Can I Stop Propecia Eventually as Testosterone Levels Decrease Over Time? – Hair Loss Information by Dr. William Rassman

Hello Doctor ,

I have been taking propecia for 6 years with a great success , but i am close to 30 years now , and i was wondering if i could stop it now. Don’t you think that with our Testo levels decreasing over age (about 2% per year after 30) , the DHT levels will decrease too, so that we could stop the propecia by getting older ?

Good thought, but taking Propecia is not directly related to testosterone levels. Propecia affects DHT levels, and even DHT levels do not tell the full story. For example, even with high testosterone levels, you can have NO hair loss. Conversely even with low testosterone levels you can have massive hair loss.

The root of the problem (pardon the pun) for hair loss in men is genetic, not DHT. As such, there is no definitive cure. But if Propecia is working well for you to this point and you have no problems, why stop it? In reality, you should never stop taking it, as long as you wish to retain your hair.

Balding Forum - Hair Loss Discussion

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Castration and Hair Regrowth – Balding Blog

From what I have read, castration stops hair loss however, castration will not regrow hair that has been lost. If this is true, why would Proscar grow any hair? It is my understanding Proscar blocks a percentage of DHT, which leads to the effectiveness of the product. If someone has been castrated there is o% DHT and still no hair regrowth? Also if DHT causes hair loss why is Propecia effective on the vertex of the scalp and not the temples.

There is a wide audience of young men (over a million) who have taken Propecia and we know that in the very young man with active miniaturization, the process may be reversed. This occurs mostly in young men in their 20s. I would guess that if we castrated 1 million men who are balding in their 20s, that the incidence of regrowth would be higher than those on Propecia alone, but I am not recommending castration as this is only an intellectual exercise.

When a hair is dying (miniaturized hairs fall in this category), like a dying person, they have a chance of being fixed or cured because they are not dead yet. When a hair has completely disappeared, it has gone through apoptosis, which means that the hair growth center is dead… and we all know that you can’t raise the dead. This applies to hair when the head is slick bald in any area impacted where there is no miniaturized hairs.


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Hair Loss InformationSaw Palmetto Claims, Finasteride Pricing – Hair Loss Information – Balding Blog

Dr. Rassman other than stating that sal palmentto has not been proven to block DHT. Do you have a professional opinion to the clams of many who have benefited from taking Sal Palmentto?I have been taking Propecia for years and stopped hair loss. However I must cease buying Propecia due to economics and have been looking for a clear honest opinion.
Thank you

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Saw palmetto may help stop hair loss, and you’re welcome to try it, but it is not certain that it does what people on the internet claim. In my professional opinion, it has not been proven to be effective.

We all know that generic drugs cost less than the name brand, but there is no generic 1mg finasteride available legally in the US at this time due to patent laws. So ask your doctor for a prescription of the 5mg generic finasteride and let him/her know that you’ll cut it into 4 pieces (making it nearly the same as Propecia). This will be a significant savings for you. The cost of the 5mg generic finasteride at Costco is $5/month, which is possibly cheaper than saw palmetto and with more certainty that it will work.

Hair Loss InformationProlactinoma and Hair Loss? – Hair Loss Information – Balding Blog

Hi Dr Rassman,

Im looking for a bit of advice, i think i have been fooling myself into believing i was going bald genetically and that my hairloss was due to Seb Derm/Inflammation and Traction loss. I believe some of it has been caused by my scalp picking and itching, but i have noticed i am starting now to recede and have lost hair diffusely through the top and also on the sides of my head.

I have been diagnosed lately with a Prolactinoma and low Testosterone so dont know how much that could be affecting my loss if any ? if im just going bald DUPA what would be youre recommendation for halting and regrowth, and would it conflict with my Cabergoline im using to shrink my Pituatory Tumor ?

Thanks

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You’ve got a lot going on. The excess production of the hormone prolactin can possibly cause hair loss, but I do not have a lot of experience in this area. I can’t give recommendations for you, as I don’t have enough information and you’re under the care of a doctor that you should be getting your info from. Cabergoline doesn’t list hair loss as a side effect, and I’ve written about a similar problem before here.

Hair Loss InformationStem Cells, Hair Loss Treatment, and Politics – Hair Loss Information – Balding Blog

I was curious what you’re views might be on stem cell research legislation and how political decisions might impact future progress, since stem cell therapies seem to hold the best promise for a cure to baldness. From what I have read, restrictions placed on research during the socially right-leaning Bush years have set cures back by years. Again, just wondering how you think the political climate can/will affect a cure or better treatments for things like baldness.

Thank you

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PoliticsAlthough there’s enough political tension in the news lately to cause me to not want to delve into policy talk, I can avoid this topic fairly easily as I really have no idea about the political climate for stem cells. While it is an interesting question, I don’t even know that stem cell therapies hold the most promise to be first across the finish line in cure development. There’s rumblings from Histogen about their stem cell therapy being available “as soon as” 2013, but it could just be more wishful thinking. I recall people supposedly in-the-know saying, “hair cloning will be available within 5 years” — and that was a decade ago.

Timelines in treatment development are constantly in flux during the early stages and I wonder if some of those target dates are hinging on everything going right on the first try. In a perfect world that might be the case, but the reality is that there is a lot of trial and error and many promising technologies never get beyond the development phase. With all that being said, if I had to guess I’d say better drugs will get us closer to the elusive hair loss cure.

Hair Loss InformationIn the News – British Singer-Actor Will Young’s Experience with Propecia – Hair Loss Information – Balding Blog

Snippet from the interview:

I love my hair – my barber, Paul, has given me a 50s style with a bit of a quiff. I take Propecia pills for my hair, because I started losing it four years ago. It’s a horrible thing – it’s emasculating and you just feel you aren’t sexy any more. The pills worked and my hair grew back, but I am sure they’ll stop working.

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Will YoungRead the rest at — What I see in the mirror: Will Young

I honestly had no idea who he is, but apparently he’s quite popular across the pond. Wikipedia says he won the first Pop Idol show, which is the precursor to American Idol. Look, I have a tough enough time staying current with all of the US celebrities!

At any rate, I’m sure someone will find this interesting, at least for the fact that a celebrity is going public about taking his hair loss medication and seeing results.

Hair Loss InformationHistogen HSC Available in 2013? – Hair Loss Information – Balding Blog

Dr. Rassman, I found out this update from Histogen, what is your opinion on this?

Videos: Histogen’s HSC – Highly Anticipated Hair loss Treatment Due to Hit “Shelves” As Soon As 2013

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HistogenI know nothing more about the Histogen HSC (Hair Stimulating Complex) than you do by watching those videos. I do give credit to Dr. Naughton for appearing in the videos, but I always worry about market hype and speculation in such announcements. I doubt we’ll see it move through the pipeline as quickly as hoped, but we can all keep our fingers crossed that I’m wrong.

Hair Loss InformationFinasteride Transdermal Patch? – Hair Loss Information – Balding Blog

It occurred to me that there is no reason that the finasteride clock has to be based on a 24-hour clock. I work for JPL and we use an elongated day in order to plan rover activities on Mars. This means that the days are longer than 24 hours.

I have developed a titre-method that maintains an average daily dose of 1mg of finasteride using quartered proscar pills. Take 1.25 mg every 30 hours as such:

Sunday: 6am 1.25mg
Monday: 12pm 1.25mg
Tuesday: 6pm 1.25mg
Thursday: 12am 1.25mg
Friday: 6am 1.25mg
Saturday: 12pm 1.25mg
Sunday: 6pm 1.25mg
Tuesday: 12am 1.25mg
Wednesday: 6am 1.25mg
Thursday: 12pm 1.25mg
Friday: 6pm 1.25mg
Sunday 12am 1.25mg

But why go through all the trouble? Why hasn’t anyone developed a transdermal patch or implanted finasteride device to main a constant titre? Is this hard to do?

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ClockI commend you on your scientific reasoning and approach, but I must point out one flaw: human beings are not computers and can be somewhat lazy in nature. We have a hard time keeping to a set schedule no matter how simple it may look on paper. Can you remember to brush your teeth exactly at a certain time? Maybe it would be a different story on Mars, but it’s hard enough to get someone to take one pill just once a day. Compliance is the issue at hand. One more thing which may be a bit more important — the half life of finasteride is about 4 hours. To maintain a constant level, the presence of the drug will deteriorate on a minute by minute basis so you might need to actually take 0.125 mg per hour or 0.00209 mg per minute. Try that for a compliance model.

A transdermal finasteride patch is a good idea, but there needs to be money, clinical trials, special drug formulations, and pharmacokinetics to make that work. Who will be willing to put up that research and investment when the cost of Propecia itself (in a simple pill) is cost prohibitive for many men?

Hair Loss InformationI Can’t Get an Erection After 2 Weeks on Propecia – Hair Loss Information – Balding Blog

Dr, please respond to this email I am in desperate need of help. Im a 21 year old with a rapidly receding hairline. I was prescribed propecia and and took it for 2 weeks. I know it seems impossible but after a week on it I almost completely lost my ability to get an erection, both during sex and masturbation. When I finally get one it is extremely weak and doesnt last long. This has never in my life been a problem before. I’ve been off the medication for 3 weeks and the problem has not resolved itself. What can I do?

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I can understand the desperation, but I highly suggest you go back to your prescribing doctor to help manage the problem. Sexual side effects occur rarely (1 to 2 percent), and many men can manage the process with their doctors including reducing the dose, or by stopping it to study what happens when the drug is withdrawn. Many times this side effect will go away over a month or so. If your libido is there, then drugs like Viagra may help while you try to work through the problem with your doctor.

I realize the Internet is filled with strange side effect stories. The strength of some of the most prolific campaigns to predict loss of libido or erectile dysfunction can become highly suggestive for the young reader of these bulletin boards.

Hair Loss InformationPreferred Topical Hair Loss Treatment – Hair Loss Information – Balding Blog

what do you prefer in MPHL (male pattern hair loss) in topical solution? Please also tell me the percentage that you recommend for its treatment? And also for how long its therapy has to be taken.

Thanks. Waiting for your reply.

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For a topical solution I recommend 5% minoxidil, which should be used twice a day. However, Propecia (finasteride) is the best treatment if you are actively balding, but that is a daily oral pill. If you wish to maintain the benefits from the treatment, you must stay on the medication forever (this goes for Propecia or minoxidil).