Why Do Men Want to Switch from Finasteride to Dutasteride?

Many men think that Dutasteride is better than Fnasteride. Finasteride is 70% effective as a competitive inhibitor while dutasteride is about 80% as effective. However, most people don’t really see the difference from a practical point of view. The drug Dutasteride is not FDA cleared. Therefore, it is not proven to be safe. We know, for example, that Dutasteride produces sterility in some men.


2018-07-18 12:26:30Why Do Men Want to Switch from Finasteride to Dutasteride?

Astressin-B

Does anyone think the new drug called astressin-B has any possible benefits to regrow hair? I am surprised no one has asked any question about the new finding made last month. Researchers claim that mice grew hair when injected with the drug astressin-B, how far is this true and how long would it take for the treatment to be available.

Thanks

Actually, we did write about this last month.

Quick recap — researchers discovered that a compound (astressin-B) that blocks the action of a stress hormone called corticotrophin-releasing factor (CRF) was able to regrow hair in genetically altered mice. There isn’t enough information available to discuss anything beyond what was published. It is all hopeful, but the FDA process will take years before safety and effectiveness is proven in humans.

Micro needling redness

when i microneedle i achieve redness all over the scalp, but within the hour the redness goes away and by the morning it’s completely gone and i feel no pain at all. am i doing it wrong? is there no inflammation?

Some people have Histamine positive skin which turns red easily. If you scratch your forehead with your finger nail and it turns red in a few minutes, then you have Histamine positive skin. It just takes longer to lose the red color. Microneedling is becoming more and more popular to bring back the hair from the micro-wounds it creates. It does work on some people


2020-07-27 15:21:50Micro needling redness

Average Age of Developing MPB?

What would you say the average age is for men to develop MPB? I know there is a wide window, but what is considered to be the norm? (Any pattern of MPB)

Most people lose (or start to lose) their hair in their 20s. A few people have started it as early as 14, but that is unusual. I have seen others start losing their hair into their 50s or 60s.

Microneedling before and after (photo)

The use of 1 or 1.5mm needle length will produce bleeding. Healing is slow and if you repeat this every week, the pink color may persist over the entire week depending upon your skin characteristics. Be prepared to have a pink color show here after the microneedling has healed a few days.

Bad Hair Transplant Results (photos)

The arrows show large grafts at the hairline, something that should never be done as they appear pluggy. Also growth seemed either under transplanted or this man has inadequate growth. Either way, this man should get his money back and go to a good hair transplant surgeon to fix the problem


Microneedling plus topical minoxidil and finasteride spray (photos)

That is a very impressive result. The microneedling was the key here; once a week, the 1.5mm needles helped it along nicely. The long-term becomes an issue; in other words, what must you do to maintain your final result when you get there? I am almost sure that if you don’t maintain some microneedling, even every month, these hairs, when they go through their next cycle, may not go into anagen (the growth phase) without the stimulus of the micro-needling. This could happen even earlier than the next hair cycle. We just don’t have the information we need to answer that question. You would find out the answer to that question if you did follow-up repeating the microneedling. If the hair starts falling out again, pick up the microneeding and write to me.

Bald Scalp, Greasy Forehead?

I have noticed that 90-95 of men who are losing their hair have a greasy or shiny forehead or scalp including myself. But what I also noticed is that men who have excellent hair never ever have a greasy or shiny forehead or scalp. I feel if we can control what is ever producing that greasiness then we can control hair loss. What are your thought or have you read or head about any research in regards to this?

I am not convinced that greasy hair is related to hair loss. If you have hair you would not notice their greasy scalp from visual observation alone (as the hair is covering it)

Male pattern balding is related to genetics. Greasy and oily skin may also be a genetic issue, but not related to the hair loss gene.


2012-09-24 10:46:03Bald Scalp, Greasy Forehead?

Balding 22 Year Old Woman (with Photos)

This 22 year old patient came to see me for hair loss she’s been experiencing for the past 2 years. She did all of the right things, saw two dermatologists, and received a complete medical work-up for a variety of disease entities and vitamin deficiencies and was found to be normal. What I told her is as follows:

  1. Obtain a new test for androgen sensitivity of her hair based upon a genetic test
  2. If she is sensitive to androgen, we might try her on an androgen blocker such as finasteride or dutasteride in the hope that this will block enough of the androgen to allow better hair growth.

The science is minimal that support this thesis, but it is better to try to block the androgens on women who are positive to the genetic test for androgen sensitivity than to put all women on the drugs.

In addition, as we could not offer her an immediate benefit with drugs, we used a concealer treatment on her hair and showed her how to do this herself. Her comment after the application of DermMatch was, “I have been reborn”.

I apologize for the blurriness of the before photo. Click the photos below to enlarge. Before (left); After (right)