Histogen HSC Trial Results Published Late 2011

Hey guys. Histogen published an article about it’s HSC in the Journal of Drugs and Dermatology several months ago, of which I’m sure you are aware. Are there any thoughts about this article? or about the Journal?

Link: Hair regrowth following a Wnt- and follistatin containing treatment

Sounds interesting. It was published in the Journal of Drugs in Dermatology, which is a peer-reviewed publication that has been around for a little over a decade.

As for the study — this looks like it might’ve been a pilot study, and consists of only 26 participants. Clinical application and mainstream treatment remain to be seen.

Histamine Positive Skin and Hair Transplantation

Hi,
I would first like to thank you for this very informative site. My question has to do with post operational side effects. Specifically, I had FUE/FUT 1.5 months ago. Unfortunately I have something my doctor called histamine positive skin. As a result there is redness in the recipient area. My first question is related to that.

How long would it take for such redness to fade away and what can I do to reduce that amount of time? Additionally, in the donor area, there is a significant amount of redness and the hair growth appears limited. Is this to be expected? And what is the time frame for full recovery of the donor area? My doctor is quick to say it will all be fine in a few months but I wanted a second opinion as well as anything I should keep an eye on to better facilitate the recovery of that area.

This was my first surgery and I only had 1000 grafts transplanted.

If your doctor was helpful enough to explain a histamine reaction to you, how is it possible that you were not told how long it would last? I often do a scratch test to the scalp or forehead to preselect those patients who are histamine positive. In general, every patient is different and the redness can last several weeks to months. 1 to 2 months would seem on the long side.

Unfortunately this is not a place for second opinions as I do not know what you are really experiencing. All hair transplants are not the same, especially FUE, as there are many variables such as size of punch, techniques of extraction, the drugs you take, the allergies you have, etc, etc.

Hirsute Men and Head Hair Loss

As a writer focusing on men’s health issues I would be interested in your comments on two areas of my research.

  1. I have read a number of reports that suggest that hirsute men (those with a lot of body hair on chest, shoulders etc) are more prone to lose hair from their heads.
  2. I have also seen reports that the American Red Indian does not suffer from hair loss.

I do not believe these issues have been dealt with by you before.

I too have seen claims that men with heavy populations of body hair have more balding than their hairless or less hairy counterparts. I can say that in my medical practice, the balding men routinely say: “I wish you can take it from my chest or back”. But then again, I do not have the type of interchange with non-balding men to probe the same issue. There is generally a belief that DHT (the evil hormone that ‘causes’ hair loss), also brings on the body hair, the nose hair and the ear hair along with the balding on those genetically inclined balding men. I believe that in the discovery of Finasteride, the people who ingested large amounts of this drug through their dietary intake of a food stock from the rain forest, did not bald, nor do the men born with a genetic defect where they can not make the enzyme that produces DHT. I recently probed a large number of doctors asking if anyone has found evidence of a reduction of body hair, nose or ear hair with Propecia. Everyone liked the question and told me that although they believed it might just do that, there is no evidence that Propecia or Proscar actually blocks or reverses these less than ideal hair locations.

With regard to the American Red Indian, I am fully aware of this observation. His ancestors came from the Alaskan bridge and they had the balding trait, so it is strange that this particular ‘race’ (the great grandchildren of the migrating Alaskan ancestors) is unique amongst all humans as they do not have balding. Of interest, I am not aware that these people are missing any enzymes for making DHT. Could it be that a primitive people actually wiped out balding genes in their brothers in a relatively short time frame of less than a couple of thousand years?

Higher Strength Minoxidil

I got a prescription for Avodart here in the states.I will start today.I have read on the internet that there is a 12.5% minoxidil lotion and a 15% minoxidil cream that are better than the 5% you can buy over the counter.I want to start a new hairloss program but i want to make sure that im doing the best possible treatment for my hair.Are these stronger creams better or should i use the over the counter 5%.I have been depressed but i can not give up on my hairloss.Your input on this email will be very helpful!

You can try higher strength minoxidil, but just be wary of the drug’s side effects like dizziness or skin irritation. I have no particular experience with 15% minoxidil, but if you want to try it, I have not heard anyone saying it is bad.


2005-11-15 15:11:34Higher Strength Minoxidil

Higher Sex Drive from Finasteride Leading to Increased Masturbation

Dear Dr. Rassman,
I am taking finasteride for my hair and it’s working well on me. I am 23 years old. But my problem is i am having higher sex drive than before and also having increased number of masterbation. What can i do? My question is does increase in sex drive and thus increasing the number of masterbation affect the effectiveness of finasteride? If testosterone is increased by finasteride, does it affect the effectiveness of testosterone? My last question is people say masterbation is related with hair loss. If it were true then now in the world every healthy mature married men would be bald, isn’t it Dr.?

It is true that Propecia (finasteride 1mg) can cause an increase in your sex drive, but just as I always caution men who have a decrease in sex drive, do not be so quick to blame the drug. Young men in their early 20’s naturally have a high sex drive. It is normal to masturbate.

Does masturbation cause hair loss? No!!! Once again… masturbation does not cause hair loss! Your hair loss is likely caused by your genetics.


2008-10-03 11:38:16Higher Sex Drive from Finasteride Leading to Increased Masturbation

Higher libido, more hair loss on finasteride

Hi, I began fin 2 months ago and my hair is significantly worse. It’s really thinner and my hairline is more receded than before. Also, I’ve a lot more sex drive like never before. I dont know if it’s a shed or if fin is having the opposite effect on my body.

Stick to the finasteride and it should slow down the loss. You are one of the lucky guys that get’s an increase in libido with finasteride

High Stress or Bad Genetics?

Hi Dr. Rassman,

I’m 22 and I’ve begun the early stages of balding, no doubt about it. Nobody in my known family has begun balding as young as I have.

In the past 5 years, I have been through severe emotional trauma; watching my dad wither away and die from a rare form of cancer, dealing with my mom’s substance abuse problems and a suicide attempt from her, and struggling to live on my own. I have had severe depression and suicidal thoughts recurring.

My question to you is: is there any way this stress could have brought about the expression of my balding pattern younger than I would have if I had a healthier mental health record, or would bad luck in genetics be more likely to blame? Thank you in advance.

Stress related balding is different than genetic balding. Stress related balding is likely reversible. For genetic balding, there is no cure… but there are adjuncts such as medicine and surgery.

There is one catch: stress can precipitate genetic balding earlier on. BUT you have to have the genetic trait to bring this about.

Finally, while genetic balding is considered hereditary, it does not have to mean your immediate or distant family must have balding. In simpler words, the gene may have been ‘silent’ until it came to you.


2011-04-19 07:01:09High Stress or Bad Genetics?

High Side Hairline (Above Ears) — Can It Be Lowered?

hi there,
i’ve been reading some of these articles about high hairlines, and most of them talk about the hairline at the forehead. however, with me, my hairline at my forehead is fine, its the hairline at the side of my head (near my ears) thats high. its been a real issue with me ever since i was a kid and i’d always need long hair to cover it up so that it wouldn’t seem as if i’m balding (which i’m not). my doctor says that i am not vulnerable to balding when i get older. i am an 18 yr old filipino male. and i was wondering if there are any treatments to this surgically/nonsurgically. i’d prefer nonsurgical more than surgical. but if there is anything at all, pls tell me. thx

Some people have a genetic high temple hairline (above ears) which can be treated with hair transplants very effectively. There are no other treatments for this that I know of.

High prolactin levels while on finasteride

So I’ve been taking Finasteride for about 2.5 years with no problems at all and with very good results. However, I recently did a hormone check and my Prolactin was very high (almost double the normal range). Now while I feel fine and don’t have any of the symptoms of high prolactin would you recommend I stopped the fin? Is there a chance this could be causing my very high prolactin levels? Any help would be really appreciated as I am a bit worried about what the future may hold.

There is information that is difficult to integrate with a high prolactin level in men. We don’t know, for example, that this was caused by finasteride. You should see your doctor for clarification of the issues which gets confusing as you can see below.

This is what I found in the internet: Men — When a high blood prolactin concentration interferes with the function of the testicles, the production of testosterone (the main male sex hormone), and sperm production. … High levels of prolactin in the blood also cause difficulty in getting an erection, as well as breast tenderness and enlargement.

One common cause of hyperprolactinemia is a growth or tumor on the pituitary gland called a prolactinoma. The tumor produces high levels of prolactin. … Large tumors can also cause headaches, vision problems, or both. Prolactinomas are more common in women than in men and rarely occur in children

In Men — When a high blood prolactin concentration interferes with the function of the testicles, the production of testosterone (the main male sex hormone), and sperm production. Low testosterone causes decreased energy, sex drive, muscle mass and strength, and blood count (anemia).

That is why you need to see your doctor.

 


2020-07-16 08:13:09High prolactin levels while on finasteride