2018-06-22 05:58:192018-06-22 06:48:45Was This Caused by Traction Alopecia?
What Is the Cause of Pitting and Cobblestoning, Which Is What I Have Since My Transplant of One Year Ago?
The cause of pitting is the placement of the grafts below the flat skin edge.
Cobblestoning occurs when the skin disc on the graft is too large and is often placed just above the skin surface.
These are technical details that result in catastrophic problems for the patient.
“Catch-up Hair Loss”
If you used finasteride for a year and it slowed or stopped your hair loss and then you stopped the drug, you would play ‘catch-up’ hair loss and could lose all of the hair you would have lost while you were on the drug.
Yes, if you used finasteride for a year and it slowed or stopped your hair loss and then you stopped the drug, you would play ‘catch-up’ hair loss and could lose all of the hair you would have lost while you were on the drug.
2019-10-09 05:06:302019-05-01 08:06:44“Catch-up Hair Loss”
Catch-Up Hair Loss, Finasteride, and Hair Cell Suicide
Hi, Dr. Rassman.
You’ve written a number of times about the “catch-up” loss that happens when a patient discontinues finasteride/propecia. I know you didn’t design the drug, but I was wondering if you know how this catch-up process works.
What I have a hard time understanding is this: If androgenic alopecia is a gradual process of miniaturization, why doesn’t that process-when you stop the drug-just pick up where it left off at the start of therapy? It seems like something must be getting worse “behind the scenes” during the course of therapy. Is it known what that something is?
I hope that made sense. Thanks!
Propecia (finasteride 1mg) sustains scalp hairs that are genetically susceptible to falling out. It does this by a process of competitive inhibition. When the drug is no longer available, the DHT is manufactured by the body and it ‘attacks’ the hair follicle which is like turning off the ‘life’ switch of the dermal papilla cells (which manufactures the hair follicles).
Once you stop taking the medication, you will not lose all the hair at once, but the ‘attack’ will occur over a few months. The hairs that were being supported by finasteride will go back to its pre-destined state, which is something called apoptosis (these dermal papilla cells that generate the hair follicle commit suicide — just die off).
For more about apoptosis, see ResearchApoptosis.com and Wikipedia.
2008-06-25 15:35:222008-06-25 09:32:23Catch-Up Hair Loss, Finasteride, and Hair Cell Suicide
Castration and Hair Regrowth
From what I have read, castration stops hair loss however, castration will not regrow hair that has been lost. If this is true, why would Proscar grow any hair? It is my understanding Proscar blocks a percentage of DHT, which leads to the effectiveness of the product. If someone has been castrated there is o% DHT and still no hair regrowth? Also if DHT causes hair loss why is Propecia effective on the vertex of the scalp and not the temples.
There is a wide audience of young men (over a million) who have taken Propecia and we know that in the very young man with active miniaturization, the process may be reversed. This occurs mostly in young men in their 20s. I would guess that if we castrated 1 million men who are balding in their 20s, that the incidence of regrowth would be higher than those on Propecia alone, but I am not recommending castration as this is only an intellectual exercise.
When a hair is dying (miniaturized hairs fall in this category), like a dying person, they have a chance of being fixed or cured because they are not dead yet. When a hair has completely disappeared, it has gone through apoptosis, which means that the hair growth center is dead… and we all know that you can’t raise the dead. This applies to hair when the head is slick bald in any area impacted where there is no miniaturized hairs.
2009-11-30 15:35:152009-11-19 16:17:51Castration and Hair Regrowth
Cassiopea, Another Drug for Balding Now Going Through Phase 2 Clinical Trials
We need alternatives to Finasteride, and this drug may be a good alternative if and when it completes clinical trials.
https://www.cassiopea.com/news-and-media/press-releases/yr-2018/180716.aspx
Carona Virus projects particles come out of our mouths
Just look at the distances. This is why it is important to keep away from other people if you want to avoid catching the Carona Virus. If you wear any protective mask and you have the virus, the mask will catch the projected droplets from your breath but the mask may not protect your from breathing it in when you are near someone who is projecting these droplets. The last photo shows microdroplets in a room 20 minutes after a cough by the person on the right. The entire room has circulating microdroplets exposing everyone in the room to potential infection. The last photo is from a video showing what happens in a super market where one shopper coughs and another is caught up in the droplets spread after a single cough in just seconds. In the stagnant air of an indoor market, virus particles spread very easily in the hair if someone is infected coughing.
2020-04-05 16:06:522020-04-09 19:51:04Carona Virus projects particles come out of our mouths
Why Can’t My Transplanted Frontal Area Have a Density Equal to What It Was Originally There in a Single Surgery?
The recipient area density is never equal to the original density, nor should it be because all of the donor hair would be used up. Also, there are mechanical limits on how closely a doctor can place the grafts to allow sufficient space and blood supply for good healing
2018-06-19 06:21:342018-06-21 06:17:35Why Can’t My Transplanted Frontal Area Have a Density Equal to What It Was Originally There in a Single Surgery?
Can’t Take Finasteride, Follow-Up
I want to reference: Can’t Take Finasteride, But Is a Hair Transplant Still an Option?
Dr Rassman,
Thank you for answering my original enquiry. Whilst i understand that one your goals is to protect patients from over enthusiasm for a HT. But is a HT something you would do on a 22yr old male who can’t take finestaride. I ask this before one fly’s across the globe to see you for a consultaion.
Thank You
I can not tell you for certain that I would do a hair transplant on you without knowing your donor density and doing a miniaturization study to determine (if possible) what your projected hair loss is. Knowing your supply and demand potential and your density and laxity, I would then make a decision on a hair transplant on you. So if you can’t or won’t take Propecia (finasteride 1mg), it does not 100% rule you out, but I first need to make that assessment.
We can arrange a call after I receive good photos of you and base some of this evaluation at the time of a telephone consultation. To setup the telephone consultation with my office, you can fill out our handy web form and you’ll be contacted via email to complete the setup.
Can’t Take Finasteride, But Is a Hair Transplant Still an Option?
Dr Rassman,
If one has been evaluated by a urologist and undergone a variety of tests for problems and finasteride has been single out as the cause. Can one still undergo restoration work? Or should one simply forget it?
You are asking for a medical opinion without my ability to find out details about you, something that I do when I perform a consultation. Things like family history, age, miniaturization (where it is and how advanced it is) will tell me much. One can have a hair transplant without taking Propecia. I do this in older men and in men who I can predict what will happen to them over time. Everyone is different. My job is to protect you from over-enthusiasm, bring you down to reality, and then try to accomplish your goals (which may or may not be a hair transplant).