Hair Loss InformationIs Propecia Making Me Lose My Quick Wit? – Hair Loss Information – Balding Blog

Two questions here,

  1. Can Propecia be taken before bed at night instead of, say, in the morning, or during the day?
  2. I saw some post about someone mentioning grogginess as a side effect of taking Propecia. I consider myself a pretty silver-tongued guy, sort of along the lines of Dane Cook. I speak relatively fast and somewhat witty, I’d hope. When I take Propecia I feel like I trip over my words more, thereby causing me to lose some of that quick wit. Does this make any sense or not?

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Dane Cook

  1. Once a day, anytime, will work for Propecia (finasteride 1mg). I generally suggest to take in in the morning when testosterone is highest in men, but I really do not have any figures on that, just my logical mind.
  2. There have been some reports on depression with Propecia, but I don’t know if your quick wit can be dulled by the medication. I haven’t had any reports from my patients about feelings of disorientation or foggy-headedness, but I had one person that I can recall wrote in a while ago saying they felt a little foggy when on Propecia (though it is unsubstantiated).

Do I Need to Use Saw Palmetto Forever? – Hair Loss Information by Dr. William Rassman

Hey Dr. Rassman, I was just wondering if I took saw palmetto and saw some results and then stopped using it, would that have the same effect as taking propecia and then stopping its use. I know after one stops taking propecia all that hair is lost, would that be the same outcome of stopping saw palmetto?

Thanks

If the claimed DHT blocking occurs with saw palmetto, then I suspect that if/when you stop it, the maintained hair would be lost under the exact same mechanism as Propecia (finasteride).

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Does Minoxidil Inhibit DHT? – Hair Loss Information by Dr. William Rassman

Interestingly, Provillus’s website states that, “Minoxidil, the only ingredient clinically tested, and approved by the FDA for restoring your hair, inhibits DHT.”

I thought finasteride was the only FDA approved DHT blocker and minoxidil was something else. I’m confused.

Short answer — no. I am unaware of any inhibition that minoxidil has for DHT. Minoxidil works differently and not on the formation of the DHT hormone; finasteride does block DHT.

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I’ve Been Taking Finasteride and Minoxidil for 9 Years and My Hair Continues to Thin – Hair Loss Information by Dr. William Rassman

I’m a 31 year old male who has been losing his hair for approximately 9 years. My hair has suffered diffused thinning throughout the entire top – in a Norwood 6 to Norwood 7 pattern, however my hairline remains intact, albeit with very fine hair.

I’ve been consistently on finasteride and minoxidil through a majority of the past 9 years. However, year by year, month by month, my hair continues to thin.

My question is as follows: For the time being my hair remains very thin, but with an extremely close cropped haircut, I don’t look THAT bald because of the fact that I still have coverage (as thin as it may be). In your opinion, will continued treatment with rogaine and propecia help me maintain this thin hair or is my continual thinning a sign that these drugs are not helping me?

A response is appreciated. Please don’t tell me to have my hair mapped. Been there, done that. I’m losing it.

You will continue to lose your hair if you have been thinning for all these years despite your daily doses of Propecia (finasteride) and Rogaine (minoxidil), but it is safe to assume that these medications will continue to support the hair you have left. I suspect it is helping slow the balding/thinning process down. If you still have a hairline and are just thinning behind it (with fine hair in general) it does not sound like you have a problem now and are more worried about later on. If you can delay any surgical decision, it may be in your best interest to do so, but without a direct examination of you, I can not ascertain what you need.

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Hair Loss InformationCan’t Take Finasteride, Follow-Up – Hair Loss Information – Balding Blog

I want to reference: Can’t Take Finasteride, But Is a Hair Transplant Still an Option?

Dr Rassman,

Thank you for answering my original enquiry. Whilst i understand that one your goals is to protect patients from over enthusiasm for a HT. But is a HT something you would do on a 22yr old male who can’t take finestaride. I ask this before one fly’s across the globe to see you for a consultaion.

Thank You

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I can not tell you for certain that I would do a hair transplant on you without knowing your donor density and doing a miniaturization study to determine (if possible) what your projected hair loss is. Knowing your supply and demand potential and your density and laxity, I would then make a decision on a hair transplant on you. So if you can’t or won’t take Propecia (finasteride 1mg), it does not 100% rule you out, but I first need to make that assessment.

We can arrange a call after I receive good photos of you and base some of this evaluation at the time of a telephone consultation. To setup the telephone consultation with my office, you can fill out our handy web form and you’ll be contacted via email to complete the setup.

Hair Loss InformationHow Fast Does Hair Loss Occur? – Hair Loss Information – Balding Blog

Hi Dr. Rassman,

First, thank you for making this blog available. It’s great and tremendously helpful. Here’s my situation: I am 25 years old. My 65 year dad has major baldness and my mom’s brother have had issues with balding too, so my future is not good. My hair was normal until a year ago, when I graduated from university and got a job that’s stressful. Since then, my hair has been disappearing. The crowns are rising and my thick hair has become thin… losing about 40% in volume already.

Does balding happen this fast? And is it all this stress that I’m dealing with? I thought I’d have normal hair until my 30s, but I have to deal with this now unfortunately.

Thanks

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If you have genetic hair loss, you should map out the scalp and hair for miniaturization and then (assuming you are genetically balding) go on finasteride (Propecia), which will slow down and possibly even reverse the hair loss you are experiencing.

There’s no one true answer to each of your questions. Everyone loses hair at different rates and stress can certainly accelerate it. Seek out medical attention, as the earlier you start treating it, the better will be your future with the hair you still have left.

Propecia’s Male Breast Cancer Risk – Hair Loss Information by Dr. William Rassman

Hi, I’m thinking of taking propecia (my trichologist has advised that I would benefit from taking this medication) but, from reading your site I’ve just noticed the issue about risk of male breast cancer. My mum has had breast cancer and I’m concerned that this could cause problems for me now if I start taking propecia. Could you give me some advice on what to do as up until this point I was happy with taking the drug!

There have been two cases in the medical literature of male breast cancer reported with a patient on Propecia. The incidence of breast cancer in men as about 1% of female incidence. This alone may account for the finding in those two patients. It is not a high risk issue, even for those with a history of female breast cancer in the family.

Hair Loss Information12.5% Minoxidil? – Hair Loss Information – Balding Blog

Hello. I recently came across a website claiming to sell Minoxidil 12.5% solution. Do you know if this is legit? I haven’t heard of the FDA approving such a solution, and if it is available on this one particular site, why isn’t it available at major drug/retail stores? Also, same question for 5% minoxidil solution w/out propylene glycol (which irritates my scalp)also “allegedly” available at this site. I just don’t want to get scammed if I do decide to purchase either of the above products. Thanks a lot for your time and information.

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Note: I can’t really answer your question, as I have not researched the FDA issues and am just pulling from my general knowledge on the laws by which I practice under. That being said, I’m willing to take a stab at it…

Doctors have the ‘power’ to mix up medications for their patients under many state laws. These do not have to be FDA approved because they are not bottled and sold to the public. The FDA does not get into protecting one patient from one doctor, just lots of people from medications. The doctor should generally use medications that are safe and effective and if one doctor is producing 12.5% minoxidil, I would suggest that this doctor has special knowledge on the safety and effectiveness of this drug. Higher and higher doses of minoxidil can drop blood pressure, so it is not without risk when and if it is used. The same applies to the use of propylene glycol in the mix.

A couple years ago, I had a reader write in with a question about 15% minoxidil he could buy from his doctor, so apparently that is also available in some places. I don’t concoct my own minoxidil mixtures, so I’m not unfortunately not the most knowledgeable about this.

Do I Need to Be on Propecia Before an FUE Procedure? – Hair Loss Information by Dr. William Rassman

I have been losing hair for a long time now. I am 42 and want to start taking propecia. I am also considering FUE. I keep my hair really short (Setting 1 on clippers). My question is do I need to be on propecia before i get my fue procedure done. Will the doctor prescribe me propecia after my procedure. Can I avoid propecia if i get a FUE procedure.

You do not need to be on Propecia before any hair transplant surgery, but in most young men I recommend it and suggest that it is started as early before the surgery as reasonable (minimum 2 weeks). Generally though, it is always a good idea to minimize shock loss and also to minimize further natural hair loss with Propecia. The decision to go on a medication or even surgery is highly individualized to your particular situation, and you need to discuss all these pros and cons with your doctor.

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Hair Loss InformationCatch-Up Hair Loss, Finasteride, and Hair Cell Suicide – Hair Loss Information – Balding Blog

Hi, Dr. Rassman.

You’ve written a number of times about the “catch-up” loss that happens when a patient discontinues finasteride/propecia. I know you didn’t design the drug, but I was wondering if you know how this catch-up process works.

What I have a hard time understanding is this: If androgenic alopecia is a gradual process of miniaturization, why doesn’t that process-when you stop the drug-just pick up where it left off at the start of therapy? It seems like something must be getting worse “behind the scenes” during the course of therapy. Is it known what that something is?

I hope that made sense. Thanks!

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Propecia (finasteride 1mg) sustains scalp hairs that are genetically susceptible to falling out. It does this by a process of competitive inhibition. When the drug is no longer available, the DHT is manufactured by the body and it ‘attacks’ the hair follicle which is like turning off the ‘life’ switch of the dermal papilla cells (which manufactures the hair follicles).

Once you stop taking the medication, you will not lose all the hair at once, but the ‘attack’ will occur over a few months. The hairs that were being supported by finasteride will go back to its pre-destined state, which is something called apoptosis (these dermal papilla cells that generate the hair follicle commit suicide — just die off).

For more about apoptosis, see ResearchApoptosis.com and Wikipedia.