Hypoandrogenic Reaction to Propecia – Hair Loss Information by Dr. William Rassman

what are the questions one would ask a doctor if he wanted to be sure he wasnt having a hypoandrogenic reaction to propecia? what would a doctor check, or know to find this out?

im a 25 year old male and ive been on propecia for 15 months or so. Hair has thinned quite alot while on treatment, instead of second guessing myself and reading to many websites.

i just want a medical answer! thanks for the help doc!

You need to tell your doctor what you are experiencing. Testosterone levels transiently go up with Propecia as compensation to the impact of DHT blocking. Are you asking if developing breasts is a problem with Propecia? Your questions are not clear.

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Is Merck Suppressing the Cloning Cure for Balding? – Hair Loss Information by Dr. William Rassman

Dr. Rassman,

What is you take on the idea of companies like Merck trying to suppress a “cloning cure” for balding, with all this huge amount of money being made on drugs like propecia?

Do you think that this might be preventing a cure for hairloss because in the end its all about the money.

Thanks

HollywoodYour question is like a set up for a ridiculous Hollywood movie “conspiracy theory”. I hope that you asked this question in jest.

Merck, like all drug companies, are entitled to make money (a return on its investment) from its research in the drug development process and they can not possibly conspire to stop progress. The rewards for cloning hair and the riches that will be derived from finding that magical cure, will be reward enough for anyone cleaver enough to solve the cloning problem. Did you know that it costs about $800 million to take a drug from development to the market? It also takes about 15 years where the money is consumed on things like tests and trials. Without a profit, they would stop creating new miracle drugs for all of us that improve our lives.

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Body Size of Patients Used in FDA Trials on Finasteride? – Hair Loss Information by Dr. William Rassman

Hi there,
Can I just say that you have a great site! I’m a regular reader, and think that I have a question for you that may be interesting. I’ve searched through your archives and haven’t found a similar question, but if I have missed it, please accept my apologies.

Recently I have had a look through the FDA trial reports on finasteride, but cannot find any information on the body sizes and characteristics of the patients used in the study. Are such data available? (Histograms, Mean/median, SD, etc).

Whilst I am assuming that the effective dose of finasteride for treating MPB is related to body size, and that the occurrence of side effects increases with relative dose, could there be a case for smaller dosages being suitable for people smaller than the people used in the FDA study – Asians and orientals for example? As this blog is international, I feel that we “vertically challenged” of the rest of the world need to know! :)

I passed your question to Merck and I just got an answer. Essentially, the only thing that was studied was the average dose that is effective and it was not related to a person’s weight. Body size was not studied.

Curis Hedgehog Agonist Hair Growth Program Terminated – Balding Blog

BusinessWire – Curis Provides Update on Hedgehog Agonist Hair Growth Program

This press release shows us the difficulty to bring a “hair loss cure” to market. Much hope had gone into the possibilities that this new treatment for hair loss could bring, but ultimately, it did not meet safety requirements for Procter & Gamble, who collaborated on this product with Curis.

From the press release:

Procter & Gamble has notified Curis that it has decided to terminate the collaboration agreement with Curis because the Hedgehog agonist compounds under development pursuant to the collaboration did not demonstrate an acceptable safety profile. Pursuant to the collaboration agreement, the agreement will terminate in six months.




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Minoxidil Destroying My Hair Texture – Hair Loss Information by Dr. William Rassman

Dr Rassman,
I have been using Rogaine for more than a year now and it had done nothing to my hair loss, actually it increased the rate of loosing my hair plus destroying its texture. My question is; if I stop it now, will it get worse and I would loose more hair, as I have read some blog about huge shedding after stopping Minoxidil ?

Thanks for your help

If you have been using minoxidil for a long time and stop abruptly, you may experience some hair loss for whatever hairs may have been benefited. There is no way to tell how much hair loss (if any) would occur. If you did not see a dramatic increase in your hair growth from minoxidil, I doubt it would have much impact if you stopped using it.

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Finasteride at 1mg and 5mg Dosages – Hair Loss Information by Dr. William Rassman

Is propecia at 1mg as effective as finasteride at 5mg ? thankyou

What was published in the original work on Propecia was that the 1mg dose was just as effective as the 5gm dose for treating hair loss. One might suspect that there is a dose response relationship and that a higher does might have more of a benefit than the 1mg dose, but that is strictly guess work. I only know for sure what I read about the subject and that data is well documented in the literature and through the FDA approved trials.

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Is More than 1ml of Minoxidil More Effective? – Balding Blog

minodoxil/rogain in liquid alcohol based form is to be used twice a day 1ML each time. What are the effects in terms of B.P or any other side effect if the drug was used in slightly more capacity (say 1.5 ml or even 2ml each time) to cover a larger area over a long term period. Will it have any adverse effects in the long term? or patients are strictly advised to use 1ML twice a day? in short is more than 1ml minox more effective?

Some people just can’t tolerate higher doses of minoxidil. You could try a higher dose and see if it makes you light-headed. If it does, then the dose could be too much. There is a suggestion that a higher dose of minoxidil is more effective and some doctors make up their own formulations in the 15% range. I do not offer this, because I have no experience making up medications in my office.




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Is There a Rogaine Pill? – Balding Blog

What are the effects of taking rogaine and propecia together? Are any positive effects negligible? Does rogaine only come in topical form (no pill)?

Minoxidil was originally an antihypertensive pill that did not have a consistent response for the treatment of high blood pressure. It grew hair on some of those who used it. It is not recommended today for oral use in the treatment of hair loss. It was more effective growing hair when it is applied to the skin directly and is certainly safer.


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Propecia and the G-Spot – Balding Blog

Dear Dr. Rassman, I have a question about Propecia’s impact on the prostate. I’ve read other posts but have not been able to find anything regarding my particular question.

Like women, men also have a g-spot and it’s located on their prostate. My question is, if Propecia shrinks the prostate does it impact the g-spot too? For better or for worse? Will it make the g-spot disappear? Thanks.

Your question is an interesting one. I do not believe that men have the same type of G-spot that women have, but the nerves that surround the prostate in men are in the same vicinity as where one would find the G-spot in women (just above and behind the pubic bone). Propecia will not shrink a normal prostate, only one that has benign swelling from age. I do not know if there is a perceptible difference in the feeling of a swollen prostate and one that is less swollen (I might venture a guess, but not here). Gay men who have anal intercourse or digital stimulation may be better able to answer this question if they are in the upper age group. Having done many rectal examinations and having had them myself during my annual physical examination, I know what it feels like to have pressure put on the prostate (I do not particularly like it, nor do most heterosexual men).




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Hair Loss InformationAminexil vs Minoxidil – Hair Loss Information – Balding Blog

Hello,
can you please explain the difference between “Minoxidil” (Regaine) and “Aminexil” (Dercos SP94)? I am having troubles choosing between these two products.
Many thanks.

Block Quote

Aminexil is made by the large cosmetics company L’Oreal and is reported to act in a similar manner as minoxidil. As L’Oreal is behind it, there is an aura of credibility to it. Aminexil is not tested according to the FDA, so there is no way for me to judge from reading the material if there is value similar to minoxidil, as stated in the various publications I read.