Does maturing hairlines happen because of a males testosterone?

I don’t know for sure but I suspect that you are correct. We know that females generally do not get the receded mature ‘male hairlines’ that men do. Could this be caused by genes related to our sex alone or is it that two X chromosomes with the high estrogen levels in females protected against the mature hairlines. No one has been able to study this. These hairs in the zone between the juvenile and mature hairline certainly have an ingrained number of hair cycles which then produce ‘apoptosis’ (cell death) of these hair cells possibly triggered by testosterne,

Are You Sure Minoxidil Doesn’t Block DHT?

You’ve stated on your website that minoxidil doesn’t block DHT. How do you know this? Perhaps this is the mechanism by which it regrows hair. I’ve tried finasteride and dutasteride with virtually no results. While my result with minoxidil hasn’t been spectacular, it has definitely been superior to the other two drugs.

Minoxidil has a known side effect, in that it will grow hair when it is taken orally or applied to the skin. Women complained of the appearance of facial and chest hair when this drug was used as an antihypertensive drug. I can’t state with 100% certainty that it doesn’t block DHT, but that is not what is reported. What has been reported is that minoxidil is a vasodilator, not a DHT inhibitor.


2010-03-09 08:59:23Are You Sure Minoxidil Doesn’t Block DHT?

Medscape and Dr. F. Perry Wilson questions the value of stems cell treatments and relates it to doctors making money

Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I’m Dr F. Perry Wilson.

I want to start with a compelling narrative being told to patients across the country. It goes like this: We physicians are going to use cutting-edge science to unlock the healing potential of your own cells to treat your chronic medical conditions. Sounds amazing, right? And it can all be yours for just about $5000 per treatment.

I’m talking about stem cell therapy. Stem cells are cells with the potential to differentiate into a variety of other cells or tissues. And to date, the FDA has approved their use in a number of hematologic malignancies and hematologic genetic conditions—and that’s it.

Stem cells are not FDA-approved for joint pain, cataracts, depression, autism, dementia, or heart disease, and yet hundreds of stem cell clinics around the country are offering them for these very conditions, as shown in this study appearing in Stem Cell Reports,[1] which documented the activities of 169 stem cell businesses in the United States.

These for-profit companies charge patients thousands of dollars for unproven treatments. Patients bear the brunt of the costs, as most insurance companies won’t cover the therapies.

Up until recently, this was basically unregulated, though the FDA has started to change that.

The Stem Cell Reports study characterized 169 stem cell clinics in the Southwestern United States to systematically measure just what they are selling and who is running them.

As you can see here, the range of conditions being treated is incredibly broad, with inflammatory and orthopedic conditions topping the list.

From Frow EK, et al. Stem Cell Reports. 2019;13:1-7.

Who’s running these places? The majority are run by MDs, though there is a smattering of other providers, as you can see here.

From Frow EK, et al. Stem Cell Reports. 2019;13:1-7.

What raises my hackles a bit are the clinics where the training of the provider doesn’t match up with the services offered. It’s one thing for an orthopedic surgeon to offer stem cell injections into arthritic knees, but the authors documented clinics run by cosmetic surgeons offering treatment for lung disease and autism.

Are these clinicians providing cutting-edge treatments or is it a shameless cash grab? Maybe both? These treatments are not entirely benign. In 2017, several patients went blindafter their own adipose-derived stem cells were injected into their eyes. Infection remains a risk as well, as the cells are removed from the body, processed, and reinjected.

There is a reason that we demand well-conducted, randomized clinical trials before we embrace new therapies. In no small part, it’s to ensure that we are abiding by our Hippocratic Oath to first do no harm. Can these providers honestly say that they are meeting that standard? Look, I’m not saying that stem cell therapies are modern-day snake oil. They really may work. But we don’t know if they work and we don’t fully understand the risks. Why are certain individuals — MDs — willing to expose patients to risks they don’t fully understand?

Well, I can think of about 5000 reasons.


2019-08-08 07:38:59Medscape and Dr. F. Perry Wilson questions the value of stems cell treatments and relates it to doctors making money

Do men or women lose more hair per day naturally

Men actually shed more hairs per day because they have a shorter anagen cycle. Women can grow their hair much longer than men so they lose less per day and regrow less as well. Women can grow hair as long as 3 1/2 feet while men can’t and often grow their length to no more than 18 inches in length. That means that using the formula of 100,000 hair on the head for a typical Caucasian, if the hair is shed after anagen, the women with 3 1/2 feet length hair will lose about 50 hairs per day while the male who will grow to a length of 1 1/2 inches will lose up to 100 hairs per day.


2019-03-22 07:59:18Do men or women lose more hair per day naturally

I Have Asymmetrical Receding Hairline

I share this because I think Im a pretty good example of aysmmetircal receding of the hairline. I am a 27 year old (half Italian half English caucasian male) and my right corner of my hairline began to slowly recede exactly two years ago.

The left is still more or less compltely in tact ( I know it will catch up in time)

My father is 49 and he has the same hairline as this guy images (but short hair not long)

No hair loss at the crown (or negligible) and heavily receded hairline, but overall a decent amount for a near 50 year old. It is thinning more the last few years though. I think he said he started balding at 27.

His father has slightly more hair than him, basically a near full head of hair at 75. My mother´s father has a Norwood at 75. There are no complete baldies in my family.

I guess I would like this to be a ‘mature’ hairline but Im not sure that exists anywhere other than in moviestars and this will continue to receded.

As I said, my left side is totally fine, my right side has receded an inch or so and in that space where the hairline was is some minituarisewd hair. Behind it the hair appears fine and not miniturarised. Very thick hair overall.

Thoughts?

It’s quite simple. We are all built differently! In fact we are not quite symmetrical as you may think. Some have uneven length arms, uneven shoe sizes, uneven smiles, etc. Hair line and recession is not immune to such asymmetry. On a positive note (if you want to call it positive) the other side will likely catch up with the receding side with time.

Microblading gone wrong

I had my eyebrows microbladed six months ago and the results are horrendous. How do I get rid of this ugly look quickly?

There are laser that are very superficial like the Q Switch laser that could take out the inks. There is a risk that you might lose your eyebrows if the inks were placed deep in which case you might then need an eyebrow transplant.


2020-11-05 12:48:35Microblading gone wrong

Avodart and Androgenic Alopecia in Women

What information did you learn about Avodart’s effectiveness in treating androgenic alopecia at the Sept. ’05 conference in Sydney, Aust.? Any hope for female pattern hair loss?

Avodart (dutasteride) may have value in those men where Propecia (finasteride) fails to work, but as it is not FDA approved for treating hair loss I can not in good conscience wholeheartedly endorse it. It does not show value in women.

Microneedling does bleed

This is a good photo after microneedling that goes down to a depth of between 1 – 1.5mm. This is where the stem cells are targeted. There is going to be some pain but most men who do this once a week put up with the pain for the gain.

Bad side effect reported with Minoxidil

I want to say that, I used Rogaine a month ago. I applied it only 3 times, mainly due to the headaches, heart palpitations and dizziness. Since stopping I have had hair coming out like crazy. People at work have noticed and I’ve noticed dark circles under my eyes and a puffy face. Stay away from this product. I’m just hoping the hair that I have lost since using it comes back.

This is highly unusual and must like is the result of a combination of some allergy plus significant drug absorption over time.