Hair Loss and the Immune System – Hair Loss Information – Balding Blog

I recently read a posting on baldingblog where a women suggested the use of Visine to stop hairloss. I’ve heard of using visine to help sooth razorburn an ingrown hair as I assume it has antiflammatory medication.

I’ve read other places that some people think hairloss is a type of immune response of our body, where DHT causes the structure of the hair follicle to change. At some point our own immune systems reject the changed follicle and attack it, ultimately causing the phenomenon we see as balding. Somewhere else I read that in cases, such as people getting transplants take immune suppressing drugs such as Cyclocsporine, to stop organ rejection, actually noticed hair regrowth.

Going back to the woman who earlier spoke of the Visine treatment that she heard, this woman said that her hairloss got worse after she moved. Speaking from my own experience, I have noticed that certain immune responses happen when one changes environment. For instance, I grew up in New Jersey and never suffered any real allergies or medical problems. When I moved out to California when I was 16, notice an increase in my hyper-histamine.. or histamine positive response. I believe thats what you called it. In particular, I developed an allergic reaction to heat.

Anyhow, its interesting to think that environment may have a small role in a complex immune response that results in hair loss.

Is hairloss a more modern occurrence? I mean, does hairloss occur more in modern society? I remember reading an article recently in Wired that said that when comparing lab mice with sewer rats, the sewer rats had “better” immune systems because of their dirty environment. The immune systems of the lab rats tended to overreact to stimuli. On the other hand, the sewer rats immune systems better defended against real threats while not overreacting to things such as allergens. ( http://www.wired.com/news/wireservice/0,71185-0.html)

Anyway, thx for your blog, Dr Rassman. It’s always interesting and entertaining!

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I agree with you that although hair loss is caused by genes, it can be influenced by the environment where chemical products, drugs, malnutrition, and stress can induce the expression of balding genes. Hair loss is not a modern society occurrence. Men have been bald since the beginning of recorded time. Hats and wigs have been around since the earliest records in the history of civilization.

Are we more self conscious with hair loss today? Somehow I doubt that, but we do have better communication (like this blog and the internet in general) to share what is happening to us with others. We do know that autoimmune diseases can cause hair loss by creating antibodies attacking the hair follicles, but that may not mean that hair loss is always an immune modulated disorder. A famous doctor told me once that sooner or later (he predicts) that we will learn that every disease entity will arise from either infection or genetics. At this point though, who really knows?

Hair Loss From Long Hair? – Hair Loss Information – Balding Blog

Hey Doc
I noticed when i started to grow hair out ive been losing strands of hair quite easily. My hair is about 3-4 inches long now, and i have a couple questions:
1. Because im growing my hair out does that mean its easier to fall out/ more noticible when it falls out?
2. And it appears that im losing hair from all sides of my head, basically every where the back, the top the sides exct. so does this mean that this is not male pattern baldness since there is no pattern to it?

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This could be that because of the long hair, its easier to fall out or pull it out with styling. Therefore, it will be more noticeable when it falls out as you suggested in your question.

It is also important to know that hair length is a reflection of the length of the hair cycle and each person has a different hair cycle lasting on average between 2-7 years. As hair grows at 1/2 inch per month, just calculate length over time. If you hair cycle is short (1 year) then every hair on your head will cycle every year (just an example here, as most people have at least a 2 year hair growth cycle).

If you are losing hair on the sides and back of your head, it may not be male pattern baldness, but could be an infection or disease. To be sure, and not cause yourself more worry, you should have your hair and scalp mapped for miniaturization so you and your doctor can know what is going on.

My Head Got Bigger? – Hair Loss Information – Balding Blog

hi there.
im a 17 year old boy who is worried about receding. i have a full head of hair but it is a bit thin in the left hand side at the temple. i have been told it has always been like this. my mothers dad went bald before 30, my dads dad did not go bald. but my dad has receeded a bit on top. when my hair is dry u cannot see my scalp but when wet it parts alot and seems thin!!also i was told that my head may have got bigger which may make it seem like it has receded! am i worrying over nothing??

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Growing boys with growing and maturing heads, do not thin out their hair. You should get your scalp mapped out for miniaturization to find out if you have early genetic hair loss.

I Lose Hair Transplant Grafts in My Sleep – Hair Loss Information – Balding Blog

I had a hair transplant last night and this morning I found grafts on my finger nails along with blood clots. My transplant surgeon told me not to worry about them after I said that there were about a dozen grafts that I could count. He said that he did not have to see me. What would you do for me in this situation?

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ReclinerI had a patient who picked his head in his sleep, just like you seemed to do. Knowing this, I had his wife make him wear ski gloves in his sleep the rest of that week. I did view the patient, but as the grafts had been already out of his body for hours, there was no point to put them back as they would not have grown. The grafts on this patient came from the crown, where he had 1500 grafts placed by me. He had about 10 grafts lost and they did not appear to be significant, considering the large number that we placed there.

I had another patient leave the office after the surgery and from the edge of the limo, he scraped the scalp removing about 150 grafts in the car’s gutter. We quickly retrieved them and washed the grafts with saline and put them right back into his head. Fortunately, the time out of the body and into the saline was only a minute or two. The grafts grew, but I think that we all had anxiety over this one.

I do not use bandages to cover the recipient site and I tell my patients the importance of keeping their hands off of the head and recipient area. I generally like a person to use a recliner chair for the first and second night, to keep the head elevated and make it more difficult to scratch the recipient area when they sleep. I have not had a problem like the ones I spoke about for over 10 years.

Born Without Pubic Hair! – Hair Loss Information by Dr. William Rassman

I was born without pubic or underarm hair, I have eyebrows but they never grow long. The hair on my head is thick and lustrous – other body hair sparse. What causes this?

There are genetic patterns that each of us inherit associated with both our heritage and our ancestry. American Indians, like their Asian ancestors, have very little body or facial hair. Many Asians do not have pubic or under arm hair. We have transplanted many Asian women who want pubic hair, but it will grow like your head hair, a bit more curly, so you will have to cut it to keep it short.

For your eyebrows, it sounds like you have very short hair cycles there, which means that the eyebrow hair may only be there for a very short time when it falls out and eventually gets replaced by other hairs. When this happens, the length is usually very short and the growth rate is always slow in the eyebrow, possibly slower on you then in many other people of similar ethnic background.


Hair Loss InformationIs Hair Always Uniform Over the Head of a Non-Balding Person? – Hair Loss Information – Balding Blog

I’m a 24 year old male, and I have a family history of balding. I have close-cropped hair, and I noticed that I can see a bit more scalp in the “runways” along the sides of my head and around the crown than I can see on the top of my head. The individual hairs in the thinner areas do not actually seem to be miniaturized compared to the hairs in the thicker areas, which is what confuses me. It looks like there are just fewer overall hair follicles in the thinner areas. It may have always looked like this and I never noticed, since I never thought to check until my brother started balding. My front hairline is not receding at all. Could this be a normal (non-balding) hair pattern, or is hair always completely uniform over the entire head on a non-balding person?

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There are two independent measurements that will point to what is going on. There is the actual hair counts by area and miniaturization by area. Both of these metrics can be obtained when you map out your hair for miniaturization. I do not always do hair counts in all of the areas I map, but in your case, this might be worthwhile.

Genetic hair loss causes both miniaturization (thought to be a precursor of balding, but not always) and direct reduction of hair counts without going through the miniaturization process. What you are viewing should have numbers put to it so that the diagnosis is in hand answering the basic question: Do you have genetic balding going on?

Most people will have some variations of densities by the part of the scalp, and these differences do have some consistency in the population. Hair along the sides is often less dense than hair in the very back of the head, for example. Yesterday however, I met a man who had just the reverse — a higher density on the sides, less in the very back. Good baselines are critical to understanding your hair loss, and good measurements in the hands of a good doctor will reveal that information for you.

Accutane Hair Loss is Permanent? – Hair Loss Information – Balding Blog

Hello Dr. Rassman last you told me to go to a doctor in ny, I went to see him but he stated that he just didn’t know. I a 3rd round of accutane over 2 years ago, and have experienced hair thinning since.. I am very distraught since I thought the ny doctor could give me more answers and explanations as to how accutane could possibly damage hair follicles forever. I’ve been researching but its all about people like me complaining aobut the accutane induced hair loss, but no reason how it could do this damage. I was told that accutane works by reducing your sebacous gland. I had no idea that sebum would play a role in thinning or damaging hair.. I don’t know why doctors are saying it can be permanent, when in the past they said its only temporary.. and its been over a year, my hair is so thin. I’m taking biotin and I’m not even sure if that will work. I have no one to turn too. Can you explain to me what needs to be done, or how it can damage the hair follicles, if accutane only effects the sebacaus glands. thanks.

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Medical clinical science is as much a descriptive science as a biological science. That means we describe what we see, possibly more than we understand what we see. Do not be too hard on the doctor, because I am sure he told you what he knows. As for scholarly doctors, that doctor is as scholarly as they come. We know that Accutane does, at times, cause permanent hair loss (that is what we see) but if we really knew why, then we could surround the cause of it and maybe fix it. I do not have the answers you are looking for, nor do others I have asked. Sorry!

Is Missing Facial Hair a Side Effect of Rogaine? – Hair Loss Information by Dr. William Rassman

I have been using Rogaine 5% topical solution regularly for about 6 years now. It has worked marvelously for preventing the thinning of my hair at the back of my head.

Just recently I noticed two large, circular patches on my chin and neck where facial hair no longer grows. I grow a goatee and didnt mind the two empty patches but now another small, circular patch has developed in my goatee area. Could this be a side effect of using Rogaine?

Thank you for any assistance you can offer.

I would worry more about alopecia areata or fungal infection as a cause, which require a good doctor to make the diagnosis. I would doubt that this is a side effect of Rogaine.

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My Hair Loss Became Aggressive Quickly, Follow-Up – Hair Loss Information by Dr. William Rassman

Doc,

I wrote in a few days ago about receding hairline: “My Hair Loss Became Aggressive Quickly.” I gaurantee I have what is “minimization.” I can see like at least an inch deep into my hair in the front but not on the sides. I am dirty blond like you asked, but I cannot imagine it is 90% gone. 50% maybe. Now I am on day 10 of Propecia. So according to the literature, from here, I have ~80 days before I see any “changes,” if I see any at all. From what I’ve read about Propecia, the more hair you have there, the better it works. So, say I go from 50% to 60% (for instance) by the time this stuff really starts being effective (the 80 days), are my chances of getting my full thickness back LESS than if i started a month ago? Two months ago? Could it be happening that quickly? I mean I started with propecia when it was 50%, right? Which number matters, the number now or the number later? Is propecia really working this whole time, but its just not “noticeable” for 3 months? Or should I assume things will continue to get worse (thinner) before they get better?

Thank you.

If you keep counting down the days for Propecia to take effect you’re going to lose your hair out from the shear stress. Remember, Propecia will take at least 8 months to see the benefits of it working. More importantly you may STILL lose your hair even on Propecia. Propecia may help by slowing the rate of your hair loss. I have no way to tell how fast or how much.

It seem you are very concerned and perhaps even obsessed with your hair loss. You may consider seeing a dermatologist or even a hair transplant doctor for your questions and concerns. Make sure that no one sells you a surgery without, in your case, waiting out the results of Propecia. Having a quantitative (not just your estimate) measurement of your hair by mapping your scalp for the degree of miniaturization may help you and your doctor in documenting the efficacy of your Propecia therapy.

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Chemical Damage? – Hair Loss Information by Dr. William Rassman

Hello Dr. Rassman. I experienced a sudden hair loss and breakage from strong chemicals. In the months since ive stopped using the chemicals there has been no further hair loss. But a few days after putting the chemicals on my hair I noticed that 1000’s of hair strands were markedly thinner. Is it possible that a chemical could just shrink the hair shaft permanently? Also the texture of my hair is different. If I stopped using the chemicals would my texture and hair shaft diameter return to normal or would the follicles continue to produce thinner and finer hair shafts?

I have addressed this question in a variety of forms (see: chemical damage). Please note that even though you think the cause is chemical, there is no substitute to getting a good examination in the hands of a good doctor who can look throughout your scalp at the condition of the other hairs on your scalp that do not seem to bother you.