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New 10 year Finasteride Study from Japan

https://www.oatext.com/Long-term-(10-year)-efficacy-of-finasteride-in-523-Japanese-men-with-androgenetic-alopecia.php

RESULTS: We evaluated the long-term (10-year) efficacy and safety of AGA treatment with 1 mg/day finasteride in a large study population (532 patients), as the first study of this kind in Japan, to our knowledge. A high objective efficacy was demonstrated by the MGPA, which revealed improvement and prevention of disease progression in 99.1% of the 532 Japanese men with AGA treated with 1 mg/day finasteride for 10 years.

SEXUAL FUNCTION: In the investigation in 40 years or older of Asians, the incidences of decreased libido and erectile dysfunction were 6.0–38.7% and 40.6–70.0%, respectively [29,23]. Overall, the adverse reactions were all mild, and the incidence was lower than the generic incidence of decreased libido and erectile dysfunction in Asians. As adverse reactions were recorded by patients in a subjective questionnaire, the result was thought to be slightly different from the correct number of adverse reactions in this study

Dr. Rassman’s Comment: The efficacy of long term finasteride treatment has been published many times. When compared side-by-side with men who did not take finasteride, the results show that men with genetic balding hold on to more hair over time than the non-finasteride counterparts. The issue of sexual dysfunction is briefly discussed and the comment that the sexual side effects of age parallel the sexual side effects while on the drug (just slightly less according to this study). There were no cases of Past-finasteride syndrome reported in this study, a significant point.

 

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2021-03-08 19:55:47New 10 year Finasteride Study from Japan

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Can Propecia Counter the Side Effect Risk from My Antidepressant?

I am starting to take an anti-depressant that is potentially linked to hair loss as a side effect. I am on propecia and minox. I was interested in knowing if these drugs will most likely counter the effects of hairloss related to anti depressants. I know that propecia can combat shock loss after a transplant, so I am just using some logic that this may alleviate this concern of mine?

It’s not likely. The hair loss that comes as a side effect of various medications is different than hair loss that’s a direct result of genetic balding. That being said, I wouldn’t expect Propecia (finasteride) would really help any hair loss related to antidepressants.

But since you’ve already been taking Propecia, talk to your prescribing doctor about staying on it to continue the battle against the genetic loss.

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New Propecia Persistent Sexual Side Effects Study Published

Snippet from the study abstract:

Methods. We conducted standardized interviews with 71 otherwise healthy men aged 21–46 years who reported the new onset of sexual side effects associated with the temporal use of finasteride, in which the symptoms persisted for at least 3 months despite the discontinuation of finasteride.

Results.  Subjects reported new-onset persistent sexual dysfunction associated with the use of finasteride: 94% developed low libido, 92% developed erectile dysfunction, 92% developed decreased arousal, and 69% developed problems with orgasm. The mean number of sexual episodes per month dropped and the total sexual dysfunction score increased for before and after finasteride use according to the Arizona Sexual Experience Scale (P < 0.0001 for both). The mean duration of finasteride use was 28 months and the mean duration of persistent sexual side effects was 40 months from the time of finasteride cessation to the interview date. Study limitations include a post hoc approach, selection bias, recall bias for before finasteride data, and no serum hormone levels.[/bq]
Read the full abstract — Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss

This is new to me. We always try to follow publications, but remember that just because an article is published does not mean it is FACT and everyone needs to understand how the results were compiled. This was a paper based only on interviews of 71 men with sexual side effects only. I’m unsure about what lengths they went to find any underlying health issues or even conducting physical exams.

If this is true, then those men who develop sexual side effects will have a difficult decision. This has not been my experience in using and prescribing this drug for over 14 years. We have to make our decisions not just based on what we read, but also the methods of how the conclusions were based.

More info can be found at Time.com.

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Can rice water grow hair?

According to Google Search: “The amino acids present in rice water, in particular, help in the regeneration of hair and aid faster growth of your hair. Also, rice water contains vitamins B, C, and E, which further help in hair growth (7). The best way to use rice water to grow hair is to rinse your hair with it after a wash.Oct 25, 2017″. Instructions follow in this link on how to use Rice Water: https://www.google.com/search?q=rice+water+and+hair+growth&oq=rice+water+and+hair+growth&aqs=chrome.0.69i59j0l5.5077j0j7&sourceid=chrome&ie=UTF-8


2019-02-01 15:22:05Can rice water grow hair?

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Can Someone Control DHT?

HI DR. RASSMAN, I have a question for you…. you say propecia slows the hairloss, but mphl still progresses. I would like to know why the radio show host Spencer Kobren (The Bald Truth) has been able to stop his hair loss for 11 yrs now. Is he from another planet, or someone very special because he say that DHT is scared of him???? I mean you say the studies on merck site show hairloss continues even on the drug but yet I know Spencer has stop his hairloss. I think you might be reading that propecia curve wrong. I believe that when you start taking propecia you ” SHOCK THE SYSTEM” and you hairs go into a angen phase so appears like more hair is growing in the first 2 yrs but are hair does not stay in that phase forever . The hair on our head is not all in sync at the same time. I would also like to point out that the graph shows hair that was grow from vellus hair and does not count the hair that was maintain.. like the the terminal hair. That means at 5 yrs you will have 277 more hairs then when you started but what about all the hair you maintained. There is a difference between maintenance and the growing of lost hair. He has kept his so I think that proves his point, don’t you? DO I make sense..

What you’re saying is speculation based upon little fact. You are confusing things like vellus hair and miniaturized hair. The vellus hair is in each follicular unit (with or without balding present) and miniaturized hair is hair that is impacted by the genetic balding process. All hair goes into anogen, the longest part of its growing cycle and it may last years. You are implying that vellus hairs grow into normal hair on Propcia, but that is not a fact that I am aware of. One can not put all of the pieces together the way you did. The fact that Spencer did not lose his hair may have been in his genetic cards, and certainly not because he “scared” his DHT away. I would not say that former President Bill Clinton “mastered” keeping his hair or that he “frightened” his DHT, even with the Pentagon behind him. Sorry, but I have little to add.


2005-10-05 15:30:12Can Someone Control DHT?

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No More Morning Erections After Taking Propecia for a Month

I’ve been on Propecia for just over a month, and I realized I don’t get morning erections anymore. (I know for a fact I got them before) Is this something to worry about?

I’m only 21 and any change in sexual function for me is something I want to pay close attention to. Do you think this is just my body trying to adjust to the drug?

Sexual function has a very complicated mechanism and several factors are involved. The most important factor is usually stress that often could be seen with acceleration of hair loss. One way that you can see if your sexual function changes are due to the new medication is to stop it and monitor the changes. Are you having difficulty maintaining and getting an erection?


2007-03-27 10:36:07No More Morning Erections After Taking Propecia for a Month

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Can Topical Acne Cream Cause Hair Loss?

Can Tetracycline and or Tazoric/Differin facial cream (for acne) cause hair loss? I am a 21 year old male and I have been losing hair quite rapidly, got tested for thyroid disease and low iron and my tests came out fine. I was wondering if these medications are used long term (2-3 years or longer) can they cause hair loss? There are people in my family with MPB but they all started baldling later in life (40s or later). Thank you so much for your time doctor! Hope to hear from you soon.

While hair loss is not listed as a side effect on the documentation for tetracycline, Tazorac (tazarotene), or Differin (adapalene), there are some unconfirmed reports about hair loss and Differin that I found on a message board. Take this for what you will. Once again, these are unconfirmed reports.

The most common cause of hair loss in males is genetic hair loss. If you are concerned about genetic hair loss, you need to see a doctor who can examine your hair under a microscope (miniaturization study) and assess the pattern at which you are losing your hair. There are medical and/or surgical options.

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Normal shed

How many amounts of hair is considered a shed? I have been on finasteride for 2 years, I had some shed in the couple of first months but not ever since. I had 0 hairs, when I brushed my hands through my hair after shower. I noticed in the couple last weeks, that I am getting around 10-30 hairs when running my hands through my hair

Normal shedding is about 100 hairs per day. Multiply that out for 3 years and you will understand the turnover of the average persons hair as the typical anagen cycle would be 3 years. For shorter anagen cycles, the shed will be greater. Some younger women will have significantly less shed if their anagen cycle is longer like 4-5 years.