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The pathomechanism for omeprazole-induced hypertrichosis is not known. Omeprazole significantly increases duodenal prostaglandin (PG)E2 synthesis and elevates the expression levels of cyclooxygenase-2 protein and PGE2. Prostaglandin F2 alpha analogues, such as latanoprost, can increase pigmentation, thickness, length, and number of eyelashes. Prostaglandins are involved in hair growth regulation; PGE2 and PGF2 alpha stimulate hair growth, whereas PGD2 has an inhibitory effect. It has been suggested that a balance between PGE2 and PGD2 controls hair growth in mouse and human skin, whereas drugs that stimulate hair growth may exert their effects by acting on prostaglandin pathways. It has been suggested that minoxidil increases production of PGE2, and topical cetirizine, which has been reported to be beneficial in androgenetic alopecia, decreasing inflammatory cell infiltrate and PGD2 production. Prostaglandins may have an action on hair growth regulation through their vasomotor effects in the dermis, inducing blood flow in the perifollicular vessels, and by inducing DNA replication and stimulation of cell division and growth.

There is a solution in this disease because vellus hairs are turned into real terminal hairs. Can it be identified?

This is a review of a SMP procedure performed at New Hair Institute Medical Group. This is a female patient who had traction alopecia from wearing her hair pulled back too tight. She also had a component of triangle alopecia. SMP diminished the contrast between skin and hair. Note: patient also colored her hair on the after photo.

SMP to traction alopecia

This patient was treated with 0.1% dutasteride injections for 6 months. This is not an approved medication with regard to safety, so I am not rushing to start offering these treatments.

The following report came from the Alzheimer’s Association International Conference (AAIC) 2014 by Medscape Medical News: “A Simple Eye Tests to Detect Alzheimer’s Disease in the Works”

COPENHAGEN, Denmark — Two novel, noninvasive, and relatively simple eye tests show promise as potential screening tools for early Alzheimer’s disease (AD).

“Preliminary results from 2 studies presented here at the Alzheimer’s Association International Conference (AAIC) 2014 show that beta-amyloid detected in the eyes significantly correlated with the burden of beta-amyloid in the brain, allowing investigators to accurately identify individuals with AD

In the first study, researchers at the Commonwealth Scientific and Industrial Research Organization (CSIRO), Australia’s national science agency, used curcumin fluorescence imaging to highlight beta-amyloid in the retina and correlated these results using Pittsburgh compound B (PiB) positron emission tomography (PET) imaging findings in the brain.

“Every single person who tested positive with high levels of plaque in the brain tested positive to the retinal test as well, so we had 100% sensitivity and no false negatives, which is a crucial component on a screen for Alzheimer’s disease because we don’t want to leave anyone behind when it comes to the early signs,” lead investigator Sean Frost said at a press briefing here.

This is a very important medical breakthrough as Alzheimer’s disease (AD) will impact tens of millions of Americans in the future, possibly your own family. There are strong suggestions that changes in lifestyle (diet, regular daily exercises, no smoking) can reduce the timing of these changes and possibly reduce the incidence of this disease in the tens of millions of people who are highly likely to get it.

The best treatment for scalp scars is Scalp MicroPigmentation. I have extensively published on this technique and on the website you can see many examples of patients who had this done for scars of all types. Below is a typical example of a patient who had a scalp scar treated with Scalp Micropigmentation and you can see more examples of this here: https://scalpmicropigmentation.com/scar-covering/

Men under the age of 25 have a better chance of getting these type of results. The younger you are, the better the chances.

I’m so happy! (Fin is working) from tressless

Doctor can this happen on propecia. Ive been on it for 2 and half years with good results, maintained and thickened a bit, but my hair is weird. the first year on propecia it looked like it was getting worse, then into the second it started getting better over all. then again half way through the secong it looked bad again, and then a few months later it thickened again. I take pics, and that’s how I can tell. also there is a single hair that I excluded from the other hairs to follow and look at to see how it progresses, and to give me an overall picture on how the other hairs might be responding and growing. the last month or so that specific hair thinned and looked like it was gone, and then a few days a go I see It growing and thickening again. I know this is a weird email lol, but from you experiences does hair go through diff stages?

To be exact I started propecia in june 2013. from june 2013 to june 2014, it looked like I lost ground a bit, so I still stuck it with propecia. then around January 2013 my hair started looking good, and was thicker and the pics I took started to show a difference from the baseline. around april of 2013 my hair looked thin again and looked like I was reverting back to baseline. around august till about now my hair has looked its best. I started noticing new hairs sprout from the hairline that were not there before, and the looked so much thicker, and way different from baseline. its basically at its best. my question is why does it go through these stages? bad, good, bad, good, etc? is that normal?

Our hair will cycle and grow in different stages, so some hairs fall out while others grow from a stem cell that regenerates the hair follicle. You may be noticing some changes, but you cannot really say with scientific objective certainty what is really happening with just subjective observations or pictures. For example, dry frizzy hair in dry fall weather can make your hair seem voluminous, where oily damp hair in the humid summer days can make your hair seem flat and thin. Even different shampoos or hair products can affect how your hair may look and feel. For a more accurate analysis, we try to quantify it with measurements such as a miniaturization study and hair bulk measurements and compare the values on a yearly basis.

Finally, you need to understand that being on Propecia does not mean your hair loss will stop. Based on your genetic predisposition you will continue to lose your hair to the predestined hair loss pattern. Taking the medication (Propecia) means it will probably slow the process of hair loss down but each individual’s response to the drug is different. There may be some variations where you may notice less hair loss and more hair loss over the many months to years. We generally lose about 100 hairs a day (on the average), but this number is also highly variable with time for the individual. So I think what you are experiencing is likely normal.

Simply put, what you see may not reflect what is really happening. That is why we measure hair bulk with the HAIRCHECK instrument and also a microscope for a Miniaturization Study. The metric (numbers) what they instrument tells us, will allow us to compare a year ago to today and determine if you are really losing hair or not.