Any Data for 2mg Finasteride Benefits?

I understand that a 1mg dose of Propecia is recommended. What I want to know, however, is how much more hair grew at a 2mg dose vis-a-vis the 1mg dose — 10% more? 15% more? I know these data exist. So, what incremental improvement might there be with a 2mg dose?

While it’s quite possible that the data for 2mg finasteride hair loss treatment benefits exists, I don’t have it, I don’t recall seeing it, and I’m not sure if it was ever made available to the public.

I do know that there were studies that looked at high dose and low dose finasteride (prior to Propecia becoming available) for treating hair loss. More is not better and I am not aware of a 2mg study showing any additional benefit. The stories that I do hear are anecdotal.


2011-01-28 09:19:26Any Data for 2mg Finasteride Benefits?

Another Hair Loss Following Pregnancy

I have experenced hair loss after each one of my pregnecies. I have three kids,while I was pregnant my hair was fine. I have seeked medical advise, I was told stop having kids. Can you tell me if hair loss after pegnancy will ever correct itself, in other words will it grow back?

Some doctor’s amaze me with ridiculous comments like, “Stop having kids”. Hair loss with pregnancy is common and most women who experience it, like you, will see the process reverse within the first year after birth of the child. Have as many kids as you want. The hair loss, unfortulately, may recur with each pregnancy on a non-permanent basis, unless you have genetic female balding.

I answered a similar question about a week ago, found here.

Antioxidants and Free Radicals

Although this post isn’t hair loss related and it is about an article that is nearly 2 years old, this is an important read for those who buy into the antioxidant solution to anti-aging, heart disease, stroke, cancer, and the like. The question raised here is whether you can get these antioxidants from pills or do you have to get them from fresh fruits and vegetables?

Snippet from the article:

Cranberry capsules. Green tea extract. Effervescent vitamin C. Pomegranate concentrate. Beta carotene. Selenium. Grape seed extract. High-dose vitamin E. Pine bark extract. Bee spit.

You name it, if it’s an antioxidant, we’ll swallow it by the bucket-load. According to some estimates around half the adults in the US take antioxidant pills daily in the belief they promote good health and stave off disease. We have become antioxidant devotees. But are they doing us any good? Evidence gathered over the past few years shows that at best, antioxidant supplements do little or nothing to benefit our health. At worst, they may even have the opposite effect, promoting the very problems they are supposed to stamp out.

Full text at NewScientist — The antioxidant myth: a medical fairy tale

Anxiety, Mood Swings From Propecia?

I have been talking propecia for about two weeks and I have been experiencing wierd side effects like anxiety attacks, feeling out of it, slight mood swings, etc. However, when I asked my doctor about it, he said that he had never heard of anything like it. There are a number of people online who have complained about similar side effects and I feel that these symptoms are a direct result of propecia. I was wondering if you had ever encountered any similar cases and if so will these side effects go away. Thanks

Finasteride blocks the conversion of testosterone to DHT. As a result, there will be a temporary increase in testosterone and changes in androgens as well which might (theoretically) produce side effects like those experienced by women with PMS. One of my patients had a real complaint like this and he was a very credible physician. When he stopped the Propecia the symptoms went away. Can hormonal imbalance affect mood swings? Possibly! Some patients have repored changes in the way they feel on Propecia and I have generally discounted these report but now I will make a note of this and watch for more patient comments and blog emails that bring this up. I aleady spoke to a Merck rep about it and hopefully the verbal report will work its way back to headquarters. If I hear more of these type of complaints, I will be more vocal on sharing this with you through this blog.


2006-04-19 20:22:49Anxiety, Mood Swings From Propecia?

An Answer to a Patient’s Questions

Dear Dr. Rassman,
Thanks for taking the time the other day to visit with me and also for the very informative follow-up letter and your recommended plan for my hair transplantation. Over the last two months I have been seriously looking into the hair restoration field and have read three credible books and studied every web site of every accredited hair doctor. I also consulted with doctors that I felt were very respected in hair restoration. My conclusion is that I need to stay on Propecia consistently to preserve the hair I have right now and use the follicular unit transplantation (FUT) technique exclusively, to replace the lost hair.

But I am confused by the number of grafts recommended. So far, I have heard various numbers ranging from 1,000 to 3,000. After visiting with you and hearing your recommendation of 2500 grafts, I wrote back to a very reputable doctor who had recommended a session of 1,500 grafts and told him that another clinic had recommended 2,500 grafts. He then told me that 1) each person has very limited donor supply and one must plan a session based on future hair loss, and 2) the survival rate of transplanted grafts deteriorates as the number of them placed close to each other is increased, as is done in megasessions. He told me that other clinics have no guarantee or refund policy if the hair follicles don’t grow back, so they just transplant as many as possible, even if not safe for the patient.

So my questions are:

  1. What does ‘limited donor supply’ mean in my case? You saw my hair, how many good donor grafts in total do you think I have for now and the future? What would it be if Propecia did not work and I continued to lose hair?
  2. Have you seen any side effects with larger sessions such as more noticeable scar in the donor area, loss of transplanted grafts, excessive swelling of the forehead or longer recovery periods?
  3. Do you or can you guarantee a certain survival rate for the transplanted grafts?

I appreciate the time you have taken to help me with my hair loss problem. I guess I can’t help it, I am a natural engineer, and this being the most important decision I probably ever make I have just been researching the hell out of it! I am confident, however, that I am talking to the best source there is out there.

Part of what is important about being a doctor is the concept of mutual respect. The person who wrote the email to me on this blog, is analytical and clearly fully aware of the subject material. Good communication produces respect so a doctor should spend an appropriate amount of time and focused attention to address your concerns at the interview and in followup to that interview. I would welcome a call from you to elaborate on this blog answer.

  1. Some people do not have the donor supply and when that will be an issue, I tell them. The amount of donor hair is a calculation of density in the donor area plus laxity of the skin. Finally, the size of the bald area and the final worst case pattern must be taken into account. As measurement is critical to this process, one must make direct measurements of the density in the donor area. I was the first to publish on the measurement of the donor supply and the instrument I invented to do this is now used by every competent doctor in this industry. There are no other instruments that are used for hair measurements that do not fall under my U.S. Patent. The average patient has about 6,000-12,000 grafts to move but the wide spread reflects the many variables discussed above.
  2. If you come to our free open house events, you will meet people who had thousands of grafts and see for yourself what happens. The key to understand the safety of large sessions is to meet directly with many people who had them. I would not be doing large sessions if they were not as good or better than multiple smaller sessions. With good decision making by the doctor, large sessions should not scar more than multiple smaller sessions but there may be a cost for aggressive decisions in large session transplantation if the doctor is not experienced in such procedures.
  3. This type of complaint usually reflects the act of denial which most people exercise when they forget what they looked like ‘before’ the started the hair restoration process. Sometimes, people continue to loose hair and think that the new hair loss reflects a transplant failure when it really reflects the unpleasant idea that balding continues. To address the growth of the transplanted hair, wWe guarantee our work. Anything that does not grow, we will replace at no charge. This almost never happens, so I rarely discuss it unless asked.

Application of minoxidil, finasteride and the use of Dermaroller (called “The Big 3”) from Reddit

This is a combination of treatments commonly used by many young men on the Reddit post. There is evidence that minoxidil plus the Dermaroller works by itself to some degree but adding finaseride makes is a more certain response as shown here after 5 months of use.


2019-02-12 06:40:17Application of minoxidil, finasteride and the use of Dermaroller (called “The Big 3”) from Reddit

Any Adolescent Hairline Transplant Photos?

Can you post a before & after photo of someone who you’ve lowered their hairline to an “adolescent hairline”. I know you’ve said in the past you usually only do this procedure on someone who makes their living by their looks & I wanted to see how much of a difference it would make. Thanks, great blog!

These three patients had their central hairline brought down to the childhood hairline position:

Also, please take a look at the hundreds of patient before and after photos on my website in the Patient Photo Galleries.


2006-10-23 14:52:22Any Adolescent Hairline Transplant Photos?

Any Point in Taking 5mg Finasteride to Treat Hair Loss?

Dear Doctor,

I just wanted to know if there is any point of taking 5mg proscar for hairloss? From my research I think the answer is no but I have taken 5mg for last 6 weeks. I have noticed a lack of motivation and being a bit down but I am not exactly sure if they are related to taking the 5mg or due to other things in my life. Could there be any side effects for taking for the 5mg for the past 6 weeks? If I just cut down to the quarter Proscar tablet (1.25mg) will my body take long to readjust after having taking 5mg dosage?

Thanks you for your time,

Kind regards

There is no point in taking finasteride 5mg (Proscar) for treating hair loss. Aside from the increased side effect possibility, it will not work any better for hair loss. I really cannot comment on your lack of motivation and its relation to the medication. Maybe you have the holiday blues? Side effects from medications should generally reverse in about a week or two.

Another Depleted Donor Area (Photo)

Over and over again, patients are getting a see-through donor area from over-aggressive donor FUE harvesting. There is a limit on how many FUE grafts can be harvested, and your doctor has an obligation to tell this to you.


2018-06-19 09:27:16Another Depleted Donor Area (Photo)

Any Photos of Transplanted Younger Patients with Advanced Balding?

Hi Doc,
Could you be able to post some photos in HT on younger men (30-40) with advanced balding patterns (class 6 or higher) in your blog or at NHI site. I am 32 years old south asian considering HT with NHI, but I havent been able to find how younger patients fare with HT.
Thanks for this great blog.

Take a look at our patient photo galleries on the NHI site. There’s over 300 patients shown there with thousands of pictures. There are many young men on the site that fit what you’re asking for. I used the search box and found these to get you started: Patient LT, Patient EE, Patient XG, and Patient MU.

If you come to one of our Open House events, you will actually meet some men in their late 20s or early 30s who have been transplanted.


2012-03-12 10:51:18Any Photos of Transplanted Younger Patients with Advanced Balding?