Children mistakenly given oral minoxidil in place of stomach ailment drug
https://www.yahoo.com/news/spanish-parents-demand-compensation-children-153113188.html
2020-12-07 02:37:152020-12-03 10:39:33children got minoxidil by mistake
One side of my hairline is much more receded than the other
Male pattern balding with recession is often asymmetrical. The side that is behind will often catch up with the more receded side.
I have a Class 6 pattern of balding, can we discuss the math?
This is my math: 6000 donor follicles available. Average head has 100000 hairs. Can lose 50% of hair density before it’s visible. Say a norwood 6 loses 60% of their hair (40% left on sides) that’s 60000 hairs. Need 30000 hairs replaced to reach 50% density and look like a full head. Average graft 2 hairs. 15000 grafts = 30000 hairs would look like a full head. Could sides be over harvested from 6000 to 10000 to replace 20000 hairs? 2/3 of full apperance. Sides clipped to no1 with SMP to cover overharvest?
Answer: ?Your math is partly right. The donor area is always determined on the Class 7 scale not the Class 6 scale, which essentially reduces the donor area to about 20,000 hairs or 10,000 grafts, which can be harvested at say 60% assuming that you have an average donor density. Graft numbers are adjusted according to hair weight (coarse vs fine), color and contract between hair and scalp and hair character. The artistic judgment of the surgeon manages the multi-variant analysis as everything is not by the numbers alone.
Oorey Lanez hair transplant looks great (from Reddit)
2018-11-06 07:36:022018-11-05 07:36:57Oorey Lanez hair transplant looks great (from Reddit)
Cloning hair cells
https://www.sandiegouniontribune.com/business/biotech/sdut-hair-stem-cells-papillae-gnedeva-terskikh-burnham-2015jan26-story.html
This has been done before. I remember attending a lecture which described these cells put into mice and since the direction couldn’t be controlled, the mice all died from ingrown hair infections
Orchiectomy and Hair Loss
Hello Dr. Rassman,
First off, thank you for your excellent blog, extremely informative!
I am a 37 year old male who has had an orchiectomy (right testicle), which occurred about 1 month ago. So far everything is working out well (aside from fatigue) and I have not had any testosterone replacement therapy at this time. I also have some hair loss, I’d say I am about an early Norwood 3, with no loss at the crown (yet).
My question is this: What can I expect in the way of hair loss at this point? I realize my testosterone levels are lower (503ng/dl), and I’ve taken 1.25 mg of Proscar daily for about 6 months and it seems to have worked quite nicely, but I am still wondering what impact the orchiectomy might have for my hair loss. Will my hair loss advance as rapidly as it would have had the orchiectomy not occurred, or will it possibly stop?
Thanks Doc!
A loss of one testicle will be compensated by the other testicle as it may “rise” to meet the needs of your body. Usually, the remaining testicle will increase testosterone production and this is something you can follow with your doctor through appropriate blood tests. There should be no impact on your hair loss other than what you were destined to lose based upon your genetics.
Does combining finasteride and minoxidil work?
Combining finasteride and minoxidil is a good idea. You should get a HAIRCHECK instrument test to find out exactly what hair you are losing and how these drugs reverse the process. IF you are in Southern California, my first visit for this test is free
over-harvested donor area (photo)
Another photo of a man who had FUE and as a result had an over-harvested donor area. The donor area that was harvested was larger than the permanent zone so some of the transplanted hairs will not be permanent and may fall out in time. This depleted donor area could be treated with scalp micropigmentation
2020-09-19 06:41:512020-09-20 09:32:15over-harvested donor area (photo)
Comparison Between Finasteride and Dutasteride
Note: Article Warns of Variations in the Quality of These Drugs on the Market
Pharmacogenetic analysis of human steroid 5 alpha reductase type II: comparison of finasteride and dutasteride
Human steroid 5 alpha-reductase type II is a prostate-specific, membrane-associated enzyme that catalyzes the conversion of testosterone to dihydrotestosterone, the most potent androgen in the prostate gland. Genetic variants of this enzyme have been associated with both the development and the progression of prostate cancer. Both finasteride and dutasteride are competitive inhibitors of the type II steroid 5 alpha-reductase that have been effectively used for the treatment of benign prostatic hyperplasia. Finasteride has also been successfully utilized for prostate cancer chemoprevention. We here investigate 5 alpha-reductase inhibition assays in vitro to measure the effect of incubation time on the apparent inhibition constant (Ki) for both constitutional and somatic (prostate cancer) enzyme variants. Our systematic pharmacogenetic analysis shows that both finasteride and dutasteride are slow, time-dependent inhibitors of steroid 5 alpha-reductase type II, and that the inhibition kinetics depend on the 5 alpha-reductase genotype. We also show that, overall, dutasteride is a more efficient steroid 5 alpha-reductase inhibitor than finasteride. Based on our data, we are able to map areas of the enzyme that are responsible for this time-dependent inhibition for either (or both) enzyme inhibitor(s). This comprehensive pharmacogenetic analysis of steroid 5 alpha-reductase variants unveiled significant pharmacogenetic variation for both finasteride and dutasteride and thus should be taken into account when designing protocols for treatment and/or chemoprevention of prostatic diseases with either one of these 5 alpha-reductase inhibitors since there is considerable pharmacogenetic variation for both drugs.
2020-02-20 04:00:362020-02-22 12:20:03Comparison Between Finasteride and Dutasteride
Hair Loss InformationFemale Hair Thinning – Hair Loss Information – Balding Blog
Hello sir,
I am an Asian female and I am 24 years old.About 3 years ago, I noticed that my hair had started thinning. That was a period of time when I was under a lot of stress and used to hav a bad diet as well. So I thougt that was the reason for my hairloss and also thought it would come back in time. I have lost hair mostly from the front region of my head.But am not loosing much hair now.My hairloss kind of reduced on its own about few months ago and I also see few hair coming.So does that mean that I am gonna get back my lost hair? Was the damage irreparable? Should I take treatement?
My mom had lost a lot of hair at a young age,my dad is 60 years old ,but still not bald. Could you please let me know more about my hairloss and whether it will come bacK or not.I would be extremely grateful sir.I am undergoing a lot of pain because of my hair.
You are not alone. Since I started this blog, I have gotten quite a few questions from women about their hair loss problems. Here is a link to the similar questions and answers. The first thing you need to do is to see a physician who can examine you and order tests to make sure that there are no underlying medical reasons for your hair loss. Some of the reasons for female hair loss are: anemia, thyroid disease, connective tissue disease, and various gynecological conditions. These laboratory tests may be useful if underlying medical problems are suspected: CBC, Chem Screen, ANA, T4, TSH, STS, Androstenedione, DHEA-Sulfate, Total and Free Testosterone.
If it is determined that there are no medical reasons for your hair loss, I would suggest that you visit a hair loss specialist. Since you are in New Jersey, I can highly recommend Dr. Robert Bernstein in Fort Lee- his phone number is 866-576-2400.