Category: Uncategorized

Can you see the surgery?

Children mistakenly given oral minoxidil in place of stomach ailment drug

https://www.yahoo.com/news/spanish-parents-demand-compensation-children-153113188.html

Male pattern balding with recession is often asymmetrical. The side that is behind will often catch up with the more receded side.

This is my math: 6000 donor follicles available. Average head has 100000 hairs. Can lose 50% of hair density before it’s visible. Say a norwood 6 loses 60% of their hair (40% left on sides) that’s 60000 hairs. Need 30000 hairs replaced to reach 50% density and look like a full head. Average graft 2 hairs. 15000 grafts = 30000 hairs would look like a full head. Could sides be over harvested from 6000 to 10000 to replace 20000 hairs? 2/3 of full apperance. Sides clipped to no1 with SMP to cover overharvest?

Answer: ?Your math is partly right. The donor area is always determined on the Class 7 scale not the Class 6 scale, which essentially reduces the donor area to about 20,000 hairs or 10,000 grafts, which can be harvested at say 60% assuming that you have an average donor density. Graft numbers are adjusted according to hair weight (coarse vs fine), color and contract between hair and scalp and hair character. The artistic judgment of the surgeon manages the multi-variant analysis as everything is not by the numbers alone.

Torey Lanez hair transplant is looking great… I’m so happy for him. from tressless

https://www.sandiegouniontribune.com/business/biotech/sdut-hair-stem-cells-papillae-gnedeva-terskikh-burnham-2015jan26-story.html

This has been done before. I remember attending a lecture which described these cells put into mice and since the direction couldn’t be controlled, the mice all died from ingrown hair infections

Combining finasteride and minoxidil is a good idea. You should get a HAIRCHECK instrument test to find out exactly what hair you are losing and how these drugs reverse the process. IF you are in Southern California, my first visit for this test is free

Another photo of a man who had FUE and as a result had an over-harvested donor area. The donor area that was harvested was larger than the permanent zone so some of the transplanted hairs will not be permanent and may fall out in time. This depleted donor area could be treated with scalp micropigmentation

Human steroid 5 alpha-reductase type II is a prostate-specific, membrane-associated enzyme that catalyzes the conversion of testosterone to dihydrotestosterone, the most potent androgen in the prostate gland. Genetic variants of this enzyme have been associated with both the development and the progression of prostate cancer. Both finasteride and dutasteride are competitive inhibitors of the type II steroid 5 alpha-reductase that have been effectively used for the treatment of benign prostatic hyperplasia. Finasteride has also been successfully utilized for prostate cancer chemoprevention. We here investigate 5 alpha-reductase inhibition assays in vitro to measure the effect of incubation time on the apparent inhibition constant (K_i) for both constitutional and somatic (prostate cancer) enzyme variants. Our systematic pharmacogenetic analysis shows that both finasteride and dutasteride are slow, time-dependent inhibitors of steroid 5 alpha-reductase type II, and that the inhibition kinetics depend on the 5 alpha-reductase genotype. We also show that, overall, dutasteride is a more efficient steroid 5 alpha-reductase inhibitor than finasteride. Based on our data, we are able to map areas of the enzyme that are responsible for this time-dependent inhibition for either (or both) enzyme inhibitor(s). This comprehensive pharmacogenetic analysis of steroid 5 alpha-reductase variants unveiled significant pharmacogenetic variation for both finasteride and dutasteride and thus should be taken into account when designing protocols for treatment and/or chemoprevention of prostatic diseases with either one of these 5 alpha-reductase inhibitors since there is considerable pharmacogenetic variation for both drugs.