Propecia will certainly slow down the timeline for your hair loss. Shock loss does not happen following surgery in most men who are taking this drug. There’s no guarantee though, and determining the risk isn’t something that can be done by an exam.

I generally tell patients to wait until at least the age of 25 before considering a hair transplant, but questions about the ideal age reflect where you are in the balding process and if it bothers you. There is no ideal age for a transplant and only your needs should be a consideration. Be sure that you are on Propecia first and for everyone else reading this, if by chance you are under 25 years old, then trying the drug for a year is very important in building a Master Plan for you.


2010-02-18 10:52:37Optimal Age for a Single Hair Transplant?

What Is Your Opinion of All the HT Doctors Based in Turkey? They Seem to Get a Lot of Great Reviews.

There are over 500 clinics in Turkey bringing in over $1 billion per year. Of the 500+ clinics, over 90% are illegal without a doctor in the facility doing the surgery or the anesthesia. Many clinics perform multiple surgeries in a single large room, risking a cross-over of germs or even HIV from one patient to another. Production line hair transplants should be avoided as they are not bargains. Some of the good clinics with a good doctor do good work, but many of the clinics do variable quality work, many with infections reported by my European colleagues and deaths that are never reported. Just be careful and make sure that there is a doctor doing the surgery who has a good reputation.


2019-02-20 07:02:41What Is Your Opinion of All the HT Doctors Based in Turkey? They Seem to Get a Lot of Great Reviews.

Oral Antiandrogens for Female Hair Loss

Hi
I was wondering what your opinion is of this study? Thank you!

Treatment of Female Pattern Hair Loss with Oral Antiandrogens

I referenced this article before — Treatments Available for Female Hair Loss

The conclusion of the authors suggest that there is merit in the use of antiandrogens, but the study is not statistically significant. Since my earlier reference 2 and a half years ago, our ability to separate women into two classes (those who are sensitive or not sensitive to antiandrogens) through the use of new genetic tests holds great promise for the future management of women’s hair loss. It is possible that in those women who had the best response to antiandrogens are women who have a high sensitivity to the antiandrogens as determined by genetic test (see HairDX). The study should be repeated with the genetic groups separated.

Oral Minoxidil has a rare cardiac risk on a very low dose of 0.25mg/day

A recent report out of South Africa showed a healthy woman placed on 0.25mgs of oral minoxidil developed cardiac and other systemic swelling. This situation could have been life threatening, but it was picked up early and the medication was stopped. The problems went away.

Up until this point in time, I, like most of my colleagues believed that dosing oral minoxidil of 2.5 mgs/day or lower did not expose the risk of cardiac complications. This is the first such reported case of what may be thousands of people, but this post is here to let you know if you are on oral minoxidil that this is a risk.

Of significance, this patient had signs of a problem with swelling of the legs, hands and face and her doctor was quick to discontinue the drug with reversal of all side effects , so if you get swelling of your hand, feet face, speak with your doctor and consider stopping the minoxidil.

Oral Minoxidil Side Effects (From Reddit)

Oral minoxidil can cause: (1) a dry cough, (2) sharp stabbing chest pain, (3) chest pain spreading to the arm or shoulder, (4) nausea, (5) sweating, (6) general ill feeling, (7) trouble breathing (especially while lying down), (8) swelling in your legs, ankles, or feet, (9) rapid weight gain of 5 pounds or more, (10) light-headed feeling with occasional fainting, (11) low blood pressure. Every medication has its side effects. These are not frequent.


2018-06-19 09:51:59Oral Minoxidil Side Effects (From Reddit)

Oral minoxiidl at 1mg, is this effective?

My derm prescribed me 1mg oral minoxidil as they wanted to evaluate the effects of the drug for a month before they increase the dose. I am wondering if 1mg is effective enough and if anyone has seen results when taking 1mg? I currently use topical minoxidil 2 times a day.

Since 60% of men will not respond to topical minoxidil, the oral works on 100% of men. The 1mg dose is a reasonable starting dose. Your dermatologist knows what she is doing.

Oral Minoxidil?

I have been a long time fin user and recent Dutasteride user for the last few months. I’ve already spoken to the guy that’s done my dysport for years about trying oral minoxidil. I’m not interested in using it topically and have read some really encouraging and really recent literature lately on low dose oral Min for MAA. Is this a reasonable option?

Oral minoxidil can be very effective and is a good alternative to finasteride


2020-09-15 12:16:40Oral Minoxidil?