Is DHT Essential For Genital Function? – Hair Loss Information – Balding Blog

Is DHT essential for proper genital tissue structure/function?

(more detailed: could lack of DHT lead to decreased AR expression in penile tissues & nitric oxide production… leading to tissue changes, ie fibrosis/collagen deposition which cause such shortening/lack of bloodflow?)

I know there is relevant posts to this issue where you dismissed finasteride in relation to a change in penis + testicle size but i thought it was important to bring forward my case to show that there is definately some relation with finasteride and penis size *in a flacid state*, aswell as testicle size. I am a 20 and a half yr old male who has been on propecia since about 19.

id like to point out im not saying that my penis has actually reduced in physical size due to finasteride, but in its flacid state it now resides alot different to how it use to – doesnt hang as much, looks like ive come out of a cold shower – which in turn gives the apperance of a smaller penis.

what ive experienced:
– testicle/scrotum shrinkage. they are no longer hanging as low as they use to, they are now tight and pulled very close to the body. scrotum could almost be described as empty and wrinkly
– reduction of how penis resides in flacid state. In the flacid state my penis is ALOT smaller then usual. penis doesnt “hang” nice and soft and move around loosely as it once did when to flacid. penis is now retreated /retracted as if in cold water, its almost withdrawn and seems it is lacking circulation/blood flow. penis once hung lower than the bottom of my testicles but is now actually pushed up and forward by how tight the testicles now are, and how reduced the size of flacid state is.

i found another person who experienced similar side effects to me. he stated he experienced:
– penile/scrotum shrinkage, loss of length/girth
– loss of morning/spontaneous/nocturnal erections
– empty/wrinkly scrotum
– penis constantly retreating as if in a cold pool
– loss of sensation/numbness to both penis shaft and scrotum, both feel lifeless/not pleasureable
– penile tissue changes: narrowing, curvature, darkening, emergence of numerous varicose veins along shaft

now i have not experienced the severity of his symptons, or his loss of size during erections, but it is quite alarming there are others out there who have experienced this issue and there isnt any warnings out there regarding this alarming side effect

after reading through several links below, one must question – is it possible that lack of DHT leads to decreased AR expression in penile tissues & nitric oxide production… leading to tissue changes, ie fibrosis/collagen deposition which cause such shortening/lack of bloodflow???

the links:
http://finasteride.jconserv.net/viewtopic.php?t=146
http://www.asiaandro.com/1008-682X/5/33.htm
http://finasteride.jconserv.net/viewtopic.php?t=346

thanks for any input you can share on this topic!

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DHT is very important in the first trimester of pregnancy when the testicles and penis form. If DHT is not present (mother on finasteride or born with a defect where the fetus does not make DHT), then a hermaphrodite will probably develop. For more on hermaphrodites, see:

It is true that being exposed to DHT blockers before puberty can negatively affect the development of the male external genital system and other secondary male sex characteristics (beard and body hair even after puberty). DHT is essential for development and growth of the male genital system before they are completely mature and reach their final size. Our current understanding is that the use of finasteride after puberty when the amount of testosterone is very high with corresponding high DHT levels, should not impact these secondary sex characteristics and will still allow the penis and testicles to reach their maximum size. There is not much information on the use of this drug in young teenagers and I suspect that prior to the age of 16 when balding may start in a select number of boys, the decision to use finasteride is easier the further into the teens the person is.

You have referred to a study done on 3 groups of young rats. This study has shown that a lack of either testosterone or DHT can affect the growth and development of the external genital system negatively.

In the studies done on humans, there was no report of similar or any other negative changes on the external genitalia in adult men or boys in their late teens. I have been recommending and prescribing Propecia to a good portion of my patients, and as of yet have not heard any such complaints with regard to impact on penis size once the penis has grown to its final adult size. You have to remember that this medication has passed all clinical phases and was proven effective and safe for treatment of male pattern baldness (in adult males). If you are still concerned with the changes in your genitalia, you can see a urologist to make sure you don’t have any other medical problems that have been causing this issue.

Hair Loss InformationDo Spicy Foods Really Put Hair on Your Chest? – Hair Loss Information – Balding Blog

This might sound like a joke, but something I’ve always been curious about. Does eating spicy foods really put hair on your chest? If not, I’m curious as to where a phrase like that would come from. You can laugh if you’d like. I feel foolish for even asking.

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Spicy foodI did a Google search for the phrase “put hair on your chest” and found that this idiom is use in many situations and many cultures. I really do not know the answer about where the phrase came from, but I did enjoy the threads as I searched for an answer. I hope you know that if anything really put hair on the chest, then it would be marketed as a cure for hair loss in some circles.

Somewhat related, here’s a list of other “hair” related idioms, from TheFreeDictionary.com.

DHT and High Cholesterol – Hair Loss Information – Balding Blog

I am a 36-year-old male noticing some hair loss. I thought it was related to having taken prohormones, but the slow hair loss has continued after more than a year off the prohormones. I am considering taking Avodart/dutasteride, but not just for the cosmetic hair loss. A concern I have is the relation between MPB to increased risk of heart disease. Thus, my two questions:

  1. Do you know of any connection between DHT and high cholesterol/heart disease? And if there is a connection, would DHT suppression also contribute a health benefit above and beyond the cosmetic issue of MPB?
  2. Do you have any suggestions for any OTC or prescription drugs/remedies that would work to help curb the aromatization of the increased testosterone from taking a DHT inhibitor?

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  1. I do not believe that using DHT blockers like Propecia will have any effect on your cholesterol. We know that Propecia will reduce the risk of prostate cancer.
  2. With regard to your second question, I am not an expert on OTC medications that curb aromatization from increased testosterone.

Subcapsular Orchiectomy (Removing the Testicles) to Prevent Hair Loss – Hair Loss Information – Balding Blog

Hello Doctor,
I am soon to be 25 yrs old. My hair line is beginning to recede at my temples. I am extremely concerned with this. For many years I have considered having a subcapsular orchidectomy procedure to prevent any further hair loss. I have researched the side effects of this procedure and am willing to accept them. Can you recommend a doctor who will perform this outpatient operation? Thank you for your time.

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Any urologist should be able to help you, but I doubt they would do so. There is likely more to your story than you are telling me here. Taking out your testicles is an extremely radical way to prevent further hair loss… though it will work.

Search Results for “procede” – WRassman,M.D. BaldingBlog

I am not a chemist, and I really cannot comment on if those ingredients will grow hair. I’m not seeing anything proven to grow hair in there, though. I can tell you there is no cure for hair loss. Even the best medications we have (Propecia and Rogaine) still have limitations. As the ingredients you […]

Why Does Society Put Such Emphasis on Hair? – Hair Loss Information – Balding Blog

I am 24 years old and I have somewhat serious hairloss. I have a receding hairline and thinning on top. My hair is so weak, that if I were to pull at it and brush my hand through my hair, there would be a large number of follicles in my hand. I took Propecia from the age of 21-23, but stopped when I turned 24. Going bald seemed inevitable, and at 24, I couldn’t stand the thought of taking Propecia the rest of my life. Every hair transplant I have ever seen always looks “unsightly” and often worse when compared to them bald. Why does society put such an emphasis on hair and is there any data that shows financial success with copious amounts of hair?

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LionYou could come to one of our free Open House events and see if your comment, “Every hair transplant I have ever seen always looks ‘unsightly’ and often worse when compared to them bald”, still holds true. I would challenge you to spot a hair transplant in many of my patients from what a normal non-balding man has.

You sound angry with your situation. Upon finding out what I did for a living, a woman at a dinner engagement last week said, “What is the problem with being bald anyway? I think that bald men are sexy.” I responded simply by saying, “If you take the lion’s mane away from the lion, you have a lioness.” You see, it is really a matter of perception. If a man feels less manly because of his balding, then hair is important to him. In particular, young men hang their image on anything that differentiates them from others. Balding at 23 years old certainly makes them different and that is not what they want. Generally speaking, women (particularly young women) don’t want a man to look older, and balding men tend to look older so that the discrimination is significant. I have found many wives bring their husbands for a hair transplant, because they do not want to have an older-looking man for a husband, particularly when they appear young or have had some plastic surgery to make them appear young.

I personally think that many men look great bald, particularly when the balding is in its final stages, but as they get there, some look scruffy and that becomes the motivator for hair transplant surgery. Clearly, a good hair transplant should not be visible and very few of my patients comment that their transplants were recognized as such. Examples of our fine work can be found at NHI Patient Photos.

What Questions Should I Ask When I Get My Miniaturization Test? – Hair Loss Information by Dr. William Rassman

Doc,

Thanks for this gem of a site! I’m scheduling my first miniaturization with the Hair Club for Men. Two questions:

  1. What questions should I ask the physician when we meet?
  2. Have you heard anything from your colleagues in the hair transplant world re: Hair Club for Men’s experience and success in restoring hair?

Thanks for your time!

  1. First and foremost, you should educate yourself on hair transplant surgery and hair loss. Just as you have found this site, you can find tons of information on the rest of the web. Just double check sources and make sure the information is credible. You can also use NewHair.com for extensive medical information on hair transplantation and hair loss.
  2. With respect to the reputation / success of other medical groups, it would be unprofessional of me to comment (positive or negative) on the matter since it would obviously be a conflict of interest. We have many suggestions in this blog on how to qualify doctors and you should follow that advice.

You need to know what the mapping of your miniaturization shows and you should ask the doctor what he/she might predict will be the eventual loss of hair (distribution/pattern) and the rate at which you might bald. If you are using medications like Propecia, you should be able to compare the progress or reversal of the miniaturization over a time period of months.

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Can Hair Be Transplanted Into Grafted Skin After Burn? – Hair Loss Information by Dr. William Rassman

Ten years ago my leg caught on fire and i got graft skin over the burn. know i got bald leg and hairy leg i wanna know if you can grow hair over the graft skin and get rid of the brownish color on it. thnk u

Yes, but it depends on the skin. I would need to see the quality of the skin below the grafted area to determine if transplanted hair would grow.

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