Dear Dr Rassman,
Have you had any patients who have taken very low doses of finasteride (i.e. less than 0.25mg)?
I am not keen to take propecia because I’m concerned of the effects to my internal body chemistry but would also love to keep my hair for longer. I have had issues with my sex drive previously and do not want to mess with my hormone balance too much as a man still in my 20’s. Another reason being that I’m an athlete and want to be at my peak physically. I’ve read a lot about how finasteride affects the hormones, particularly the obvious reduction in DHT but also the decrease in free (not total) testosterone and the rise in estrogen.
Then I read this forum post: Hairlosstalk.com
It seems that taking a dose as low as 0.05mg is enough to lower scalp DHT considerably while keeping 20% more DHT in the blood. Like the original poster in the forum thread who is considering crushing a pill and measuring smaller doses – this prospect is more appealing to me. If I could just lower my blood DHT by 40-50% instead of 70% then surely my hair would still get some benefit and I would be able to keep my hormones at a more normal level. I have ruled out taking 1mg but am really curious about taking 0.05mg if only I could just measure it accurately each time (I wouldn’t want to take fluctuating dosages each day).
It makes me wonder why propecia isn’t available at a much smaller dose (0.05mg or 0.1mg)
Could you comment please? I’d very much appreciate it. Thanks for such an informative blog.
Propecia (finasteride) at 1mg was determined to be the ideal dose for treating hair loss. Lower doses do work, but how low? I’ve said that 0.5mg produces 80% of the benefit, and 0.25mg probably give 50% of the benefit. I don’t have a clue about lower dosages.
But by dosing the 1mg level, it is the most effective treatment level to use… so why dose lower unless there are significant side effects?